(4-Ethylphenyl)-[4-[3-[(3-methoxyphenyl)methyl]-1,2,4-thiadiazol-5-yl]-2-methylpiperazin-1-yl]methanone

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 英文名称: (4-Ethylphenyl)-[4-[3-[(3-methoxyphenyl)methyl]-1,2,4-thiadiazol-5-yl]-2-methylpiperazin-1-yl]methanone
• 化学式: C₂₄H₂₈N₄O₂S
• 分子量: 436.6
• InChiKey: IEZOOEHMEWHFJE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  31
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  86.8
• 氢给体数：
  0
• 氢受体数：
  6

文献信息

• Cement admixture and production method thereof
  申请人：——

  公开号：US20040260011A1

  公开（公告）日：2004-12-23

  It is an object of the present invention, which has been made in view of the above-mentioned state of the art, to provide a cement admixture capable of improving the water-reducing ability of cement compositions and the like and enhancing the strength and durability of hardened products produced therefrom and further capable of adjusting the viscosity of such compositions so as to facilitate the works at the sites of handling the same, as well as a method of producing such cement additive. A cement admixture comprising a polycarboxylic acid polymer and a nitrogen atom-containing compound having non-amide bond, wherein the mass ratio (A/B) between the mass (A) of said polycarboxylic acid polymer and the mass (B) of said nitrogen atom-containing compound having non-amide bond satisfies the relation 200>(A/B)>1.

  鉴于上述技术现状，本发明的目的是提供一种水泥外加剂，该水泥外加剂能够提高水 泥组合物和类似物的减水能力，并增强由其生产的硬化产品的强度和耐久性，还能调节这 类组合物的粘度，以便于现场处理这些组合物，本发明还提供了生产这种水泥外加剂的方 法。 一种水泥外加剂，由聚羧酸聚合物和具有非酰胺键的含氮原子化合物组成，其中所述聚羧酸聚合物的质量（A）与所述具有非酰胺键的含氮原子化合物的质量（B）之间的质量比（A/B）满足 200>（A/B）>1 的关系。
• THIADIAZOLE DERIVATIVES FOR THE TREATMENT OF NEURO DEGENERATIVE DISEASES
  申请人：NV Remynd

  公开号：EP1981504A2

  公开（公告）日：2008-10-22
• THIADIAZOLE DERIVATIVES FOR THE TREATMENT OF NEURO-DEGENERATIVE DISEASES
  申请人：NV Remynd

  公开号：EP2094677A1

  公开（公告）日：2009-09-02
• THIADIAZOLE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES
  申请人：GRIFFIOEN Gerard

  公开号：US20090054410A1

  公开（公告）日：2009-02-26

  This invention provides specifically substituted 1,2,4-thiadiazole derivatives for use in the treatment of an α-synucleopathy such as Parkinson's disease, diffuse Lewy body disease, traumatic brain injury, amyotrophic lateral sclerosis, Niemann-Pick disease, Hallervorden-Spatz syndrome, Down syndrome, neuroaxonal dystrophy, multiple system atrophy and Alzheimer's disease. This invention also provides various methods for producing such substituted 1,2,4-thiadiazole derivatives.
• US7662884B2
  申请人：——

  公开号：US7662884B2

  公开（公告）日：2010-02-16