N-(3-chlorophenyl)-4-(4-nitrophenyl)piperazine-1-carboxamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 英文名称: N-(3-chlorophenyl)-4-(4-nitrophenyl)piperazine-1-carboxamide
• 化学式: C17H17ClN4O3
• mdl: MFCD00248280
• 分子量: 360.8
• InChiKey: VUHDRDOYRQRLIG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  25
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  81.4
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• Use of Inhibitors of Scavenger Receptor Class Proteins for the Treatment of Infectious Diseases
  申请人：Hannus Michael

  公开号：US20090324580A1

  公开（公告）日：2009-12-31

  The present invention relates to the use of inhibitors of scavenger receptor class proteins, in particular ScarB1 for the production of a medicament for treatment of and/or prophylaxis against infections, involving liver cells and/or hematopoietic cells, in particular malaria.
• USE OF INHIBITORS OF SCAVENGER RECEPTOR CLASS PROTEINS FOR THE TREATMENT OF INFECTIOUS DISEASES
  申请人：HANNUS MICHAEL

  公开号：US20120276121A1

  公开（公告）日：2012-11-01

  The present invention relates to the use of inhibitors of scavenger receptor class proteins, in particular ScarB1 for the production of a medicament for treatment of and/or prophylaxis against infections, involving liver cells and/or hematopoietic cells, in particular malaria.
• US8507546B2
  申请人：——

  公开号：US8507546B2

  公开（公告）日：2013-08-13
• [EN] CYCLIC UREA COMPOUNDS AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS EFFECTIVE FOR THE TREATMENT OF CARDIOVASCULAR DISORDERS<br/>[FR] COMPOSES D'UREE CYCLIQUES COMME INHIBITEURS D'EPOXYDE HYDROLASE SOLUBLES EFFECTIFS DANS LE TRAITEMENT DE MALADIES CARDIOVASCULAIRES
  申请人：BOEHRINGER INGELHEIM INT

  公开号：WO2007106706A1

  公开（公告）日：2007-09-20

  [EN] Disclosed are methods of using soluble epoxide hydrolase (sEH) inhibitors for treating diseases related to cardiovascular disease.
  [FR] La présente invention concerne des procédés d'utilisation d'inhibiteurs d'époxyde hydrolase soluble (sEH) pour traiter des maladies liées à une maladie cardiovasculaire.