1-(4-Methylpiperazin-1-yl)-3-propan-2-yloxypropan-2-ol

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 英文名称: 1-(4-Methylpiperazin-1-yl)-3-propan-2-yloxypropan-2-ol
• 化学式: C₁₁H₂₄N₂O₂
• 分子量: 216.32
• InChiKey: HZMRZZYDBJSKSR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  15
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  35.9
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• Thiazolyl-Benzimidazoles
  申请人：Cai Jianping

  公开号：US20100160308A1

  公开（公告）日：2010-06-24

  The invention is directed to compounds of formula (1) and pharmaceutically acceptable salts thereof, methods for the preparation thereof, and methods of use thereof.

  这项发明涉及到式（1）的化合物及其药用可接受盐，其制备方法和使用方法。
• N-substituted tricyclic 1-aminopyrazoles as inhibitors for the treatment of cell proliferative disorders
  申请人：Ho Yung Chih

  公开号：US20070142305A1

  公开（公告）日：2007-06-21

  The invention is directed to N-substituted tricyclic 3-AMINOPYRAZOLE derivatives, which are useful as inhibitors of platelet-derived growth factor receptor (PDGF-R) kinase, and methods for the preparation of said derivatives. The present invention is further directed to pharmaceutical compositions comprising the compounds of the present invention and to methods for treating conditions such as tumors and other cell. proliferative disorders.

  本发明涉及N-取代的三环3-氨基吡唑衍生物，其可用作血小板源性生长因子受体（PDGF-R）激酶的抑制剂，以及制备该衍生物的方法。本发明进一步涉及包含本发明化合物的制药组合物，并用于治疗肿瘤和其他细胞增殖性疾病的方法。
• QUATERNARY AMMONIUM HYDROXIDES
  申请人：Little Charles B.

  公开号：US20130261039A1

  公开（公告）日：2013-10-03

  A method of removing a residue from a surface, including applying to the surface a composition including (a) a quaternary ammonium hydroxide having a general formula (I): as defined herein, and (b) a dipolar aprotic solvent substantially free of water; and removing at least a substantial portion of the residue from the surface.
• US7196110B2
  申请人：——

  公开号：US7196110B2

  公开（公告）日：2007-03-27
• US7795440B2
  申请人：——

  公开号：US7795440B2

  公开（公告）日：2010-09-14