二水合硫酸钙

• 分子结构分类: 无机化合物 - 混合金属/非金属化合物 - 碱土金属氧阴离子化合物
• 中文名称: 二水合硫酸钙
• 中文别名: 接合剂；上(状)石膏；磷石膏；石膏
• 英文名称: calcium;sulfate;dihydrate
• 化学式: CaH4O6S
• 分子量: 172.17
• InChiKey: PASHVRUKOFIRIK-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  -3.37
• 重原子数：
  8
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  90.6
• 氢给体数：
  2
• 氢受体数：
  6

ADMET

毒理性

• 吸入症状

咳嗽。

Cough.

来源:ILO-WHO International Chemical Safety Cards (ICSCs)

毒理性

• 眼睛症状

红色。

Redness.

来源:ILO-WHO International Chemical Safety Cards (ICSCs)

反应信息

• 作为反应物：
  描述：

  二水合硫酸钙 以 水 为溶剂， 生成 硫酸钙半水合物
  参考文献：
  名称：

  Low embodied energy wallboards and methods of making same

  摘要：

  墙板采用的生产方法，与制造石膏墙板所需的能量相比，大大降低了能量消耗。一种新型粘合剂，其中一种实施方式包括单磷酸钾和氧化镁，并与各种填料结合使用，用于提供可控的放热反应，以创建类似于石膏板的芯材，可以用选择的材料（如回收纸张）包裹，并在传送带系统上制造，看起来和处理起来像石膏墙板，但不需要大量的能量来制造石膏墙板。所得产品可用于室内或室外应用，并具有石膏墙板的防火、隔音和其他重要性能。随着能源成本的增加，这种新型墙板的制造成本可能会比传统墙板更低。制造过程产生的温室气体排放比制造石膏墙板的过程要少得多。

  公开号：

  US20080171179A1
• 作为产物：
  描述：

  硫酸 、 calcium hydrogen phosphate 生成 二水合硫酸钙 、 磷酸
  参考文献：
  名称：

  Phosphoric acid process with high circulation rates

  摘要：

  磷酸是通过使用包括溶解浆和结晶浆的反应列，通过磷酸盐岩和硫酸的反应制备而成，该反应列在不同的硫酸盐水平下维持。高速度使用内部和间隔循环来最小化试剂浓度梯度和温度梯度，并提供适宜的结晶环境。最好是，内部循环在很大程度上是塞流，如通过引流管。

  公开号：

  US04277448A1
• 作为试剂：
  描述：

  3,4,5,6-四氟邻苯二甲酸 在 二水合硫酸钙 作用下， 以 水 为溶剂， 以to produce 2,3,4,5-tetrafluorobenzoic acid in a yield of 86.4 mole %的产率得到2,3,4,5-四氟苯甲酸
  参考文献：
  名称：

  Method for production of 2,3,4,5-tetrafluorobenzoic acid

  摘要：

  一种生产2,3,4,5-四氟苯甲酸的方法，其包括在调节至pH值为0.7至2.2的水介质中，在温度为100°C至220°C的范围内，通过脱碳3,4,5,6-四氟邻苯二甲酸来实现该生产。

  公开号：

  US04769492A1

文献信息

• Pharmaceutical preparation, method for its production as well as its use
  申请人：Heraeus Kulzer GmbH & Co. KG

  公开号：US20040067253A1

  公开（公告）日：2004-04-08

  The invention relates to hardly soluble antiphlogistic salts and antiphlogistic-antibiotic pharmaceutical preparations and their use. The hardly water soluble antiphlogistic antibiotics salts have as their cationic component one of the antibiotics gentamicin, clindamycin, neomycin, streptomycin, tetracycline, doxicyline, oxytetracycline and rolitetracycline and as their anionic component one of the antiphlogistics ibuprofen, naproxen, indomethacin, dexamethasone-21-phosphate, dexamethasone-21-sulfate, triamcinolone-21-phosphate and triamcinolone-21-sulfate. The antiphlogistic antibiotics salts are used in pharmaceutical preparations as controlled-release antibiotic/antibiotics drugs. The invention describes antiphlogistic-antibiotic pharmaceutical preparations for which mixtures in the solid state of aggregation are used, which are composed of an easily water soluble salt of gentamicin, clindamycin, neomycin, streptomycin, tetracycline, doxicycline, oxytetracycline and/or rolitetracycline and at least one easily water soluble salt of ibuprofen, naproxen, indomethacin, dexamethasone-21-phosphate, dexamethasone-21-sulfate, triamcinolone-21-phosphate and/or triamcinolone-21-sulfate and at least one inorganic and/or organic pharmaceutical adjuvant and which are used as permanent or temporary implants in the form of tablets and/or molded bodies.

  本发明涉及难溶性抗炎盐和抗炎抗生素制剂及其使用。难水溶性抗炎抗生素盐的阳离子组分为庆大霉素、林可霉素、新霉素、链霉素、四环素、多西环素、氧四环素和罗利四环素之一，阴离子组分为布洛芬、萘普生、消炎症、地塞米松-21-磷酸酯、地塞米松-21-硫酸酯、曲安奈德-21-磷酸酯和曲安奈德-21-硫酸酯之一。抗炎抗生素盐用作控制释放抗生素药物的制剂。本发明还描述了抗炎抗生素制剂，其中使用固态混合物，该混合物由庆大霉素、林可霉素、新霉素、链霉素、四环素、多西环素、氧四环素和/或罗利四环素的易水溶性盐和布洛芬、萘普生、消炎症、地塞米松-21-磷酸酯、地塞米松-21-硫酸酯、曲安奈德-21-磷酸酯和/或曲安奈德-21-硫酸酯的至少一个易水溶性盐和至少一个无机和/或有机制药助剂组成，并用作以片剂和/或成型体形式的永久或临时植入物。
• Method of reducing the solubility of calcium sulfate dihydrate in an aqueous suspension and method of making same
  申请人：——

  公开号：US20040241082A1

  公开（公告）日：2004-12-02

  The suspension of needle-shaped (acicular) calcium sulfate dihydrate particles is prepared by mixing freshly calcined calcium sulfate hemihydrate (CaSO 4 11 2?O), having an average particle size between 1 and 100 micrometers, and water in a reactor at medium to high shear rate, with either no additives or together with acids or with calcium or sulfate containing additives. The average length and width of the resulting calcium sulfate dihydrate particles are then about 5 to 35 micrometers and 1 to 5 micrometers, respectively. The calcium sulfate dihydrate particles of reduced solubility are obtained using a calcium chelating agent, with or without the addition of a weak acid. The resulting product is a suspension of calcium sulfate dihydrate particles that can be used as a filler in papermaking. The particles have a high retention and provide improved optical properties with minimal filler losses due to solubility.

  该文翻译如下：通过将新酸煅石膏半水合物（CaSO4•1/2H2O），平均粒径在1到100微米之间，与水在中高剪切速率下混合，无添加剂或与含酸、钙或硫酸盐的添加剂一起，在反应器中制备出针状（针状）硫酸钙二水合物颗粒的悬浮液。由此产生的硫酸钙二水合物颗粒的平均长度和宽度分别约为5至35微米和1至5微米。使用钙螯合剂，有或没有加入弱酸，可以获得溶解度降低的硫酸钙二水合物颗粒。得到的产品是一种硫酸钙二水合物颗粒的悬浮液，可用作造纸中的填料。这些颗粒具有高的保留能力，并提供改善的光学性能，由于溶解度的缘故，填料损失最小。
• Removal of boron from lithium chloride brine
  申请人：Foote Mineral Company

  公开号：US04261960A1

  公开（公告）日：1981-04-14

  Boron, as well as magnesium and sulfate impurities, are removed from or at least substantially reduced in a lithium containing brine to minimize lithium losses on further concentration of the brine by adding to the brine an aqueous slurry of slaked lime and a solution of calcium chloride to form a calcium borate hydrate, magnesium hydroxide and calcium sulfate dihydrate, the last named compound being precipitated and separated from the brine. On further concentration of the brine, calcium boron hydrate and magnesium hydroxide precipitate and they are also removed from the brine. In an alternate procedure, the pH of the brine is adjusted to 8.0-8.4 by addition of hydrochloric acid to form a calcium borate hydrate, which on further evaporation, is also separated from the brine. The brine is then concentrated further to recover lithium values.

  硼、镁和硫酸盐杂质从含锂卤水中去除或至少大幅减少，以最小化在进一步浓缩卤水时的锂损失，方法是向卤水中加入一种熟石灰水浆和一种氯化钙溶液，形成一种钙硼酸盐水合物、氢氧化镁和硫酸钙二水合物，最后一种化合物被沉淀并从卤水中分离。在进一步浓缩卤水时，钙硼酸盐水合物和氢氧化镁沉淀并从卤水中去除。在另一种方法中，通过加入盐酸将卤水的pH值调整为8.0-8.4，形成一种钙硼酸盐水合物，进一步蒸发后，也从卤水中分离出来。然后进一步浓缩卤水以回收锂值。
• Inorganic fibers
  申请人：Suddeutsche Kalkstickstoff-Werke Aktiengesellschaft

  公开号：US04270954A1

  公开（公告）日：1981-06-02

  The invention provides inorganic fibers based on calcium sulfate dihydrate or calcium sulfate aluminate hydrate (or their dehydration products), wherein the ratio of average length to diameter of the fibers is more than 100:1 and the length of the fibers is at least 0.2 mm; preferably the ratio of average length to diameter is 300-800:1, and the length is 0.5-6 mm.

  该发明提供了基于硫酸钙二水合物或硫酸钙铝酸盐二水合物（或其脱水产物）的无机纤维，其中纤维的平均长度与直径的比值大于100:1，且纤维长度至少为0.2毫米；最好的情况是平均长度与直径的比值为300-800:1，长度为0.5-6毫米。
• Method for manufacturing phosphoric acid and gypsum
  申请人：Pullman Incorporated

  公开号：US04059674A1

  公开（公告）日：1977-11-22

  A method of producing wet process phosphoric acid comprises reacting, in a reactor system, calcium phosphate rock particles with a mixture of recycled phosphoric and sulfuric acids, preferably supplemented with added fresh sulfuric acid, to form additional phosphoric acid and calcium sulfate dihydrate (gypsum). The reactor environment is controlled so as to avoid appreciable coating of the rock particles with calcium sulfate. A gypsum slurry is withdrawn and product phosphoric acid is separated therefrom and withdrawn from the process. The gypsum may be washed with a dilute sulfuric acid wash solution which is then added to the reactor. The gypsum is passed to a first recrystallizer wherein sulfuric acid is introduced, and the gypsum is recrystallized to hemihydrate. A slurry of the hemihydrate is passed to a second recrystallizer, wherein water obtained as described below is added and the hemihydrate is recrystallized to gypsum. The liquid component of the recrystallized gypsum slurry is separated therefrom and is employed as the above mentioned dilute sulfuric acid wash solution with, preferably, a portion being diverted to the first recrystallizer to control the solids content thereof. The recrystallized gypsum is washed with water, which is then added to the second recrystallizer as described above, and the washed gypsum is removed from the process as by-product.

  一种生产湿法磷酸的方法包括在反应器系统中，将磷酸钙岩石颗粒与再生的磷酸和硫酸混合物反应，最好加入新的硫酸，以形成额外的磷酸和硫酸钙二水合物（石膏）。反应器环境被控制，以避免岩石颗粒与硫酸钙结合。从中提取石膏浆并分离出产品磷酸，从过程中撤回。石膏可以用稀硫酸洗涤溶液清洗，然后加入反应器。石膏经过第一次重结晶器，在其中引入硫酸，石膏重结晶为半水合物。半水合物的浆料经过第二次重结晶器，在其中加入下面描述的水，并将半水合物重结晶为石膏。重结晶石膏浆的液体组分被分离出来，并用作上述稀硫酸洗涤溶液，最好将部分分流到第一次重结晶器中以控制其固体含量。重结晶石膏用水清洗，然后按上述方法加入第二次重结晶器中，洗涤石膏作为副产品从过程中移除。

表征谱图