4-azido-N,N-diphenyl-6-(1H-pyrrol-1-yl)-1,3,5-triazin-2-amine | 1135597-09-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 三嗪类
• 英文名称: 4-azido-N,N-diphenyl-6-(1H-pyrrol-1-yl)-1,3,5-triazin-2-amine
• CAS: 1135597-09-9
• 化学式: C₁₉H₁₄N₈
• 分子量: 354.374
• InChiKey: AONSSIWPDIXUMT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.07
• 重原子数：
  27.0
• 可旋转键数：
  5.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  95.6
• 氢给体数：
  0.0
• 氢受体数：
  6.0

反应信息

• 作为反应物：
  描述：

  4-azido-N,N-diphenyl-6-(1H-pyrrol-1-yl)-1,3,5-triazin-2-amine 、 三苯基膦 以 苯 为溶剂， 以87%的产率得到N,N-diphenyl-4-(1H-pyrrol-1-yl)-6-((triphenyl-l5-phosphaneylidene)amino)-1,3,5-triazin-2-amine
  参考文献：
  名称：

  三嗪类。8. 4,6-二取代的2-（1H-吡咯基）-1,3,5-三嗪的合成及一些反应

  摘要：

  We have studied the reaction of 2,5-dimethoxytetrahydrofuran with 4,6-disubstituted 2-amino-1,3,5-triazines with the aim of obtaining novel coupled polyheterocyclic systems with potential bioactivity. Reaction conditions were optimized. A series of novel 4,6-disubstituted 2-(1H-1-pyrrolyl)-sym-triazines was obtained. It was found that the product yields depended on the nature of the substituent in the 4 and 6 positions of the triazine ring and on the reaction conditions.

  DOI：

  10.1007/s10593-008-0050-4
• 作为产物：
  描述：

  2,5-二甲氧基四氢呋喃 、 6-azido-N2,N2-diphenyl-1,3,5-triazine-2,4-diamine 在 phosphorus pentoxide 作用下， 以 甲苯 为溶剂， 以93%的产率得到4-azido-N,N-diphenyl-6-(1H-pyrrol-1-yl)-1,3,5-triazin-2-amine
  参考文献：
  名称：

  三嗪类。8. 4,6-二取代的2-（1H-吡咯基）-1,3,5-三嗪的合成及一些反应

  摘要：

  We have studied the reaction of 2,5-dimethoxytetrahydrofuran with 4,6-disubstituted 2-amino-1,3,5-triazines with the aim of obtaining novel coupled polyheterocyclic systems with potential bioactivity. Reaction conditions were optimized. A series of novel 4,6-disubstituted 2-(1H-1-pyrrolyl)-sym-triazines was obtained. It was found that the product yields depended on the nature of the substituent in the 4 and 6 positions of the triazine ring and on the reaction conditions.

  DOI：

  10.1007/s10593-008-0050-4