2-Piperidin-4-yl-2H-pyrazol-3-ylamine | 957478-21-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: 2-Piperidin-4-yl-2H-pyrazol-3-ylamine
• 英文别名: 2-piperidin-4-ylpyrazol-3-amine
• CAS: 957478-21-6
• 化学式: C₈H₁₄N₄
• mdl: MFCD06011101
• 分子量: 166.22
• InChiKey: ASLYKKYZWBQKLZ-UHFFFAOYSA-N

物化性质

• 沸点：
  355.5±32.0 °C(Predicted)
• 密度：
  1.37±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -0.1
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.625
• 拓扑面积：
  55.9
• 氢给体数：
  2
• 氢受体数：
  3

安全信息

• 危险等级：
  IRRITANT

文献信息

• SUBSTITUTED PYRAZOLE COMPOUNDS AS SERINE PROTEASE INHIBITORS
  申请人：VERSEON CORPORATION

  公开号：US20200109132A1

  公开（公告）日：2020-04-09

  There are provided inter alia multisubstituted aromatic compounds useful for the inhibition of thrombin and/or kallikrein, which compounds include substituted pyrazolyl. There are additionally provided pharmaceutical compositions. There are additionally provided methods of treating and preventing certain diseases or disorders, which diseases or disorders are amenable to treatment or prevention by the inhibition of thrombin and/or kallikrein.