1-[4-(4-Piperazin-1-ylphenyl)phenyl]piperazine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 英文名称: 1-[4-(4-Piperazin-1-ylphenyl)phenyl]piperazine
• 化学式: C₂₀H₂₆N₄
• 分子量: 322.4
• InChiKey: CQYNTHPQWHNHTL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  24
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  30.5
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• COMPOUNDS AND METHODS FOR TREATING MALARIA
  申请人：Cellceutix Corporation

  公开号：US20150094294A1

  公开（公告）日：2015-04-02

  The present disclosure provides compounds, specifically pyrimidin-4,6-dicarboxylic acid amide derivatives, or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing said compounds. Also provided are methods for treating a mammal having malaria, or killing or inhibiting the growth of a Plasmodium species, comprising administering to said mammal or contacting said Plasmodium species with, an effective amount of a pyrimidin- 4,6 -dicarboxylic acid amide derivative.
• [EN] COMPOUNDS AND METHODS FOR TREATING MALARIA<br/>[FR] COMPOSÉS ET PROCÉDÉS PERMETTANT DE TRAITER LE PALUDISME
  申请人：POLYMEDIX INC

  公开号：WO2013130738A1

  公开（公告）日：2013-09-06

  The present disclosure provides compounds, specifically pyrimidin-4,6-dicarboxylic acid amide derivatives, or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing said compounds. Also provided are methods for treating a mammal having malaria, or killing or inhibiting the growth of a Plasmodium species, comprising administering to said mammal or contacting said Plasmodium species with, an effective amount of a pyrimidin-4,6-dicarboxylic acid amide derivative.