3',7'-dihex-5-enylspiro[cyclopentane-1,9'-[3,7]-diazabicyclo[3.3.1]nonane]-2',4',6',8'-tetraone | 960506-62-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氮杂螺癸烷衍生物
• 英文名称: 3',7'-dihex-5-enylspiro[cyclopentane-1,9'-[3,7]-diazabicyclo[3.3.1]nonane]-2',4',6',8'-tetraone
• 英文别名: 3,7-Bis(hex-5-enyl)spiro[3,7-diazabicyclo[3.3.1]nonane-9,1'-cyclopentane]-2,4,6,8-tetrone；3,7-bis(hex-5-enyl)spiro[3,7-diazabicyclo[3.3.1]nonane-9,1'-cyclopentane]-2,4,6,8-tetrone
• CAS: 960506-62-1
• 化学式: C₂₃H₃₂N₂O₄
• 分子量: 400.518
• InChiKey: SRSVVNRMMJGTLI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  29
• 可旋转键数：
  10
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.65
• 拓扑面积：
  74.8
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  3',7'-dihex-5-enylspiro[cyclopentane-1,9'-[3,7]-diazabicyclo[3.3.1]nonane]-2',4',6',8'-tetraone 在 RuCl2(1,3-dimesityl-imidazolidin-2-yl)(PCy3)(=CHPh) 作用下， 以 二氯甲烷 为溶剂， 反应 0.12h， 生成 spiro[cyclopentane-1,17'-[3,14]-diazatricyclo[12.3.1.1^3,16]-8-nonadecene]-2',15',18',19'-tetraone 、 spiro[cyclopentane-1,17'-[3,14]-diazatricyclo[12.3.1.1^3,16]-8-nonadecene]-2',15',18',19'-tetraone
  参考文献：
  名称：

  Synthesis of New Tricyclic Spirobispidines via Ring Closing Metathesis Reaction

  摘要：

  New tricyclic spiro compounds based on 3,7-diazabicyclo[3.3.1]-nonane (bispidine) were synthesized by ruthenium-catalyzed ring closing metathesis reactions. The constitution of the newly formed double bond depending on the chain length and various conditions of the RCM reaction was analyzed.

  DOI：

  10.3987/com-07-11063
• 作为产物：
  描述：

  spiro[cyclopentane-1,9'-(3,7-diaza-bicyclo[3.3.1]nonane)]-2',4',6',8'-tetraone 、 6-溴-1-己烯 在 sodium hydride 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 2.5h， 以39%的产率得到3',7'-dihex-5-enylspiro[cyclopentane-1,9'-[3,7]-diazabicyclo[3.3.1]nonane]-2',4',6',8'-tetraone
  参考文献：
  名称：

  Synthesis of New Tricyclic Spirobispidines via Ring Closing Metathesis Reaction

  摘要：

  New tricyclic spiro compounds based on 3,7-diazabicyclo[3.3.1]-nonane (bispidine) were synthesized by ruthenium-catalyzed ring closing metathesis reactions. The constitution of the newly formed double bond depending on the chain length and various conditions of the RCM reaction was analyzed.

  DOI：

  10.3987/com-07-11063

文献信息

• Synthesis of New Tricyclic Spirobispidines via Ring Closing Metathesis Reaction
  作者：Christian Hametner、Daniel Dangl、Kurt Mereiter、Martina Marchetti、Johannes Fröhlich

  DOI：10.3987/com-07-11063

  日期：——

  New tricyclic spiro compounds based on 3,7-diazabicyclo[3.3.1]-nonane (bispidine) were synthesized by ruthenium-catalyzed ring closing metathesis reactions. The constitution of the newly formed double bond depending on the chain length and various conditions of the RCM reaction was analyzed.