1-vinyl-piperazine | 45590-53-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 英文名称: 1-vinyl-piperazine
• 英文别名: 1-Vinyl-piperazin；vinylpiperazine；Vinylpiperazin；1-ethenylpiperazine
• CAS: 45590-53-2
• 化学式: C₆H₁₂N₂
• mdl: MFCD19218123
• 分子量: 112.175
• InChiKey: DCRYNQTXGUTACA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  8
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.666
• 拓扑面积：
  15.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  1-(2-bromo-ethyl)-piperazine; dihydrobromide 生成 1-vinyl-piperazine 、 alkaline earth salt of/the/ methylsulfuric acid
  参考文献：
  名称：

  1,4-Diazabicyclo[2.2.2]octanes and 1,5-Diazabicyclo[3.2.2]nonanes from Piperazines and Homopiperazines

  摘要：

  DOI：

  10.1021/ja01633a057

文献信息

• Asymmetric Catalytic Hydrogenation of Prochiral Ketones and Aldehydes
  申请人：Spindler Felix

  公开号：US20090105481A1

  公开（公告）日：2009-04-23

  Process for stereoselective hydrogenation by reacting racemic aldehydes or ketones having a stereogenic carbon atom in the position relative to the C(O) group and containing the structural element —(O)C—C—CH— by means of hydrogen in the presence of a base and a ruthenium complex containing a bidentate ligand having coordinating P and N atoms, a monophosphine ligand and anionic and/or uncharged ligands as homogeneous catalyst, with the charge being balanced by one or two monovalent acid anions or a divalent acid anion when uncharged ligands are present.

  通过在碱和含有具有配位P和N原子的双齿配体、单膦配体和阴离子和/或无电荷配体的钌配合物的存在下，通过氢气作用于相对于C(O)基团位置上含有立体异构碳原子和结构元素—(O)C—C—CH—的外消旋醛或酮，进行立体选择性加氢的过程，其中当存在无电荷配体时，通过一个或两个一价酸阳离子或二价酸阴离子平衡电荷。
• [EN] ARYL HETEROBICYCLIC COMPOUNDS AS KV1.3 POTASSIUM SHAKER CHANNEL BLOCKERS<br/>[FR] COMPOSÉS HÉTÉROCYCLIQUES ARYLÉS EN TANT QUE BLOQUEURS DU CANAL POTASSIQUE SHAKER KV1.3
  申请人：DE SHAW RES LLC

  公开号：WO2021071832A1

  公开（公告）日：2021-04-15

  A compound of Formula (I), or a pharmaceutically acceptable salt thereof, is described, where the substituents are as defined herein. Pharmaceutical compositions including the same and method of using the same are also described.

  描述了化合物式(I)或其药用可接受的盐，其中取代基如本文所定义。还描述了包括该化合物的药物组合物以及使用该化合物的方法。
• ELECTROCHEMICAL DEVICE HAVING ELECTROLYTE INCLUDING DISILOXANE
  申请人：West Robert C.

  公开号：US20120115041A1

  公开（公告）日：2012-05-10

  One example of the disiloxanes include a backbone with a first silicon and a second silicon. The first silicon is linked to a first substituent selected from a group consisting of: a first side chain that includes a cyclic carbonate moiety; a first side chain that includes a poly(alkylene oxide) moiety; and a first cross link links the disiloxane to a second siloxane and that includes a poly(alkylene oxide) moiety. In some instance, the second silicon is linked to a second substituent selected from a group consisting of: a second side chain that includes a cyclic carbonate moiety, and a second side chain that includes a poly(alkylene oxide) moiety.

  一种二硅氧烷的例子包括具有第一硅和第二硅的骨架。第一硅与来自以下组的第一取代基相连接：包括环碳酸酯基的第一侧链；包括聚（烷基氧）基团的第一侧链；和第一交联将二硅氧烷连接到第二硅氧烷并包括聚（烷基氧）基团。在某些情况下，第二硅与来自以下组的第二取代基相连接：包括环碳酸酯基的第二侧链和包括聚（烷基氧）基团的第二侧链。
• INHIBITION OF HDAC2 TO PROMOTE MEMORY
  申请人：Tsai Li-Huei

  公开号：US20120101147A1

  公开（公告）日：2012-04-26

  The invention relates to methods and products for enhancing and improving recovery of lost memories. In particular the methods are accomplished by inhibiting HDAC2 and or selectively inhibiting HDAC1/2 or HDAC1/2/3.

  该发明涉及用于增强和改善丢失记忆恢复的方法和产品。具体来说，这些方法通过抑制HDAC2和/或选择性地抑制HDAC1/2或HDAC1/2/3来实现。
• BENZOTRIAZOLE COMPOUND
  申请人：MIYOSHI OIL & FAT CO.,LTD.

  公开号：US20200325107A1

  公开（公告）日：2020-10-15

  Provided is a benzotriazole compound that efficiently absorbs ray having a long wavelength of 360-400 nm, i) having excellent solubility in a monomer of a resin raw material, being dissolvable at a high concentration, polymerizing at excellent reactivity, and yielding a high-molecular-weight resin member and a transparent resin member, or ii) having exceptional heat resistance. This benzotriazole compound is represented by formula (I), where at least one of R 1 -R 9 is represented by formula (i-1), (where R 10 and R11 are hydrocarbon groups, etc., and R 12 is represented by formula (i-2) or formula (i-3) (in formula (i-2), A 1 represents a divalent group selected from nitrogen-Containing groups, oxygen-containing groups, sulfur-containing groups, phosphorus-containing groups, and phenylene groups, and R 12a -R 12c and X represent hydrocarbon groups, etc.; and in formula (i-3), A 2 represents a divalent group selected from nitrogen-containing groups, oxygen-containing groups, sulfur-containing groups, and phosphorus-containing groups, and X a and X b represent hydrocarbon groups, etc.)).

  提供了一种苯并三唑化合物，能够高效吸收波长在360-400纳米之间的射线，i）在树脂原料的单体中具有优良的溶解性，能够以高浓度溶解，具有优异的反应性进行聚合，形成高分子量树脂成员和透明树脂成员，或者ii）具有异常的耐热性。该苯并三唑化合物由式（I）表示，其中R1-R9中至少一个由式（i-1）表示，（其中R10和R11为碳氢基团等，R12由式（i-2）或式（i-3）表示（在式（i-2）中，A1表示从氮含基团、氧含基团、硫含基团、磷含基团和苯基团中选择的二价基团，R12a-R12c和X表示碳氢基团等；在式（i-3）中，A2表示从氮含基团、氧含基团、硫含基团和磷含基团中选择的二价基团，Xa和Xb表示碳氢基团等）。