2,6-Bis-<5-methyl-thenyliden-(2)>-cyclohexanon | 101789-34-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 噻吩类
• 英文名称: 2,6-Bis-<5-methyl-thenyliden-(2)>-cyclohexanon
• 英文别名: 2,6-Bis[(5-methylthiophen-2-yl)methylidene]cyclohexan-1-one
• CAS: 101789-34-8
• 化学式: C₁₈H₁₈OS₂
• 分子量: 314.472
• InChiKey: CBTLOJPWSRXZDD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  21
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.28
• 拓扑面积：
  73.6
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  5-甲基-2-噻吩甲醛 、 环己醇 在 Wilkinson's catalyst 、 三氟化硼乙醚 作用下， 以 甲苯 为溶剂， 以91%的产率得到2,6-Bis-<5-methyl-thenyliden-(2)>-cyclohexanon
  参考文献：
  名称：

  A RhCl(PPh3)3/BF3·OEt2 co-promoted direct C–C cross-coupling of alcohols at β-position with aldehydes

  摘要：

  A novel RhCl(PPh3)(3)/BF3 center dot OEt2 co-promoted direct C-C cross-coupling of primary and secondary alcohols at beta-position with aldehyde was developed. This reaction could provide an efficient synthesis of a series of alpha, beta-unsaturated aldehydes and diarylidene ketones, just from simple and easily available alcohols and aldehydes. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.05.006

文献信息

• A RhCl(PPh3)3/BF3·OEt2 co-promoted direct C–C cross-coupling of alcohols at β-position with aldehydes
  作者：Shu-Yu Zhang、Yong-Qiang Tu、Chun-An Fan、Ming Yang、Fu-Min Zhang

  DOI：10.1016/j.tetlet.2009.05.006

  日期：2009.7

  A novel RhCl(PPh3)(3)/BF3 center dot OEt2 co-promoted direct C-C cross-coupling of primary and secondary alcohols at beta-position with aldehyde was developed. This reaction could provide an efficient synthesis of a series of alpha, beta-unsaturated aldehydes and diarylidene ketones, just from simple and easily available alcohols and aldehydes. (C) 2009 Elsevier Ltd. All rights reserved.