N-(2-piperazin-1-ylethyl)butan-1-amine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 英文名称: N-(2-piperazin-1-ylethyl)butan-1-amine
• 化学式: C₁₀H₂₃N₃
• 分子量: 185.31
• InChiKey: VNQBJSITJXUQIO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  13
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  27.3
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• Biaryltriazole inhibitors of macrophage migration inhibitory factor
  申请人：YALE UNIVERSITY

  公开号：US10968198B2

  公开（公告）日：2021-04-06

  The present disclosure describes biaryl triazole compounds, as well as their compositions and methods of use. The compounds inhibit the activity of macrophage migration inhibitory factor and are useful for the treatment of diseases, e.g., inflammatory diseases and cancer.

  本公开介绍了双芳基三唑化合物及其组合物和使用方法。这些化合物抑制巨噬细胞迁移抑制因子的活性，可用于治疗疾病，如炎症性疾病和癌症。
• BIARYLTRIAZOLE INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR
  申请人：YALE UNIVERSITY

  公开号：US20190276425A1

  公开（公告）日：2019-09-12

  The present disclosure describes biaryl triazole compounds, as well as their compositions and methods of use. The compounds inhibit the activity of macrophage migration inhibitory factor and are useful for the treatment of diseases, e.g., inflammatory diseases and cancer.