1-methyl-4-[(3-phenyladamantan-1-yI)carbonyl]piperazine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 英文名称: 1-methyl-4-[(3-phenyladamantan-1-yI)carbonyl]piperazine
• 英文别名: 1-methyl-4-[{(3-phenyladamantan-1-yl)carbonyl}]piperazine；(4-Methylpiperazin-1-yl)-(3-phenyl-1-adamantyl)methanone
• 化学式: C₂₂H₃₀N₂O
• 分子量: 338.493
• InChiKey: HEXBCLIICFLVHG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  25
• 可旋转键数：
  2
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.68
• 拓扑面积：
  23.6
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• [EN] ADAMATANE DERIVATIVES FOR THE TREATMENT OF FILOVIRUS INFECTION<br/>[FR] DÉRIVÉS D'ADAMATANE POUR LE TRAITEMENT D'UNE INFECTION À FILOVIRUS
  申请人：ARISAN THERAPEUTICS

  公开号：WO2017127306A1

  公开（公告）日：2017-07-27

  Compounds of structural Formula (I) were developed for the treatment of infections by filoviruses including Ebolavirus and Marburgvirus.
• [EN] ADAMANTANE AMIDES AND THIOAMIDES FOR THE TREATMENT OF EBOLAVIRUS INFECTION<br/>[FR] AMIDES ET THIOAMIDES D'ADAMANTANE POUR LE TRAITEMENT D'UNE INFECTION PAR LE VIRUS EBOLA
  申请人：[en]ARISAN THERAPEUTICS INC.

  公开号：WO2021262426A2

  公开（公告）日：2021-12-30

  Compounds of Structural Formulae I, II, III, IV, V, VI, VIa, VIb, VII, and VIII were developed for the treatment of Ebolavirus infection, wherein, R1, R2, R8, X, Y, Q, W, and NR3aR3bare defined in the specification.