8-(4-(2,5-dimethylbenzyl)piperazin-1-yl)-7-ethyl-3-methyl-3,7-dihydro-1H-purine-2,6-dione

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 英文名称: 8-(4-(2,5-dimethylbenzyl)piperazin-1-yl)-7-ethyl-3-methyl-3,7-dihydro-1H-purine-2,6-dione
• 英文别名: 8-(4-(2,5-dimethylbenzyl)piperazin-1-yl)-7-ethyl-3-methyl-1H-purine-2,6(3H,7H)-dione；8-[4-[(2,5-dimethylphenyl)methyl]piperazin-1-yl]-7-ethyl-3-methylpurine-2,6-dione
• 化学式: C₂₁H₂₈N₆O₂
• 分子量: 396.492
• InChiKey: HMCQFAWIWBZYBG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  29
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.48
• 拓扑面积：
  73.7
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• XANTHINE ANALOGS AS POTENT ANTI-WEST NILE VIRAL AGENTS
  申请人：Southern Research Institute

  公开号：US20200399271A1

  公开（公告）日：2020-12-24

  The present disclosure is concerned with xanthine analogs, methods of making xanthine analogs, and methods of treating West Nile virus using these analogs. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

  本公开涉及黄嘌呤类似物，制备黄嘌呤类似物的方法，以及使用这些类似物治疗西尼罗河病毒的方法。本摘要旨在作为特定领域搜索的扫描工具，不打算限制本发明。