tert-Butyl-[1-(3-chloro-prop-1-ynyl)-tetradecyloxy]-dimethyl-silane | 220344-53-6

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 英文名称: tert-Butyl-[1-(3-chloro-prop-1-ynyl)-tetradecyloxy]-dimethyl-silane
• 英文别名: Tert-butyl-(1-chloroheptadec-2-yn-4-yloxy)-dimethylsilane
• CAS: 220344-53-6
• 化学式: C₂₃H₄₅ClOSi
• 分子量: 401.148
• InChiKey: FYXYODOSLAPSMH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.32
• 重原子数：
  26
• 可旋转键数：
  15
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.91
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  tert-Butyl-[1-(3-chloro-prop-1-ynyl)-tetradecyloxy]-dimethyl-silane 在 四丁基氟化铵 作用下， 生成 (4S,5S)-4-((S)-1,2-Dihydroxy-ethyl)-3-methylene-5-tridecyl-dihydro-furan-2-one
  参考文献：
  名称：

  Efficient total syntheses of (±)protolichesterinic acid and (±)rocellaric acid via tungsten-π-allyl complexes

  摘要：

  Total syntheses of racemic protolichesterinic acid (1) and rocellaric add (2) were achieved with the use of tungsten-pi-allyl complex in the key step. In this synthetic route, compounds 1 and 2 were prepared in four and six steps respectively starting from readily available chloropropargyl derivatives. (C) 1998 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(98)02146-7
• 作为产物：
  描述：

  肉豆蔻醛 在 咪唑 、 正丁基锂 作用下， 生成 tert-Butyl-[1-(3-chloro-prop-1-ynyl)-tetradecyloxy]-dimethyl-silane
  参考文献：
  名称：

  Efficient total syntheses of (±)protolichesterinic acid and (±)rocellaric acid via tungsten-π-allyl complexes

  摘要：

  Total syntheses of racemic protolichesterinic acid (1) and rocellaric add (2) were achieved with the use of tungsten-pi-allyl complex in the key step. In this synthetic route, compounds 1 and 2 were prepared in four and six steps respectively starting from readily available chloropropargyl derivatives. (C) 1998 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(98)02146-7

文献信息

• Efficient total syntheses of (±)protolichesterinic acid and (±)rocellaric acid via tungsten-π-allyl complexes
  作者：Ming-Jung Chen、Rai-Shung Liu

  DOI：10.1016/s0040-4039(98)02146-7

  日期：1998.12

  Total syntheses of racemic protolichesterinic acid (1) and rocellaric add (2) were achieved with the use of tungsten-pi-allyl complex in the key step. In this synthetic route, compounds 1 and 2 were prepared in four and six steps respectively starting from readily available chloropropargyl derivatives. (C) 1998 Elsevier Science Ltd. All rights reserved.