N-(3,4-dichlorophenyl)-4-phenylpiperazine-1-carbothioamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 英文名称: N-(3,4-dichlorophenyl)-4-phenylpiperazine-1-carbothioamide
• 化学式: C₁₇H₁₇Cl₂N₃S
• 分子量: 366.3
• InChiKey: QLVRCPDRCDCLNO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  23
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  50.6
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Anti-Arenaviral Compounds
  申请人：Amberg Sean M.

  公开号：US20120308519A1

  公开（公告）日：2012-12-06

  Described herein are 4-methyl-piperazine-1-carbothioic acid amide derivatives and analogs, as well as compositions containing the same, for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases caused by hemorrhagic fever viruses, such as Arenaviruses.
• ANTI-ARENAVIRAL COMPOUNDS
  申请人：SIGA TECHNOLOGIES, INC.,

  公开号：US20140301979A1

  公开（公告）日：2014-10-09

  Described herein are 4-methyl-piperazine-1-carbothioic acid amide derivatives and analogs, as well as compositions containing the same, for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases caused by hemorrhagic fever viruses, such as Arenaviruses.
• US8791110B2
  申请人：——

  公开号：US8791110B2

  公开（公告）日：2014-07-29