Trimethyl-((E)-octa-3,7-dien-1-ynyl)-silane | 182816-98-4

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 英文名称: Trimethyl-((E)-octa-3,7-dien-1-ynyl)-silane
• 英文别名: trimethyl-[(3E)-octa-3,7-dien-1-ynyl]silane
• CAS: 182816-98-4
• 化学式: C₁₁H₁₈Si
• 分子量: 178.349
• InChiKey: AINXJERVYNCFDW-CMDGGOBGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.39
• 重原子数：
  12.0
• 可旋转键数：
  3.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  0.0
• 氢给体数：
  0.0
• 氢受体数：
  0.0

反应信息

• 作为反应物：
  描述：

  Trimethyl-((E)-octa-3,7-dien-1-ynyl)-silane 在 copper diacetate 、 potassium carbonate 作用下， 以 吡啶 、 甲醇 为溶剂， 以95%的产率得到(5E,11E)-1,5,11,15-hexadecatetraen-7,9-diyne
  参考文献：
  名称：

  A straightforward synthesis of symmetrical polyendiynes by dimerization reactions of silyl derivatives

  摘要：

  A straightforward synthesis of polyendiynes is described. The method is based upon a simple dimerization reaction of silylated enynes in the presence of copper salts. A variety of polyunsaturated compounds have been obtained in high yields and with high retention of configuration. (C) 1998 Elsevier Science S.A. All rights reserved.

  DOI：

  10.1016/s0022-328x(98)00724-4
• 作为产物：
  描述：

  3-Butenylmagnesium bromide 、 Trimethyl-((E)-4-phenylsulfanyl-but-3-en-1-ynyl)-silane 在 1,2-双(二苯基膦)乙烷氯化镍 作用下， 以 四氢呋喃 为溶剂， 反应 15.0h， 以75%的产率得到Trimethyl-((E)-octa-3,7-dien-1-ynyl)-silane
  参考文献：
  名称：

  A straightforward synthesis of symmetrical polyendiynes by dimerization reactions of silyl derivatives

  摘要：

  A straightforward synthesis of polyendiynes is described. The method is based upon a simple dimerization reaction of silylated enynes in the presence of copper salts. A variety of polyunsaturated compounds have been obtained in high yields and with high retention of configuration. (C) 1998 Elsevier Science S.A. All rights reserved.

  DOI：

  10.1016/s0022-328x(98)00724-4

文献信息

• Intermolecular carbolithiation of silylated enynes
  作者：Edwige Lorthiois、Ilane Marek、Christophe Meyer、Jean F. Normant

  DOI：10.1016/s0040-4039(96)01447-5

  日期：1996.9

  The presence of a trimethylsilyl group on the terminal sp carbon of an enyne promotes a very efficient carbolithiation of the C=C double bond leading to a propargylic-allenic lithium derivative, which in rum is converted to a single allenic zinc derivative. Copyright (C) 1996 Elsevier Science Ltd
• A straightforward synthesis of symmetrical polyendiynes by dimerization reactions of silyl derivatives
  作者：Francesco Babudri、Vito Fiandanese、Giuseppe Marchese、Angela Punzi

  DOI：10.1016/s0022-328x(98)00724-4

  日期：1998.9

  A straightforward synthesis of polyendiynes is described. The method is based upon a simple dimerization reaction of silylated enynes in the presence of copper salts. A variety of polyunsaturated compounds have been obtained in high yields and with high retention of configuration. (C) 1998 Elsevier Science S.A. All rights reserved.