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    首页 分子通 按分子结构分类 有机化合物 有机杂环化合物 三唑并嘧啶类

    三唑并嘧啶类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— (7R)-5-methyl-N-(2-methylphenyl)-2-[(3-methylphenyl)methylsulfanyl]-7-(4-methylsulfanylphenyl)-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C29H29N5OS2
    (7R)-5-methyl-N-(2-methylphenyl)-2-[(3-methylphenyl)methylsulfanyl]-7-(4-methylsulfanylphenyl)-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— (7S)-5-methyl-N-(2-methylphenyl)-2-[(3-methylphenyl)methylsulfanyl]-7-phenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C28H27N5OS
    (7S)-5-methyl-N-(2-methylphenyl)-2-[(3-methylphenyl)methylsulfanyl]-7-phenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— (7S)-2-[(4-chlorophenyl)methylsulfanyl]-5-methyl-N,7-diphenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C26H22ClN5OS
    (7S)-2-[(4-chlorophenyl)methylsulfanyl]-5-methyl-N,7-diphenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— (7S)-N-(2,4-dimethylphenyl)-2-[(2,5-dimethylphenyl)methylsulfanyl]-5-methyl-7-phenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C30H31N5OS
    (7S)-N-(2,4-dimethylphenyl)-2-[(2,5-dimethylphenyl)methylsulfanyl]-5-methyl-7-phenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— (7R)-2-ethylsulfanyl-5-methyl-N-(2-methylphenyl)-7-pyridin-3-yl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C21H22N6OS
    (7R)-2-ethylsulfanyl-5-methyl-N-(2-methylphenyl)-7-pyridin-3-yl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— (7S)-N-(2-methoxyphenyl)-7-(4-methoxyphenyl)-5-methyl-2-[(3-methylphenyl)methylsulfanyl]-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C29H29N5O3S
    (7S)-N-(2-methoxyphenyl)-7-(4-methoxyphenyl)-5-methyl-2-[(3-methylphenyl)methylsulfanyl]-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— (7S)-7-(3-chlorophenyl)-5-methyl-N-(2-methylphenyl)-2-[(3-methylphenyl)methylsulfanyl]-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C28H26ClN5OS
    (7S)-7-(3-chlorophenyl)-5-methyl-N-(2-methylphenyl)-2-[(3-methylphenyl)methylsulfanyl]-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— (7R)-7-(4-methoxyphenyl)-5-methyl-N-(2-methylphenyl)-2-[(3-methylphenyl)methylsulfanyl]-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C29H29N5O2S
    (7R)-7-(4-methoxyphenyl)-5-methyl-N-(2-methylphenyl)-2-[(3-methylphenyl)methylsulfanyl]-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— 5,7-bis(4-ethoxyphenyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine —— C21H25N5O2
    5,7-bis(4-ethoxyphenyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine
    —— (7S)-5-methyl-N-(2-methylphenyl)-2-[(3-methylphenyl)methylsulfanyl]-7-thiophen-2-yl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C26H25N5OS2
    (7S)-5-methyl-N-(2-methylphenyl)-2-[(3-methylphenyl)methylsulfanyl]-7-thiophen-2-yl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— (7S)-2-ethylsulfanyl-7-(2-fluorophenyl)-N-(2-methoxyphenyl)-5-methyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C22H22FN5O2S
    (7S)-2-ethylsulfanyl-7-(2-fluorophenyl)-N-(2-methoxyphenyl)-5-methyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— (7R)-2-[(2,5-dimethylphenyl)methylsulfanyl]-5-methyl-N,7-diphenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C28H27N5OS
    (7R)-2-[(2,5-dimethylphenyl)methylsulfanyl]-5-methyl-N,7-diphenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— (7S)-2-ethylsulfanyl-5-methyl-N-(2-methylphenyl)-7-pyridin-3-yl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C21H22N6OS
    (7S)-2-ethylsulfanyl-5-methyl-N-(2-methylphenyl)-7-pyridin-3-yl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— (7S)-7-(2-chlorophenyl)-2-ethylsulfanyl-N-(2-methoxyphenyl)-5-methyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C22H22ClN5O2S
    (7S)-7-(2-chlorophenyl)-2-ethylsulfanyl-N-(2-methoxyphenyl)-5-methyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— (7S)-2-benzylsulfanyl-N-(2,4-dimethylphenyl)-5-methyl-7-thiophen-2-yl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C26H25N5OS2
    (7S)-2-benzylsulfanyl-N-(2,4-dimethylphenyl)-5-methyl-7-thiophen-2-yl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— (7R)-2-[(2,5-dimethylphenyl)methylsulfanyl]-5-methyl-N-phenyl-7-thiophen-2-yl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C26H25N5OS2
    (7R)-2-[(2,5-dimethylphenyl)methylsulfanyl]-5-methyl-N-phenyl-7-thiophen-2-yl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— 5-(4-bromophenyl)-7-(2,6-dichlorophenyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidine —— C17H13BrCl2N4
    5-(4-bromophenyl)-7-(2,6-dichlorophenyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidine
    —— (7R)-2-benzylsulfanyl-N-(2,4-dimethylphenyl)-7-(4-methoxyphenyl)-5-methyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C29H29N5O2S
    (7R)-2-benzylsulfanyl-N-(2,4-dimethylphenyl)-7-(4-methoxyphenyl)-5-methyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— (7S)-2-[(2,5-dimethylphenyl)methylsulfanyl]-5-methyl-N-phenyl-7-thiophen-2-yl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C26H25N5OS2
    (7S)-2-[(2,5-dimethylphenyl)methylsulfanyl]-5-methyl-N-phenyl-7-thiophen-2-yl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— (7S)-7-(4-chlorophenyl)-5-methyl-N-(2-methylphenyl)-2-[(3-methylphenyl)methylsulfanyl]-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C28H26ClN5OS
    (7S)-7-(4-chlorophenyl)-5-methyl-N-(2-methylphenyl)-2-[(3-methylphenyl)methylsulfanyl]-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— (7R)-7-(3-chlorophenyl)-2-[(2,5-dimethylphenyl)methylsulfanyl]-5-methyl-N-phenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C28H26ClN5OS
    (7R)-7-(3-chlorophenyl)-2-[(2,5-dimethylphenyl)methylsulfanyl]-5-methyl-N-phenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— (7R)-2-benzylsulfanyl-7-(3-chlorophenyl)-5-methyl-N-phenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C26H22ClN5OS
    (7R)-2-benzylsulfanyl-7-(3-chlorophenyl)-5-methyl-N-phenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— (7R)-N-(2-methoxyphenyl)-5-methyl-2-[(3-methylphenyl)methylsulfanyl]-7-phenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C28H27N5O2S
    (7R)-N-(2-methoxyphenyl)-5-methyl-2-[(3-methylphenyl)methylsulfanyl]-7-phenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— (7R)-N-(2-methoxyphenyl)-5-methyl-2-[(3-methylphenyl)methylsulfanyl]-7-thiophen-2-yl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C26H25N5O2S2
    (7R)-N-(2-methoxyphenyl)-5-methyl-2-[(3-methylphenyl)methylsulfanyl]-7-thiophen-2-yl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— 4-[(7R)-2-[(2,5-dimethylphenyl)methylsulfanyl]-5-methyl-6-(phenylcarbamoyl)-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]benzoic acid —— C29H27N5O3S
    4-[(7R)-2-[(2,5-dimethylphenyl)methylsulfanyl]-5-methyl-6-(phenylcarbamoyl)-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]benzoic acid
    —— (7S)-2-benzylsulfanyl-N-(2,4-dimethylphenyl)-5-methyl-7-phenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C28H27N5OS
    (7S)-2-benzylsulfanyl-N-(2,4-dimethylphenyl)-5-methyl-7-phenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— (7S)-2-benzylsulfanyl-N-(2,4-dimethylphenyl)-7-(4-fluorophenyl)-5-methyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C28H26FN5OS
    (7S)-2-benzylsulfanyl-N-(2,4-dimethylphenyl)-7-(4-fluorophenyl)-5-methyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— (7S)-7-(3-chlorophenyl)-2-ethylsulfanyl-N-(2-methoxyphenyl)-5-methyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C22H22ClN5O2S
    (7S)-7-(3-chlorophenyl)-2-ethylsulfanyl-N-(2-methoxyphenyl)-5-methyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— (7R)-7-(4-methoxyphenyl)-2-[(3-methoxyphenyl)methylsulfanyl]-5-methyl-N-phenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C28H27N5O3S
    (7R)-7-(4-methoxyphenyl)-2-[(3-methoxyphenyl)methylsulfanyl]-5-methyl-N-phenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— (7R)-2-[(3-methoxyphenyl)methylsulfanyl]-5-methyl-7-(4-methylphenyl)-N-phenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C28H27N5O2S
    (7R)-2-[(3-methoxyphenyl)methylsulfanyl]-5-methyl-7-(4-methylphenyl)-N-phenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— (7S)-7-(4-methoxyphenyl)-2-[(3-methoxyphenyl)methylsulfanyl]-5-methyl-N-phenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C28H27N5O3S
    (7S)-7-(4-methoxyphenyl)-2-[(3-methoxyphenyl)methylsulfanyl]-5-methyl-N-phenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— (7R)-2-[(2,5-dimethylphenyl)methylsulfanyl]-5-methyl-7-(4-methylphenyl)-N-phenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C29H29N5OS
    (7R)-2-[(2,5-dimethylphenyl)methylsulfanyl]-5-methyl-7-(4-methylphenyl)-N-phenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— (7S)-N-(2-methoxyphenyl)-5-methyl-2-[(3-methylphenyl)methylsulfanyl]-7-thiophen-2-yl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C26H25N5O2S2
    (7S)-N-(2-methoxyphenyl)-5-methyl-2-[(3-methylphenyl)methylsulfanyl]-7-thiophen-2-yl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— (7S)-2-benzylsulfanyl-N-(2,4-dimethylphenyl)-7-(4-hydroxyphenyl)-5-methyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C28H27N5O2S
    (7S)-2-benzylsulfanyl-N-(2,4-dimethylphenyl)-7-(4-hydroxyphenyl)-5-methyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— (7S)-7-(4-fluorophenyl)-5-methyl-N-(2-methylphenyl)-2-[(3-methylphenyl)methylsulfanyl]-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C28H26FN5OS
    (7S)-7-(4-fluorophenyl)-5-methyl-N-(2-methylphenyl)-2-[(3-methylphenyl)methylsulfanyl]-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— (7R)-2-benzylsulfanyl-N-(2,4-dimethylphenyl)-7-(4-ethoxyphenyl)-5-methyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C30H31N5O2S
    (7R)-2-benzylsulfanyl-N-(2,4-dimethylphenyl)-7-(4-ethoxyphenyl)-5-methyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— (7S)-2-ethylsulfanyl-N-(2-methoxyphenyl)-5-methyl-7-(4-methylphenyl)-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C23H25N5O2S
    (7S)-2-ethylsulfanyl-N-(2-methoxyphenyl)-5-methyl-7-(4-methylphenyl)-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— (7S)-2-[(4-chlorophenyl)methylsulfanyl]-5-methyl-N-(2-methylphenyl)-7-phenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C27H24ClN5OS
    (7S)-2-[(4-chlorophenyl)methylsulfanyl]-5-methyl-N-(2-methylphenyl)-7-phenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— (7S)-2-[(2,5-dimethylphenyl)methylsulfanyl]-5-methyl-N,7-diphenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C28H27N5OS
    (7S)-2-[(2,5-dimethylphenyl)methylsulfanyl]-5-methyl-N,7-diphenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— (7R)-7-(4-fluorophenyl)-5-methyl-N-(2-methylphenyl)-2-[(3-methylphenyl)methylsulfanyl]-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C28H26FN5OS
    (7R)-7-(4-fluorophenyl)-5-methyl-N-(2-methylphenyl)-2-[(3-methylphenyl)methylsulfanyl]-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— (7R)-2-[(3-methoxyphenyl)methylsulfanyl]-5-methyl-7-(2-methylphenyl)-N-phenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C28H27N5O2S
    (7R)-2-[(3-methoxyphenyl)methylsulfanyl]-5-methyl-7-(2-methylphenyl)-N-phenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— (7R)-7-(2-chlorophenyl)-2-ethylsulfanyl-N-(2-methoxyphenyl)-5-methyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C22H22ClN5O2S
    (7R)-7-(2-chlorophenyl)-2-ethylsulfanyl-N-(2-methoxyphenyl)-5-methyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— 4-[(7S)-2-[(2,5-dimethylphenyl)methylsulfanyl]-5-methyl-6-(phenylcarbamoyl)-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]benzoic acid —— C29H27N5O3S
    4-[(7S)-2-[(2,5-dimethylphenyl)methylsulfanyl]-5-methyl-6-(phenylcarbamoyl)-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]benzoic acid
    —— (7R)-2-benzylsulfanyl-5-methyl-7-(4-methylphenyl)-N-phenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C27H25N5OS
    (7R)-2-benzylsulfanyl-5-methyl-7-(4-methylphenyl)-N-phenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— methyl 2-(2-chlorophenyl)-7-(4-ethoxyphenyl)-5-methyl-1,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate —— C22H21ClN4O3
    methyl 2-(2-chlorophenyl)-7-(4-ethoxyphenyl)-5-methyl-1,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate
    —— ethyl 5-(methoxymethyl)-7-(2,3,5-trimethoxyphenyl)-1,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate —— C19H24N4O6
    ethyl 5-(methoxymethyl)-7-(2,3,5-trimethoxyphenyl)-1,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate
    —— 5-chloro-N-(7-hydroxy-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)thiophene-2-sulfonamide —— C10H8ClN5O3S2
    5-chloro-N-(7-hydroxy-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)thiophene-2-sulfonamide
    —— 10,10-dimethyl-3-(methylsulfanyl)-5-(propan-2-ylsulfanyl)-10,11-dihydro-8H-pyrano[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[4,3-c]pyrimidine —— C16H20N4OS3
    10,10-dimethyl-3-(methylsulfanyl)-5-(propan-2-ylsulfanyl)-10,11-dihydro-8H-pyrano[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[4,3-c]pyrimidine
    —— N-(5-methyl-7-phenyl-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-2-phenoxyacetamide —— C20H21N5O2
    N-(5-methyl-7-phenyl-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-2-phenoxyacetamide
    —— 7-[4-(2-oxo-2-pyrrolidin-1-ylethoxy)phenyl]-6,7-dihydro-1H-[1,2,4]triazolo[1,5-a]pyrimidin-5-one —— C17H19N5O3
    7-[4-(2-oxo-2-pyrrolidin-1-ylethoxy)phenyl]-6,7-dihydro-1H-[1,2,4]triazolo[1,5-a]pyrimidin-5-one