1,4-Dimethyl-2-(2-methylpropoxymethyl)piperazine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 英文名称: 1,4-Dimethyl-2-(2-methylpropoxymethyl)piperazine
• 英文别名: 1,4-dimethyl-2-(2-methylpropoxymethyl)piperazine
• 化学式: C₁₁H₂₄N₂O
• 分子量: 200.32
• InChiKey: FIDNKORESXYXKM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  15.7
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• METHODS OF TARGETED TREATMENT OF FRONTOTEMPORAL LOBAR DEGENERATION
  申请人：Patzke Holger

  公开号：US20140179678A1

  公开（公告）日：2014-06-26

  The present invention provides targeted treatment to subjects suffering from Frontotemporal lobar degeneration through use of FTLD targeted agents, as described in the present invention. In particular, the FTLD targeted agents provided herein demonstrate high brain penetration, which decreases risk issues associated with peripheral administration. Furthermore, the FTLD targeted agents of the present invention, when administered to a subject selected for treatment based on the results of a FTLD diagnostic assay, offer targeted treatment of FTLD.