1-[(9Z,12Z)-heptadeca-9,12-dienyl]-4-[2-[[(9Z,12Z)-heptadeca-9,12-dienyl]-[(9Z,12Z)-octadeca-9,12-dienyl]amino]ethyl]-N,N-bis[(9Z,12Z)-octadeca-9,12-dienyl]piperazin-2-amine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 英文名称: 1-[(9Z,12Z)-heptadeca-9,12-dienyl]-4-[2-[[(9Z,12Z)-heptadeca-9,12-dienyl]-[(9Z,12Z)-octadeca-9,12-dienyl]amino]ethyl]-N,N-bis[(9Z,12Z)-octadeca-9,12-dienyl]piperazin-2-amine
• 化学式: C₉₄H₁₇₂N₄
• 分子量: 1358.4
• InChiKey: INWRMBXASMMIBX-RTUWZEOASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  35.3
• 重原子数：
  98
• 可旋转键数：
  77
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.79
• 拓扑面积：
  13
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• NOVEL LIPIDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF BIOLOGICALLY ACTIVE COMPOUNDS
  申请人：AXOLABS GMBH

  公开号：US20140170175A1

  公开（公告）日：2014-06-19

  The present invention provides novel amino-lipids, compositions comprising such amino-lipids and methods of producing them. In addition, lipid nanoparticles comprising the novel amino-lipids and a biologically active compound are provided, as well as methods of production and their use for intracellular drug delivery.
• US9149531B2
  申请人：——

  公开号：US9149531B2

  公开（公告）日：2015-10-06