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    首页 分子通 4-(2,3-dihydro-1H-indol-1-ylsulfonyl)-2,1,3-benzothiadiazole

    4-(2,3-dihydro-1H-indol-1-ylsulfonyl)-2,1,3-benzothiadiazole

    分子结构分类

    有机化合物 - 有机杂环化合物 - 苯并噻二唑类
    中文名称
    ——
    中文别名
    ——
    英文名称
    4-(2,3-dihydro-1H-indol-1-ylsulfonyl)-2,1,3-benzothiadiazole
    英文别名
    4-(2,3-dihydroindol-1-ylsulfonyl)-2,1,3-benzothiadiazole
    4-(2,3-dihydro-1H-indol-1-ylsulfonyl)-2,1,3-benzothiadiazole化学式
    CAS
    ——
    化学式
    C14H11N3O2S2
    mdl
    ——
    分子量
    317.4
    InChiKey
    JAVLOGBQHADBOA-UHFFFAOYSA-N
    BEILSTEIN
    ——
    EINECS
    ——
    • 物化性质
    • 计算性质
    • ADMET
    • 安全信息
    • SDS
    • 制备方法与用途
    • 上下游信息
    • 反应信息
    • 文献信息
    • 表征谱图
    • 同类化合物
    • 相关功能分类
    • 相关结构分类

    计算性质

    • 辛醇/水分配系数(LogP)：
      2.5
    • 重原子数：
      21
    • 可旋转键数：
      2
    • 环数：
      4.0
    • sp3杂化的碳原子比例：
      0.14
    • 拓扑面积：
      99.8
    • 氢给体数：
      0
    • 氢受体数：
      6

    文献信息

    • Microrna modulators and method for identifying and using the same
      申请人：Huang Qihong
      公开号：US20100196357A1
      公开（公告）日：2010-08-05
      The present invention is a method for identifying agents which modulate microRNA activity. The invention involves contacting a cell harboring a microRNA and a microRNA binding sequence, which is operably linked to a nucleic acid molecule encoding a reporter protein, with a test agent and determining whether the test agent increases or decreases the expression of the reporter protein thereby identifying a microRNA modulator. Antagonists identified by this screening assay are provided, as are methods for using the same to inhibit microRNA activity and prevent or treat disease.
    • MicroRNA Modulators and Method for Identifying And Using The Same
      申请人：Huang Qihong
      公开号：US20120010177A1
      公开（公告）日：2012-01-12
      The present invention is a method for identifying agents which modulate microRNA activity. The invention involves contacting a cell harboring a microRNA and a microRNA binding sequence, which is operably linked to a nucleic acid molecule encoding a reporter protein, with a test agent and determining whether the test agent increases or decreases the expression of the reporter protein thereby identifying a microRNA modulator. Antagonists identified by this screening assay are provided, as are methods for using the same to inhibit microRNA activity and prevent or treat disease.
    • MicroRNA Modulators and Method for Identifying and Using the Same
      申请人：Huang Qihong
      公开号：US20130023498A1
      公开（公告）日：2013-01-24
      The present invention is a method for identifying agents which modulate microRNA activity. The invention involves contacting a cell harboring a microRNA and a microRNA binding sequence, which is operably linked to a nucleic acid molecule encoding a reporter protein, with a test agent and determining whether the test agent increases or decreases the expression of the reporter protein thereby identifying a microRNA modulator. Antagonists identified by this screening assay are provided, as are methods for using the same to inhibit microRNA activity and prevent or treat disease.
    • US20140255386A1
      申请人：——
      公开号：US20140255386A1
      公开（公告）日：2014-09-11
    • [EN] MICRORNA MODULATORS AND METHOD FOR IDENTIFYING AND USING THE SAME<br/>[FR] MODULATEURS DE MICROARN ET MÉTHODE D'IDENTIFICATION ET D'UTILISATION ASSOCIÉE
      申请人：WISTAR INST
      公开号：WO2013019469A1
      公开（公告）日：2013-02-07
      The present invention is a method for identifying agents which modulate microRNA activity. The invention involves contacting a cell harboring a microRNA and a microRNA binding sequence, which is operably linked to a nucleic acid molecule encoding a reporter protein, with a test agent and determining whether the test agent increases or decreases the expression of the reporter protein thereby identifying a microRNA modulator. Antagonists identified by this screening assay are provided, as are methods for using the same to inhibit microRNA activity and prevent or treat disease.
    查看更多

    同类化合物

    （5-氯-2,1,3-苯并噻二唑-4-基）-氨基甲氨基硫代甲酸甲酯一氢碘 阿拉酸式苯-S-甲基 阿拉酸式苯 试剂4,7-Bis(5-bromo-2-thienyl)-5,6-bis(dodecyloxy)-2,1,3-benzothiadiazole 苯并恶唑-6-胺 苯并[d][1,2,3]噻二唑-6-羧酸 苯并[C][1,2,5]噻二唑-5-硼酸频那醇酯 苯并[C][1,2,5]噻二唑-4-磺酸钠 苯并[C][1,2,5]噻二唑-4-基甲醇 苯并[C][1,2,5]噻二唑-4,7-二基二硼酸 苯并[1,2,5]噻二唑-4-羧酸 苯并[1,2,5]噻二唑-4-磺酰氯 苯并[1,2,3]噻二唑-7-基胺 苯并[1,2,3]噻二唑-6-羧酸甲酯 苯并[1,2,3]噻二唑-5-基胺 苯并[1,2,3]噻二唑-4-基胺 苯2,1,3-噻重氮-5-羧酸酯 碘化(2,1,3-苯并硫杂(SIV)二唑-5-基)二甲基八氧代甲基铵 硫代磷酸S-[(2,1,3-苯并噻二唑-5-基)甲基]酯O,O-二钠盐 盐酸替扎尼定-d4 盐酸替扎尼定 灭草荒 替托尼定D4 替扎尼定杂质1 替扎尼定 噻唑并[4,5-f]-2,1,3-苯并噻二唑,6-甲基-(6CI,8CI) 去氢替扎尼定 全氟苯并[c][1,2,5]噻二唑 [7-[2-[2-(8-硫杂-7,9-二氮杂双环[4.3.0]壬-3,5,9-三烯-7-基)乙基二巯基]乙基]-8-硫杂-7,9-二氮杂双环[4.3.0]壬-3,5,9-三烯-2-基]甲胺 N-甲氧基-N-甲基-2,1,3-苯并噻二唑-5-酰胺 N-(5-氯-2,1,3-苯并噻二唑-4-基)硫脲 N,N'-二硫代二(亚乙基)二(2,1,3-苯并噻二唑-5-甲胺) N'-2,1,3-苯并噻二唑-4-基-N,N-二甲基酰亚胺基甲酰胺 BTQBT(升华提纯) 7H-咪唑并[4,5-g][1,2,3]苯并噻二唑 7H-咪唑并[4,5-e][1,2,3]苯并噻二唑 7-肼基[1,3]噻唑并[4,5-e][2,1,3]苯并噻二唑 7-硝基-苯并[1,2,5]噻二唑-4-基胺 7-硝基-1,2,3-苯并噻二唑 7-甲基[1,3]噻唑并[5,4-e][2,1,3]苯并噻二唑 7-甲基[1,3]噻唑并[4,5-e][2,1,3]苯并噻二唑 7-甲基[1,3]噻唑并[4,5-e][1,2,3]苯并噻二唑 7-溴苯并[c][1,2,5]噻二唑-4-磺酸 7-溴-苯并[D][1,2,3]噻二唑 7-溴-5-甲基-4-硝基-2,1,3-苯并噻二唑 7-溴-4-醛基苯并[C][1,2,5]噻二唑 7-溴-2,1,3-苯并噻二唑-4-磺酰氯 7-溴-2,1,3-苯并噻二唑-4-甲腈 7-溴-2,1,3-苯并噻二唑-4-亚磺酸 7-氯-苯并[1,2,5]噻二唑-4-基胺

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