1-Formyl-piperidine-3-carboxylic acid ethyl ester

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: 1-Formyl-piperidine-3-carboxylic acid ethyl ester
• 英文别名: ethyl 1-formylpiperidine-3-carboxylate
• 化学式: C₉H₁₅NO₃
• 分子量: 185.22
• InChiKey: QEXNJNFVDLMARJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  46.6
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• Carbazole derivatives and their use as neuropeptide y5 receptor ligands
  申请人：——

  公开号：US20040067999A1

  公开（公告）日：2004-04-08

  Compounds of formula (I): are described wherein R 1 -R 6 and m are as defined within. Processes for their preparation and their use as NPY 5 inhibitors is described.

  描述了化学式（I）的化合物，其中R1-R6和m的定义如所述。描述了它们的制备过程以及它们作为NPY 5抑制剂的用途。
• Novel bicyclic hydroxamates as inhibitors of histone deacetylase
  申请人：Leahy M Ellen

  公开号：US20060058553A1

  公开（公告）日：2006-03-16

  The present invention is directed to certain bicyclic hydroxamate derivatives that are inhibitors of histone deacetylase and are therefore useful in the treatment of diseases associated with histone deacetylase activity. Pharmaceutical compositions and processes for preparing these compounds are also disclosed

  本发明涉及某些双环羟肟衍生物，它们是组蛋白去乙酰化酶的抑制剂，因此可以用于治疗与组蛋白去乙酰化酶活性相关的疾病。本发明还公开了制备这些化合物的制药组合物和过程。
• CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS
  申请人：AstraZeneca AB

  公开号：EP1358157A1

  公开（公告）日：2003-11-05
• NOVEL BICYCLIC HYDROXAMATES AS INHIBITORS OF HISTONE DEACETYLASE
  申请人：Axys Pharmaceuticals

  公开号：EP1472216A2

  公开（公告）日：2004-11-03
• THERAPEUTIC ISOXAZOLE COMPOUNDS
  申请人：Dart Neuroscience (Cayman) Ltd

  公开号：EP2182809B1

  公开（公告）日：2018-01-17