Ethyl [(cyanomethyl)sulfonyl]acetate | 1156876-76-4

• 分子结构分类: 有机化合物 - 有机硫化合物 - 磺酰类
• 英文名称: Ethyl [(cyanomethyl)sulfonyl]acetate
• 英文别名: ethyl 2-(cyanomethylsulfonyl)acetate
• CAS: 1156876-76-4
• 化学式: C₆H₉NO₄S
• 分子量: 191.208
• InChiKey: UVGYFNCNYUUFJG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  12
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  92.6
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  ethyl 2-(cyanomethylthio)acetate 在 双氧水 、 dioxide titanium 作用下， 以 乙腈 为溶剂， 反应 8.5h， 以95%的产率得到Ethyl [(cyanomethyl)sulfonyl]acetate
  参考文献：
  名称：

  TiO2 nanoparticles and Preyssler-type heteropoly acid modified nano-sized TiO2: A facile and efficient catalyst for the selective oxidation of sulfides to sulfones and sulfoxides

  摘要：

  A new and efficient synthetic method has been developed for the selective conversion of sulfides into their corresponding sulfones and sulfoxides using H2O2 in the presence of neat or Preyssler-type heteropoly acid modified nano-sized TiO2 as catalyst. respectively. The reaction was performed at room temperature with quantitative yields. The catalyst is reusable without significant loss of activity for the next oxidation reaction. (C) 2010 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.molcata.2010.03.011

文献信息

• TiO2 nanoparticles and Preyssler-type heteropoly acid modified nano-sized TiO2: A facile and efficient catalyst for the selective oxidation of sulfides to sulfones and sulfoxides
  作者：Mohammad Rahimizadeh、Ghadir Rajabzadeh、Seyed-Mola Khatami、Hossein Eshghi、Ali Shiri

  DOI：10.1016/j.molcata.2010.03.011

  日期：2010.5.17

  A new and efficient synthetic method has been developed for the selective conversion of sulfides into their corresponding sulfones and sulfoxides using H2O2 in the presence of neat or Preyssler-type heteropoly acid modified nano-sized TiO2 as catalyst. respectively. The reaction was performed at room temperature with quantitative yields. The catalyst is reusable without significant loss of activity for the next oxidation reaction. (C) 2010 Elsevier B.V. All rights reserved.