bis-(dimethylaluminium)-1,3-propenedithiolate | 56110-67-9

• 分子结构分类: 有机化合物 - 有机盐 - 有机金属盐
• 英文名称: bis-(dimethylaluminium)-1,3-propenedithiolate
• 英文别名: bis(dimethylaluminium)propane-1,3-dithiolate；Bis(dimethylaluminium)-1,3-propandithiolat；3-Dimethylalumanylsulfanylpropylsulfanyl(dimethyl)alumane
• CAS: 56110-67-9
• 化学式: C₇H₁₈Al₂S₂
• 分子量: 220.315
• InChiKey: UCMDDHMGZNPJME-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  3.35
• 重原子数：
  11
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  50.6
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  bis-(dimethylaluminium)-1,3-propenedithiolate 、 methyl 5-azidohexanoate 以 二氯甲烷 、 甲苯 为溶剂， 反应 48.0h， 以66%的产率得到2-(4-azidopent-1-ylidene)-1,3-dithiane
  参考文献：
  名称：

  Ketene-S,S-acetals as 1,3-dipolarophiles towards azides. A new synthetic entry into cyclic amino acids

  摘要：

  Intramolecular azide cycloaddition reactions of ketene-S,S-acetals proceed to give a reactive imine as the initially-formed intermediate and this mechanism is supported by thermolysis of (18) which gave the stable imine (22). N-Acylation of this intermediate leads to cyclic variants of 2-amino ketene-S,S-acetals (20, 24, 27), which can be viewed as masked alpha-amino acids, and reduction leads to the corresponding dithiane (21, 25, 29a). Both systems have been converted to cyclic alpha-amino acids and the scope, in terms of the ring sizes available, and the limitations of this intramolecular cycloaddition process are discussed.

  DOI：

  10.1016/s0040-4020(01)90368-0

文献信息

• The ketene thioacetal group as a cationic cyclization terminator.
  作者：A.Richard Chamberlin、John Y.L. Chung

  DOI：10.1016/s0040-4039(00)87412-2

  日期：1982.1

  A cationic cyclization to the pyrrolizidine ring system is reported in which a ketene thioacetal group serves as an efficient terminator for 5-membered ring formation. (±)-Supinidine is prepared using this methodology.

  据报道，阳离子环化到吡咯烷核环系统中，其中烯酮硫缩醛基团是形成五元环的有效终止剂。（±）-Supinidine是使用这种方法制备的。
• Moss, William O.; Jones, Annette C.; Wisedale, Richard, Journal of the Chemical Society. Perkin transactions I, 1992, # 20, p. 2615 - 2624
  作者：Moss, William O.、Jones, Annette C.、Wisedale, Richard、Mahon, Mary F.、Molloy, Kieran C.、et al.

  DOI：——

  日期：——
• CHAMBERLIN, A. R.;CHUNG, J. Y. L., TETRAHEDRON LETT., 1982, 23, N 26, 2619-2622
  作者：CHAMBERLIN, A. R.、CHUNG, J. Y. L.

  DOI：——

  日期：——
• COREY E. J.; KOZIWSKI A. P., TETRAHEDRON LETT. <TELE-AY>, 1975, NO 11, 925-928
  作者：COREY E. J.、 KOZIWSKI A. P.

  DOI：——

  日期：——
• XAPA MACAXAPY; HARA MASAHARU, KAGAKU TO KOGE, KAGAKU TO KOGUO, CHEM AND CHEM. IND. <KAKT-AF>, 1975, 28,+
  作者：XAPA MACAXAPY、 HARA MASAHARU

  DOI：——

  日期：——