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    —— (E)-3-[4-(difluoromethoxy)-3-ethoxyphenyl]-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile —— C19H20F2N4O2
    (E)-3-[4-(difluoromethoxy)-3-ethoxyphenyl]-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile
    —— (E)-3-[4-[ethyl(2-hydroxyethyl)amino]-2-methylphenyl]-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile —— C21H27N5O
    (E)-3-[4-[ethyl(2-hydroxyethyl)amino]-2-methylphenyl]-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile
    —— (E)-3-(3-ethoxy-4-phenylmethoxyphenyl)-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile —— C25H26N4O2
    (E)-3-(3-ethoxy-4-phenylmethoxyphenyl)-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile
    —— (E)-N-(2-chlorophenyl)-2-cyano-3-(3-methoxy-4-propoxyphenyl)prop-2-enamide —— C20H19ClN2O3
    (E)-N-(2-chlorophenyl)-2-cyano-3-(3-methoxy-4-propoxyphenyl)prop-2-enamide
    —— (E)-3-(4-piperidin-1-ylphenyl)-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile —— C21H25N5
    (E)-3-(4-piperidin-1-ylphenyl)-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile
    —— (E)-2-cyano-3-(3,4-dimethoxyphenyl)-N-naphthalen-1-ylprop-2-enamide —— C22H18N2O3
    (E)-2-cyano-3-(3,4-dimethoxyphenyl)-N-naphthalen-1-ylprop-2-enamide
    —— (E)-2-cyano-N-(4-ethylphenyl)-3-[3-(trifluoromethyl)phenyl]prop-2-enamide —— C19H15F3N2O
    (E)-2-cyano-N-(4-ethylphenyl)-3-[3-(trifluoromethyl)phenyl]prop-2-enamide
    —— ethyl 5-[[2-[(1R,2S,6R,7S)-3,5-dioxo-4-azatricyclo[5.2.1.02,6]dec-8-en-4-yl]acetyl]amino]-3-methylthiophene-2-carboxylate —— C19H20N2O5S
    ethyl 5-[[2-[(1R,2S,6R,7S)-3,5-dioxo-4-azatricyclo[5.2.1.02,6]dec-8-en-4-yl]acetyl]amino]-3-methylthiophene-2-carboxylate
    —— (E)-N-(2-chlorophenyl)-2-cyano-3-(6-methoxynaphthalen-2-yl)prop-2-enamide —— C21H15ClN2O2
    (E)-N-(2-chlorophenyl)-2-cyano-3-(6-methoxynaphthalen-2-yl)prop-2-enamide
    —— (E)-2-cyano-3-[4-[2-hydroxyethyl(methyl)amino]phenyl]-N-naphthalen-1-ylprop-2-enamide —— C23H21N3O2
    (E)-2-cyano-3-[4-[2-hydroxyethyl(methyl)amino]phenyl]-N-naphthalen-1-ylprop-2-enamide
    —— (E)-3-[5-(2-bromophenyl)furan-2-yl]-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile —— C20H17BrN4O
    (E)-3-[5-(2-bromophenyl)furan-2-yl]-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile
    —— (E)-3-[2-(4-chlorophenyl)-1,3-thiazol-4-yl]-2-cyano-N-(3-ethoxypropyl)prop-2-enamide —— C18H18ClN3O2S
    (E)-3-[2-(4-chlorophenyl)-1,3-thiazol-4-yl]-2-cyano-N-(3-ethoxypropyl)prop-2-enamide
    —— (E)-3-(2-ethoxyphenyl)-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile —— C18H20N4O
    (E)-3-(2-ethoxyphenyl)-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile
    —— (E)-N-(2-chlorophenyl)-2-cyano-3-(3,4-dichlorophenyl)prop-2-enamide —— C16H9Cl3N2O
    (E)-N-(2-chlorophenyl)-2-cyano-3-(3,4-dichlorophenyl)prop-2-enamide
    —— Ethyl 4-[3-(2-methylphenyl)-4-oxoquinazolin-2-yl]sulfanylbutanoate —— C21H22N2O3S
    Ethyl 4-[3-(2-methylphenyl)-4-oxoquinazolin-2-yl]sulfanylbutanoate
    —— (E)-2-cyano-3-[2,5-dimethyl-1-[3-(trifluoromethyl)phenyl]pyrrol-3-yl]-N-prop-2-enylprop-2-enamide —— C20H18F3N3O
    (E)-2-cyano-3-[2,5-dimethyl-1-[3-(trifluoromethyl)phenyl]pyrrol-3-yl]-N-prop-2-enylprop-2-enamide
    —— (E)-3-[5-(difluoromethylsulfanylmethyl)furan-2-yl]-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile —— C16H16F2N4OS
    (E)-3-[5-(difluoromethylsulfanylmethyl)furan-2-yl]-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile
    —— (E)-N-(2-chlorophenyl)-2-cyano-3-(3-phenylmethoxyphenyl)prop-2-enamide —— C23H17ClN2O2
    (E)-N-(2-chlorophenyl)-2-cyano-3-(3-phenylmethoxyphenyl)prop-2-enamide
    —— (E)-2-cyano-3-(3-ethoxy-4-methoxyphenyl)-N-naphthalen-1-ylprop-2-enamide —— C23H20N2O3
    (E)-2-cyano-3-(3-ethoxy-4-methoxyphenyl)-N-naphthalen-1-ylprop-2-enamide
    —— (E)-2-cyano-N-(4-ethylphenyl)-3-(4-methyl-3-nitrophenyl)prop-2-enamide —— C19H17N3O3
    (E)-2-cyano-N-(4-ethylphenyl)-3-(4-methyl-3-nitrophenyl)prop-2-enamide
    —— (E)-2-cyano-3-[1-(4-ethoxyphenyl)-2,5-dimethylpyrrol-3-yl]-N-prop-2-enylprop-2-enamide —— C21H23N3O2
    (E)-2-cyano-3-[1-(4-ethoxyphenyl)-2,5-dimethylpyrrol-3-yl]-N-prop-2-enylprop-2-enamide
    —— (E)-N-(2-chlorophenyl)-2-cyano-3-(3,4-dimethoxyphenyl)prop-2-enamide —— C18H15ClN2O3
    (E)-N-(2-chlorophenyl)-2-cyano-3-(3,4-dimethoxyphenyl)prop-2-enamide
    —— (E)-3-[2,5-dimethyl-1-(2-methylpropyl)pyrrol-3-yl]-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile —— C20H27N5
    (E)-3-[2,5-dimethyl-1-(2-methylpropyl)pyrrol-3-yl]-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile
    —— (E)-3-(3-ethoxy-4-propoxyphenyl)-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile —— C21H26N4O2
    (E)-3-(3-ethoxy-4-propoxyphenyl)-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile
    —— (E)-3-(4-bromo-3-nitrophenyl)-N-(2-chlorophenyl)-2-cyanoprop-2-enamide —— C16H9BrClN3O3
    (E)-3-(4-bromo-3-nitrophenyl)-N-(2-chlorophenyl)-2-cyanoprop-2-enamide
    —— (E)-3-(4-butoxy-3-ethoxyphenyl)-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile —— C22H28N4O2
    (E)-3-(4-butoxy-3-ethoxyphenyl)-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile
    —— (E)-3-(4-propan-2-ylphenyl)-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile —— C19H22N4
    (E)-3-(4-propan-2-ylphenyl)-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile
    —— (E)-N-(2-chlorophenyl)-2-cyano-3-[2,5-dimethyl-1-(2-methylpropyl)pyrrol-3-yl]prop-2-enamide —— C20H22ClN3O
    (E)-N-(2-chlorophenyl)-2-cyano-3-[2,5-dimethyl-1-(2-methylpropyl)pyrrol-3-yl]prop-2-enamide
    —— (E)-3-(2-chloro-8-methylquinolin-3-yl)-N-(2-chlorophenyl)-2-cyanoprop-2-enamide —— C20H13Cl2N3O
    (E)-3-(2-chloro-8-methylquinolin-3-yl)-N-(2-chlorophenyl)-2-cyanoprop-2-enamide
    —— (E)-N-(2-chlorophenyl)-2-cyano-3-[5-(difluoromethylsulfanylmethyl)furan-2-yl]prop-2-enamide —— C16H11ClF2N2O2S
    (E)-N-(2-chlorophenyl)-2-cyano-3-[5-(difluoromethylsulfanylmethyl)furan-2-yl]prop-2-enamide
    —— Ethyl 4-[3-(3,4-dimethylphenyl)-4-oxoquinazolin-2-yl]sulfanylbutanoate —— C22H24N2O3S
    Ethyl 4-[3-(3,4-dimethylphenyl)-4-oxoquinazolin-2-yl]sulfanylbutanoate
    —— (E)-N-(2-chlorophenyl)-2-cyano-3-[4-(difluoromethoxy)-3-ethoxyphenyl]prop-2-enamide —— C19H15ClF2N2O3
    (E)-N-(2-chlorophenyl)-2-cyano-3-[4-(difluoromethoxy)-3-ethoxyphenyl]prop-2-enamide
    —— (E)-3-[3-(difluoromethoxy)-4-methoxyphenyl]-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile —— C18H18F2N4O2
    (E)-3-[3-(difluoromethoxy)-4-methoxyphenyl]-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile
    —— (E)-3-(6-bromo-1,3-benzodioxol-5-yl)-2-cyano-N-(2-phenylethyl)prop-2-enamide —— C19H15BrN2O3
    (E)-3-(6-bromo-1,3-benzodioxol-5-yl)-2-cyano-N-(2-phenylethyl)prop-2-enamide
    —— (E)-3-(3-ethoxy-2-methoxyphenyl)-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile —— C19H22N4O2
    (E)-3-(3-ethoxy-2-methoxyphenyl)-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile
    —— Ethyl 3-methyl-1-[6-[(3-methylphenyl)methylsulfanyl]pyrimidin-4-yl]pyrazole-4-carboxylate —— C19H20N4O2S
    Ethyl 3-methyl-1-[6-[(3-methylphenyl)methylsulfanyl]pyrimidin-4-yl]pyrazole-4-carboxylate
    —— (E)-3-(3-bromophenyl)-N-(2-chlorophenyl)-2-cyanoprop-2-enamide —— C16H10BrClN2O
    (E)-3-(3-bromophenyl)-N-(2-chlorophenyl)-2-cyanoprop-2-enamide
    —— (E)-3-[4-(dipropylamino)phenyl]-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile —— C22H29N5
    (E)-3-[4-(dipropylamino)phenyl]-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile
    —— (E)-3-(3-chlorophenyl)-2-cyano-N-phenethylacrylamide —— C18H15ClN2O
    (E)-3-(3-chlorophenyl)-2-cyano-N-phenethylacrylamide
    —— (E)-3-(2-chloro-6-fluorophenyl)-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile —— C16H14ClFN4
    (E)-3-(2-chloro-6-fluorophenyl)-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile
    —— (E)-2-cyano-3-[5-(difluoromethylsulfanylmethyl)furan-2-yl]-N-(2-phenylethyl)prop-2-enamide —— C18H16F2N2O2S
    (E)-2-cyano-3-[5-(difluoromethylsulfanylmethyl)furan-2-yl]-N-(2-phenylethyl)prop-2-enamide
    —— (E)-3-[1-(4-chlorophenyl)-2,5-dimethylpyrrol-3-yl]-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile —— C22H22ClN5
    (E)-3-[1-(4-chlorophenyl)-2,5-dimethylpyrrol-3-yl]-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile
    —— (E)-2-cyano-3-(4-methylphenyl)-N-(2-phenoxyphenyl)prop-2-enamide —— C23H18N2O2
    (E)-2-cyano-3-(4-methylphenyl)-N-(2-phenoxyphenyl)prop-2-enamide
    —— (E)-2-cyano-N-(2-phenoxyphenyl)-3-pyridin-4-ylprop-2-enamide —— C21H15N3O2
    (E)-2-cyano-N-(2-phenoxyphenyl)-3-pyridin-4-ylprop-2-enamide
    —— (E)-3-(2-chloro-7-methylquinolin-3-yl)-2-cyano-N-(2-phenylethyl)prop-2-enamide —— C22H18ClN3O
    (E)-3-(2-chloro-7-methylquinolin-3-yl)-2-cyano-N-(2-phenylethyl)prop-2-enamide
    —— (E)-3-(2-chloro-6-fluorophenyl)-2-cyano-N-(2-phenylethyl)prop-2-enamide —— C18H14ClFN2O
    (E)-3-(2-chloro-6-fluorophenyl)-2-cyano-N-(2-phenylethyl)prop-2-enamide
    —— (E)-3-[4-[(4-fluorophenyl)methoxy]-3-methoxyphenyl]-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile —— C24H23FN4O2
    (E)-3-[4-[(4-fluorophenyl)methoxy]-3-methoxyphenyl]-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile
    —— (E)-2-cyano-3-(1H-indol-3-yl)-N-(2-phenoxyphenyl)prop-2-enamide —— C24H17N3O2
    (E)-2-cyano-3-(1H-indol-3-yl)-N-(2-phenoxyphenyl)prop-2-enamide
    —— (E)-3-[3-chloro-4-(difluoromethoxy)-5-methoxyphenyl]-2-cyano-N-(2-phenylethyl)prop-2-enamide —— C20H17ClF2N2O3
    (E)-3-[3-chloro-4-(difluoromethoxy)-5-methoxyphenyl]-2-cyano-N-(2-phenylethyl)prop-2-enamide
    —— (E)-3-(3-bromo-4-methoxyphenyl)-2-cyano-N-(2-phenylethyl)prop-2-enamide —— C19H17BrN2O2
    (E)-3-(3-bromo-4-methoxyphenyl)-2-cyano-N-(2-phenylethyl)prop-2-enamide