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    首页 分子通 按分子结构分类 有机化合物 有机杂环化合物 三唑并嘧啶类

    三唑并嘧啶类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 1-[(3R)-3-[(5S,7R)-7-(difluoromethyl)-4,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-methylpropan-1-one —— C15H23F2N5O
    1-[(3R)-3-[(5S,7R)-7-(difluoromethyl)-4,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-methylpropan-1-one
    —— 1-[(3S)-3-[(5S,7R)-7-(difluoromethyl)-4,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-methylpropan-1-one —— C15H23F2N5O
    1-[(3S)-3-[(5S,7R)-7-(difluoromethyl)-4,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-methylpropan-1-one
    —— 2-(4-Tert-butylphenoxy)-1-[4-[7-(difluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]ethanone —— C23H27F2N5O2
    2-(4-Tert-butylphenoxy)-1-[4-[7-(difluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]ethanone
    —— 1-((3,4-dichlorobenzyl)thio)-7-isopropyl-4-(p-tolyl)-6,7-dihydro-4H-pyrano[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[4,3-a]pyrimidin-5(9H)-one —— C27H24Cl2N4O2S2
    1-((3,4-dichlorobenzyl)thio)-7-isopropyl-4-(p-tolyl)-6,7-dihydro-4H-pyrano[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[4,3-a]pyrimidin-5(9H)-one
    —— 2-(4-tert-butylphenoxy)-1-[(3R)-3-[(5S,7R)-7-(difluoromethyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]ethanone —— C23H31F2N5O2
    2-(4-tert-butylphenoxy)-1-[(3R)-3-[(5S,7R)-7-(difluoromethyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]ethanone
    —— 2-(4-tert-butylphenoxy)-1-[(3S)-3-[(5S,7R)-7-(difluoromethyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]ethanone —— C23H31F2N5O2
    2-(4-tert-butylphenoxy)-1-[(3S)-3-[(5S,7R)-7-(difluoromethyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]ethanone
    —— (7-tert-butyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl)-[(3R)-3-[(4-fluorophenoxy)methyl]piperidin-1-yl]methanone —— C22H26FN5O2
    (7-tert-butyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl)-[(3R)-3-[(4-fluorophenoxy)methyl]piperidin-1-yl]methanone
    —— (7-tert-butyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl)-[(3S)-3-[(4-fluorophenoxy)methyl]piperidin-1-yl]methanone —— C22H26FN5O2
    (7-tert-butyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl)-[(3S)-3-[(4-fluorophenoxy)methyl]piperidin-1-yl]methanone
    —— (2R)-1-[(3S)-3-[(5S,7R)-7-(difluoromethyl)-4,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(2-fluorophenoxy)propan-1-one —— C20H24F3N5O2
    (2R)-1-[(3S)-3-[(5S,7R)-7-(difluoromethyl)-4,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(2-fluorophenoxy)propan-1-one
    —— (2R)-1-[(3R)-3-[(5S,7R)-7-(difluoromethyl)-4,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(2-fluorophenoxy)propan-1-one —— C20H24F3N5O2
    (2R)-1-[(3R)-3-[(5S,7R)-7-(difluoromethyl)-4,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(2-fluorophenoxy)propan-1-one
    —— (2R)-1-[(3S)-3-[(5S,7R)-7-(difluoromethyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(2-methoxyphenoxy)propan-1-one —— C21H27F2N5O3
    (2R)-1-[(3S)-3-[(5S,7R)-7-(difluoromethyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(2-methoxyphenoxy)propan-1-one
    —— (2R)-2-(4-fluorophenoxy)-1-[(3R)-3-[(5S,7R)-7-(trifluoromethyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]propan-1-one —— C20H23F4N5O2
    (2R)-2-(4-fluorophenoxy)-1-[(3R)-3-[(5S,7R)-7-(trifluoromethyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]propan-1-one
    —— (2S)-2-(4-fluorophenoxy)-1-[(3R)-3-[(5S,7R)-7-(trifluoromethyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]propan-1-one —— C20H23F4N5O2
    (2S)-2-(4-fluorophenoxy)-1-[(3R)-3-[(5S,7R)-7-(trifluoromethyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]propan-1-one
    —— (2R)-2-(4-fluorophenoxy)-1-[(3S)-3-[(5S,7R)-7-(trifluoromethyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]propan-1-one —— C20H23F4N5O2
    (2R)-2-(4-fluorophenoxy)-1-[(3S)-3-[(5S,7R)-7-(trifluoromethyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]propan-1-one
    —— (2S)-1-[(3S)-3-[(5S,7R)-7-(difluoromethyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(2-methoxyphenoxy)propan-1-one —— C21H27F2N5O3
    (2S)-1-[(3S)-3-[(5S,7R)-7-(difluoromethyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(2-methoxyphenoxy)propan-1-one
    —— (2S)-1-[(3S)-3-[(5S,7R)-7-(difluoromethyl)-4,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(2-fluorophenoxy)propan-1-one —— C20H24F3N5O2
    (2S)-1-[(3S)-3-[(5S,7R)-7-(difluoromethyl)-4,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(2-fluorophenoxy)propan-1-one
    —— (2S)-2-(4-fluorophenoxy)-1-[(3S)-3-[(5S,7R)-7-(trifluoromethyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]propan-1-one —— C20H23F4N5O2
    (2S)-2-(4-fluorophenoxy)-1-[(3S)-3-[(5S,7R)-7-(trifluoromethyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]propan-1-one
    —— (2S)-1-[(3R)-3-[(5S,7R)-7-(difluoromethyl)-4,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(2-fluorophenoxy)propan-1-one —— C20H24F3N5O2
    (2S)-1-[(3R)-3-[(5S,7R)-7-(difluoromethyl)-4,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(2-fluorophenoxy)propan-1-one
    —— (2R)-1-[(3R)-3-[(5S,7R)-7-(difluoromethyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(2-methoxyphenoxy)propan-1-one —— C21H27F2N5O3
    (2R)-1-[(3R)-3-[(5S,7R)-7-(difluoromethyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(2-methoxyphenoxy)propan-1-one
    —— (2S)-1-[(3S)-3-[(5S,7R)-7-(difluoromethyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(3-methoxyphenoxy)propan-1-one —— C21H27F2N5O3
    (2S)-1-[(3S)-3-[(5S,7R)-7-(difluoromethyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(3-methoxyphenoxy)propan-1-one
    —— (2S)-1-[(3R)-3-[(5S,7R)-7-(difluoromethyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(2-methoxyphenoxy)propan-1-one —— C21H27F2N5O3
    (2S)-1-[(3R)-3-[(5S,7R)-7-(difluoromethyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(2-methoxyphenoxy)propan-1-one
    —— (2R)-1-[(3S)-3-[(5S,7R)-7-(difluoromethyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(3-methoxyphenoxy)propan-1-one —— C21H27F2N5O3
    (2R)-1-[(3S)-3-[(5S,7R)-7-(difluoromethyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(3-methoxyphenoxy)propan-1-one
    —— (2R)-1-[4-[7-(difluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(2-methoxyphenoxy)propan-1-one —— C21H23F2N5O3
    (2R)-1-[4-[7-(difluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(2-methoxyphenoxy)propan-1-one
    —— (2S)-2-(2-methoxyphenoxy)-1-[4-[7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]propan-1-one —— C21H22F3N5O3
    (2S)-2-(2-methoxyphenoxy)-1-[4-[7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]propan-1-one
    —— (2S)-1-[4-[7-(difluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(3-methoxyphenoxy)propan-1-one —— C21H23F2N5O3
    (2S)-1-[4-[7-(difluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(3-methoxyphenoxy)propan-1-one
    —— N-[(2,3-dichlorophenyl)methyl]-5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine —— C14H13Cl2N5
    N-[(2,3-dichlorophenyl)methyl]-5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine
    —— 5-(4-methoxyphenyl)-7-(3,4,5-trimethoxyphenyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidine —— C21H24N4O4
    5-(4-methoxyphenyl)-7-(3,4,5-trimethoxyphenyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidine
    —— 7-(2,4,5-trimethoxyphenyl)-6,7-dihydro-1H-[1,2,4]triazolo[1,5-a]pyrimidin-5-one —— C14H16N4O4
    7-(2,4,5-trimethoxyphenyl)-6,7-dihydro-1H-[1,2,4]triazolo[1,5-a]pyrimidin-5-one
    —— 2-methoxyethyl 7-[4-(difluoromethoxy)phenyl]-5-methyl-1,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate —— C17H18F2N4O4
    2-methoxyethyl 7-[4-(difluoromethoxy)phenyl]-5-methyl-1,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate
    —— 7-(3-bromophenyl)-5-(4-ethylphenyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine —— C19H20BrN5
    7-(3-bromophenyl)-5-(4-ethylphenyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine
    —— 7-Isopropyl-1-[(1-methyl-2-morpholino-2-oxoethyl)sulfanyl]-4-(4-methylphenyl)-6,9-dihydro-7H-pyrano[4',3':4,5]thieno[3,2-E][1,2,4]triazolo[4,3-A]pyrimidin-5(4H)-one —— C27H31N5O4S2
    7-Isopropyl-1-[(1-methyl-2-morpholino-2-oxoethyl)sulfanyl]-4-(4-methylphenyl)-6,9-dihydro-7H-pyrano[4',3':4,5]thieno[3,2-E][1,2,4]triazolo[4,3-A]pyrimidin-5(4H)-one
    —— N-(3,4-dimethylphenyl)-2-[2-(5-oxo-6,7-dihydro-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)phenoxy]acetamide —— C21H21N5O3
    N-(3,4-dimethylphenyl)-2-[2-(5-oxo-6,7-dihydro-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)phenoxy]acetamide
    —— 10-ethyl-5-hydrazinyl-10-methyl-10,11-dihydro-8H-pyrano[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine —— C13H16N6OS
    10-ethyl-5-hydrazinyl-10-methyl-10,11-dihydro-8H-pyrano[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine
    —— 2-[(12,12-dimethyl-12,13-dihydro-10H-pyrano[4',3':4,5]thieno[3,2-e]bis[1,2,4]triazolo[4,3-a:1',5'-c]pyrimidin-7-yl)sulfanyl]-1-(piperidin-1-yl)ethanone —— C20H23N7O2S2
    2-[(12,12-dimethyl-12,13-dihydro-10H-pyrano[4',3':4,5]thieno[3,2-e]bis[1,2,4]triazolo[4,3-a:1',5'-c]pyrimidin-7-yl)sulfanyl]-1-(piperidin-1-yl)ethanone
    —— N-(3-cyanophenyl)-2-[(5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)sulfanyl]propanamide —— C17H16N6OS
    N-(3-cyanophenyl)-2-[(5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)sulfanyl]propanamide
    —— 2-[(5,7-Dimethyl-[1,2,4]triazolo[4,3-a]pyrimidin-3-yl)sulfanyl]-1-[1-(2-methoxyethyl)-2,5-dimethylpyrrol-3-yl]ethanone —— C18H23N5O2S
    2-[(5,7-Dimethyl-[1,2,4]triazolo[4,3-a]pyrimidin-3-yl)sulfanyl]-1-[1-(2-methoxyethyl)-2,5-dimethylpyrrol-3-yl]ethanone
    —— (5S,7R)-7-(difluoromethyl)-5-[(3R)-1-[(E)-2-methyl-3-phenylprop-2-enyl]piperidin-3-yl]-4,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidine —— C21H27F2N5
    (5S,7R)-7-(difluoromethyl)-5-[(3R)-1-[(E)-2-methyl-3-phenylprop-2-enyl]piperidin-3-yl]-4,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidine
    —— 7-(4-Nitro-phenyl)-6,7-dihydro-4H-[1,2,4]triazolo[1,5-a]pyrimidin-5-one —— C11H9N5O3
    7-(4-Nitro-phenyl)-6,7-dihydro-4H-[1,2,4]triazolo[1,5-a]pyrimidin-5-one
    —— 7-[4-[(4-chlorophenyl)methoxy]-3-ethoxyphenyl]-5-methyl-N-phenyl-1,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C28H26ClN5O3
    7-[4-[(4-chlorophenyl)methoxy]-3-ethoxyphenyl]-5-methyl-N-phenyl-1,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— 5-amino-1,6-dihydro-[1,2,3]triazolo[4,5-<i>d</i>]pyrimidine-7-thione 59886-10-1 C4H4N6S
    5-amino-1,6-dihydro-[1,2,3]triazolo[4,5-<i>d</i>]pyrimidine-7-thione
    —— 7-[3-methoxy-4-(2-oxo-2-pyrrolidin-1-ylethoxy)phenyl]-6,7-dihydro-1H-[1,2,4]triazolo[1,5-a]pyrimidin-5-one —— C18H21N5O4
    7-[3-methoxy-4-(2-oxo-2-pyrrolidin-1-ylethoxy)phenyl]-6,7-dihydro-1H-[1,2,4]triazolo[1,5-a]pyrimidin-5-one
    —— 1-((3,4-dichlorobenzyl)thio)-7-isopropyl-4-(4-methoxyphenyl)-6,7-dihydro-4H-pyrano[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[4,3-a]pyrimidin-5(9H)-one —— C27H24Cl2N4O3S2
    1-((3,4-dichlorobenzyl)thio)-7-isopropyl-4-(4-methoxyphenyl)-6,7-dihydro-4H-pyrano[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[4,3-a]pyrimidin-5(9H)-one
    —— 2-{[(4-Ethylphenyl)methyl]amino}-5-propyl-4H,7H-[1,2,4]triazolo[1,5-A]pyrimidin-7-one —— C17H21N5O
    2-{[(4-Ethylphenyl)methyl]amino}-5-propyl-4H,7H-[1,2,4]triazolo[1,5-A]pyrimidin-7-one
    —— [(7,7-dimethyl-5-oxo-4-phenyl-4,5,6,9-tetrahydro-7H-pyrano[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[4,3-a]pyrimidin-1-yl)sulfanyl]acetonitrile —— C20H17N5O2S2
    [(7,7-dimethyl-5-oxo-4-phenyl-4,5,6,9-tetrahydro-7H-pyrano[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[4,3-a]pyrimidin-1-yl)sulfanyl]acetonitrile
    —— 2-[[4-bromo-2-(5-oxo-6,7-dihydro-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)phenoxy]methyl]benzonitrile —— C19H14BrN5O2
    2-[[4-bromo-2-(5-oxo-6,7-dihydro-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)phenoxy]methyl]benzonitrile
    —— 7-[3-bromo-4-[(2-chlorophenyl)methoxy]-5-methoxyphenyl]-6,7-dihydro-1H-[1,2,4]triazolo[1,5-a]pyrimidin-5-one —— C19H16BrClN4O3
    7-[3-bromo-4-[(2-chlorophenyl)methoxy]-5-methoxyphenyl]-6,7-dihydro-1H-[1,2,4]triazolo[1,5-a]pyrimidin-5-one
    —— ethyl 2-acetamido-5-[7-(4-chlorophenyl)-2-(trifluoromethyl)-1,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]-4-methylthiophene-3-carboxylate —— C22H19ClF3N5O3S
    ethyl 2-acetamido-5-[7-(4-chlorophenyl)-2-(trifluoromethyl)-1,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]-4-methylthiophene-3-carboxylate
    —— pentyl (7S)-5-methyl-7-(2,3,4-trimethoxyphenyl)-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate —— C21H28N4O5
    pentyl (7S)-5-methyl-7-(2,3,4-trimethoxyphenyl)-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate
    —— prop-2-enyl (7S)-5-methyl-7-pyridin-3-yl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate —— C15H15N5O2
    prop-2-enyl (7S)-5-methyl-7-pyridin-3-yl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate
    —— 2-(5,7-dimethyl-2-methylsulfanyl-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)-N-[(1R)-1-(4-fluorophenyl)-2-methylpropyl]acetamide —— C20H24FN5OS
    2-(5,7-dimethyl-2-methylsulfanyl-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)-N-[(1R)-1-(4-fluorophenyl)-2-methylpropyl]acetamide