2,3-dimethylthioxanthone | 81877-48-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 硫色烯
• 英文名称: 2,3-dimethylthioxanthone
• 英文别名: 2,3-dimethyl-9H-thioxanthen-9-one；2,3-dimethylthioxanthen-9-one
• CAS: 81877-48-7
• 化学式: C₁₅H₁₂OS
• 分子量: 240.326
• InChiKey: RVABTWZCMKSODQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  17
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  42.4
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  3,4-二甲基苯硫酚 在 硫酸 、 sodium 、 铜 作用下， 以 甲醇 为溶剂， 反应 1.08h， 生成 2,3-dimethylthioxanthone
  参考文献：
  名称：

  Dimethylthioxanthones formed by condensation of 2-mercaptobenzoic acid with o-, or m-xylene in sulfuric acid.

  摘要：

  多种二甲基取代的噻喹喔啉是通过2-巯基苯甲酸与邻-, 中-, 或对-二甲苯在硫酸中的缩合反应制备的。其中一些是新化合物（5，11，12和13）。即，从邻二甲苯中形成了1,2-二甲基（11），2,3-二甲基（12）和3,4-二甲基噻喹喔啉（13），产率分别为9.3%、37.1%和12.8%。通过相同的缩合反应，从中二甲苯和对二甲苯分别获得了2,4-二甲基噻喹喔啉（4）和1,4-二甲基噻喹喔啉（9）。根据光谱研究和与通过另一合成路径（即苯基硫代苯甲酸的环化反应）获得的认证材料的比较，确认了这些化合物的结构。

  DOI：

  10.1248/cpb.35.2545

文献信息

• Synthesis of Xanthones, Thioxanthones, and Acridones by the Coupling of Arynes and Substituted Benzoates
  作者：Jian Zhao、Richard C. Larock

  DOI：10.1021/jo0620718

  日期：2007.1.1

  The reaction of silylaryl triflates, CsF, and ortho-heteroatom-substituted benzoates affords a general and efficient way to prepare biologically interesting xanthones, thioxanthones, and acridones. This chemistry presumably proceeds by a tandem intermolecular nucleophilic coupling of the benzoate with an aryne and a subsequent intramolecular electrophilic cyclization.

  甲硅烷基芳基三氟甲磺酸酯，CsF和邻杂原子取代的苯甲酸酯的反应提供了制备生物学上有趣的氧杂蒽酮，噻吨杂蒽和a啶酮的通用且有效的方法。据推测，该化学反应是通过苯甲酸酯与芳烃的串联分子间亲核偶联和随后的分子内亲电环化而进行的。
• Light- sensitive composition
  申请人：FUJI PHOTO FILM CO., LTD.

  公开号：EP0410654A2

  公开（公告）日：1991-01-30

  A light-sensitive composition comprises a photo-­crosslinkable polymer having a photo-dimerizable unsaturated bond and a sensitizer represented by the following general formula (I): wherein R₁ and R₂ each independently represents a hydrogen atom, a substituted or unsubstituted alkyl group, a substituted or unsubstituted aryl group, a substituted or unsubstituted heterocyclic group or a substituted or unsubstituted allyl group, provided that R₁ and R₂ may form a ring together with the carbon atoms to which they are attached; n represents 0, 1 or 2; and G₁ and G₂ each independently represents a hydrogen atom, a cyano group, a substituted or unsubstituted alkoxycarbonyl group, a substituted or unsubstituted aryloxycarbonyl group, a substituted or unsubstituted acyl group, a substituted or unsubstituted arylcarbonyl group, an alkylthio group, an arylthio group, an alkylsulfonyl group, an arylsulfonyl group or a fluoroalkylsulfonyl group, provided that G₁ and G₂ do not represent a hydrogen atom simultaneously and that G₁ and G₂ may form a ring comprising a non-metallic atom and the carbon atoms to which they are attached. According to the present invention, the sensitivity of the light-sensitive composition is greatly improved by the use of the above sensitizer.

  一种光敏组合物包括具有可光二聚的不饱和键的可光交联聚合物和由以下通式 (I) 代表的敏化剂： 其中 R₁ 和 R₂ 各自独立地代表氢原子、取代或未取代的烷基、取代或未取代的芳基、取代或未取代的杂环基团或取代或未取代的烯丙基，条件是 R₁ 和 R₂ 可与它们所连接的碳原子一起形成环；n 代表 0、1 或 2；G₁和 G₂ 各自独立地代表氢原子、氰基、取代或未取代的烷氧羰基、取代或未取代的芳氧羰基、取代或未取代的酰基、取代或未取代的芳羰基、烷硫基烷硫基、芳硫基、烷基磺酰基、芳基磺酰基或氟烷基磺酰基，条件是 G₁ 和 G₂ 不同时代表一个氢原子，并且 G₁ 和 G₂ 可以形成一个由非金属原子和它们所连接的碳原子组成的环。根据本发明，使用上述敏化剂可大大提高光敏组合物的灵敏度。
• SURFACE-MODIFIED METAL AND METHOD FOR MODIFYING METAL SURFACE
  申请人：Sumitomo Rubber Industries, Ltd.

  公开号：EP2949782A1

  公开（公告）日：2015-12-02

  The present invention provides surface-modified metals such as metal medical devices, e.g., guide wires, syringe needles, and metal tubes in medical devices or equipment, in which a lubricant layer is firmly bonded to the surface to impart lubricity to the surface, and further to improve the durability of the lubricant layer on the surface, thereby reducing deterioration of sliding properties, as well as methods for modifying a metal surface. The present invention relates to a surface-modified metal having a surface at least partially treated by polymerizing a monomer in the presence of a hydrogen abstraction type photopolymerization initiator.

  本发明提供了表面改性金属，例如金属医疗器械，如医疗器械或设备中的导丝、注射器针头和金属管，其中润滑剂层牢固地粘合在表面上，以赋予表面润滑性，并进一步提高表面润滑剂层的耐久性，从而减少滑动性能的恶化，以及改性金属表面的方法。本发明涉及一种表面改性金属，其表面至少部分是通过在氢抽离型光聚合引发剂存在下聚合单体而处理的。
• SURFACE MODIFICATION METHOD FOR THREE-DIMENSIONAL OBJECT AND SYRINGE GASKET
  申请人：Sumitomo Rubber Industries, Ltd.

  公开号：EP2998343A1

  公开（公告）日：2016-03-23

  The present invention provides methods of modifying the surfaces of a plurality of three-dimensional objects at the same time to provide good sliding properties, good durability after repeated sliding, good sealing properties, and the like, and also provides gaskets for syringes obtained by such methods. The present invention relates to a method for modifying the surfaces of a plurality of three-dimensional objects including: a step 1 of immersing a plurality of three-dimensional objects in a photopolymerizable monomer-containing liquid; and a step 2 of polymerizing the photopolymerizable monomer by photoirradiation while rotating a vessel containing the plurality of three-dimensional objects and the photopolymerizable monomer-containing liquid, to grow polymer chains on the surfaces of the plurality of three-dimensional objects.

  本发明提供了同时对多个三维物体的表面进行改性的方法，以提供良好的滑动性能、反复滑动后的良好耐久性、良好的密封性能等，还提供了通过这种方法获得的注射器用垫圈。本发明涉及一种改性多个三维物体表面的方法，包括：步骤 1：将多个三维物体浸入含光聚合单体的液体中；步骤 2：在旋转装有多个三维物体和含光聚合单体的液体的容器时，通过光照射使光聚合单体聚合，从而在多个三维物体的表面生长聚合物链。
• Surface-modified metal and method for modifying metal surface
  申请人：SUMITOMO RUBBER INDUSTRIES, LTD.

  公开号：US10835644B2

  公开（公告）日：2020-11-17

  The present invention provides surface-modified metals such as metal medical devices, e.g., guide wires, syringe needles, and metal tubes in medical devices or equipment, in which a lubricant layer is firmly bonded to the surface to impart lubricity to the surface, and further to improve the durability of the lubricant layer on the surface, thereby reducing deterioration of sliding properties, as well as methods for modifying a metal surface. The present invention relates to a surface-modified metal having a surface at least partially treated by polymerizing a monomer in the presence of a hydrogen abstraction type photopolymerization initiator.

  本发明提供了表面改性金属，如金属医疗器械，例如医疗器械或设备中的导丝、注射器针头和金属管，其中润滑剂层牢固地粘合在表面上，以赋予表面润滑性，并进一步提高表面润滑剂层的耐久性，从而减少滑动性能的恶化，还提供了改性金属表面的方法。本发明涉及一种表面改性金属，其表面至少部分是通过在氢抽离型光聚合引发剂存在下聚合单体而处理的。