(S)-1-Trityloxy-hex-5-en-3-ol | 262299-52-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 三苯基化合物
• 英文名称: (S)-1-Trityloxy-hex-5-en-3-ol
• 英文别名: (3S)-1-(Triphenylmethoxy)hex-5-EN-3-OL；(3S)-1-trityloxyhex-5-en-3-ol
• CAS: 262299-52-5
• 化学式: C₂₅H₂₆O₂
• 分子量: 358.48
• InChiKey: HPCIROFWHAFUAW-DEOSSOPVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  27
• 可旋转键数：
  9
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  (S)-1-Trityloxy-hex-5-en-3-ol 在 sodium periodate 、 四氧化锇 作用下， 以 乙醚 、 水 、 叔丁醇 为溶剂， 反应 4.0h， 生成 (-)-(3R,5S)-1-(trityloxy)oct-7-ene-3,5-diol
  参考文献：
  名称：

  Enantioselective Synthesis of syn- and anti-1,3-Diols via Allyltitanation of Unprotected β-Hydroxyaldehydes

  摘要：

  [GRAPHICS]syn or anti-1,3-diols units were synthesized with excellent diastereomeric excess from unprotected chiral beta-hydroxyaldehydes by using an enantioselective allyltitanation.

  DOI：

  10.1021/ol991349y
• 作为产物：
  描述：

  3-(triphenylmethyloxy)propionaldehyde 、 alkaline earth salt of/the/ methylsulfuric acid 以 乙醚 为溶剂， 生成 (R)-1-Trityloxy-hex-5-en-3-ol 、 (S)-1-Trityloxy-hex-5-en-3-ol
  参考文献：
  名称：

  Enantioselective Synthesis of syn- and anti-1,3-Diols via Allyltitanation of Unprotected β-Hydroxyaldehydes

  摘要：

  [GRAPHICS]syn or anti-1,3-diols units were synthesized with excellent diastereomeric excess from unprotected chiral beta-hydroxyaldehydes by using an enantioselective allyltitanation.

  DOI：

  10.1021/ol991349y

文献信息

• Cross-metathesis reaction. Generation of highly functionalized olefins from unsaturated alcohols
  作者：Janine Cossy、Samir BouzBouz、Amir H Hoveyda

  DOI：10.1016/s0022-328x(01)01125-1

  日期：2001.9

  A cross-metathesis reaction was achieved between acid- and base-sensitive functionalized olefins and electron-deficient olefins or allylsilane by using the recyclable ruthenium catalyst V at room temperature. The cross-metathesis products are isolated in moderate to good yield. Ratios of E and Z cross-metathesis products depend upon substituents on the electron-deficient coupling partner.

  通过在室温下使用可循环使用的钌催化剂V，在酸敏感型和碱敏感型官能化烯烃与缺电子烯烃或烯丙基硅烷之间实现了交叉复分解反应。交叉复分解产物以中等至良好的产率分离。E和Z交叉复分解产物的比例取决于电子不足的偶联配偶体上的取代基。
• Enantioselective Synthesis of <i>syn</i>- and <i>anti-</i>1,3-Diols via Allyltitanation of Unprotected β-Hydroxyaldehydes
  作者：Samir BouzBouz、Janine Cossy

  DOI：10.1021/ol991349y

  日期：2000.2.1

  [GRAPHICS]syn or anti-1,3-diols units were synthesized with excellent diastereomeric excess from unprotected chiral beta-hydroxyaldehydes by using an enantioselective allyltitanation.