Ethyl 2-(cyclohexen-1-yl)-3-[3,5-dimethylhexan-3-ylcarbamoyl(methyl)amino]-2-methylpropanoate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机碳酸及其衍生物
• 英文名称: Ethyl 2-(cyclohexen-1-yl)-3-[3,5-dimethylhexan-3-ylcarbamoyl(methyl)amino]-2-methylpropanoate
• 英文别名: ethyl 2-(cyclohexen-1-yl)-3-[3,5-dimethylhexan-3-ylcarbamoyl(methyl)amino]-2-methylpropanoate
• 化学式: C₂₂H₄₀N₂O₃
• 分子量: 380.6
• InChiKey: XTSNLFQWTORTGP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  27
• 可旋转键数：
  10
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  58.6
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• COMPOUNDS USEFUL AS MODULATORS OF TRPM8
  申请人：Senomyx, Inc.

  公开号：EP2958897A2

  公开（公告）日：2015-12-30
• [EN] COMPOUNDS USEFUL AS MODULATORS OF TRPM8<br/>[FR] COMPOSÉS UTILES COMME MODULATEURS DE TRPM8
  申请人：SENOMYX INC

  公开号：WO2014130582A2

  公开（公告）日：2014-08-28

  The present invention includes compounds useful as modulators of TRPM8, such as compounds of Formulae (Ia), (Ib) and (Ic), and the subgenus and species thereof; personal products containing those compounds; and the use of those compounds and the personal products, particularly the use of increasing or inducing chemesthetic sensations, such as cooling or cold sensations.