5-[4-(2-Fluorobenzoyl)-1-piperazinyl]-8-nitroquinoline

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 英文名称: 5-[4-(2-Fluorobenzoyl)-1-piperazinyl]-8-nitroquinoline
• 英文别名: (2-fluorophenyl)-[4-(8-nitroquinolin-5-yl)piperazin-1-yl]methanone
• 化学式: C20H17FN4O3
• mdl: MFCD02070660
• 分子量: 380.4
• InChiKey: SWGLCSKVQGGDNQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  28
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  82.3
• 氢给体数：
  0
• 氢受体数：
  6

文献信息

• Compositions and methods for modulating interaction between polypeptides
  申请人：Kazantsev G. Aleksey

  公开号：US20050239833A1

  公开（公告）日：2005-10-27

  The present invention is based, in part, on assays we conducted that revealed compounds that may be used to treat or prevent diseases characterized by an abnormal or undesirable association of one protein with another.

  本发明部分基于我们所进行的检测，这些检测揭示了可用于治疗或预防以一种蛋白质与另一种蛋白质的异常或不良结合为特征的疾病的化合物。
• COMPOSITIONS AND METHODS FOR MODULATING INTERACTION BETWEEN POLYPEPTIDES
  申请人：The General Hospital Corporation

  公开号：US20130203733A1

  公开（公告）日：2013-08-08

  The present invention is based, in part, on assays we conducted that revealed compounds that may be used to treat or prevent diseases characterized by an abnormal or undesirable association of one protein with another.
• Sirtuin Modulators as Inhibitors of Cytomegalovirus
  申请人：The Trustees of Princeton University

  公开号：US20160296523A1

  公开（公告）日：2016-10-13

  Agents and methods of inhibiting or improving the growth of viruses are provided.
• US8404747B2
  申请人：——

  公开号：US8404747B2

  公开（公告）日：2013-03-26
• [EN] COMPOSITIONS AND METHODS FOR MODULATING INTERACTION BETWEEN POLYPEPTIDES<br/>[FR] COMPOSITIONS ET PROCEDES POUR MODULER L'INTERACTION ENTRE DES POLYPEPTIDES
  申请人：GEN HOSPITAL CORP

  公开号：WO2005087217A1

  公开（公告）日：2005-09-22

  The present invention is based, in part, on assays we conducted that revealed compounds that may be used to treat or prevent diseases characterized by an abnormal or undesirable association of one protein with another.