3-Phenyl-4-(2-phenylethyl)piperazin-2-one | 5368-24-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 英文名称: 3-Phenyl-4-(2-phenylethyl)piperazin-2-one
• CAS: 5368-24-1
• 化学式: C₁₈H₂₀N₂O
• 分子量: 280.4
• InChiKey: PWCWFEULDOSSJE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.28
• 拓扑面积：
  32.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• [EN] A PROCESS FOR PREPARING 1-METHYL-3-PHENYLPIPERAZINE<br/>[FR] PROCEDE DE PREPARATION DE 1-METHYL-3-PHENYLPIPERAZINE
  申请人：AUROBINDO PHARMA LTD

  公开号：WO2004106309A1

  公开（公告）日：2004-12-09

  The present invention describes an industrially advantageous process to prepare highly pure 1-Methyl-3-phenylpiperazine of formula (I), that makes use of a novel piperazine derivative, 4-Benzyl-1-methyl-2-oxo-3-phenylpiperazine, represented by formula (II), 1-Methyl-3-phenylpiperazine is a useful intermediate in the preparation of antidepressant Mirtazapine.