N,N-dimethyl-4-((2-(trifluoromethyl)phenyl)diazenyl)aniline | 395-65-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 偶氮苯
• 英文名称: N,N-dimethyl-4-((2-(trifluoromethyl)phenyl)diazenyl)aniline
• 英文别名: N,N-dimethyl-4-(2-trifluoromethyl-phenylazo)-aniline；N,N-Dimethyl-4-(2-trifluormethyl-phenylazo)-anilin；4-Dimethylamino-2'-trifluormethyl-azobenzol；4'-(Dimethylamino)-2-(trifluoromethyl)azobenzene；N,N-dimethyl-4-[[2-(trifluoromethyl)phenyl]diazenyl]aniline
• CAS: 395-65-3
• 化学式: C₁₅H₁₄F₃N₃
• 分子量: 293.291
• InChiKey: WNNLCEQWHGTTLP-UHFFFAOYSA-N

物化性质

• 沸点：
  390.8±42.0 °C(Predicted)
• 密度：
  1.17±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  21
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  28
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 sodium acetate 作用下， 生成 N,N-dimethyl-4-((2-(trifluoromethyl)phenyl)diazenyl)aniline
  参考文献：
  名称：

  Miller et al., Cancer Research, 1949, vol. 9, p. 652,653

  摘要：

  DOI：

文献信息

• Convenient and rapid diazotization and diazo coupling reaction via aryl diazonium nanomagnetic sulfate under solvent-free conditions at room temperature
  作者：Nadiya Koukabi、Somayeh Otokesh、Eskandar Kolvari、Ali Amoozadeh

  DOI：10.1016/j.dyepig.2015.03.041

  日期：2016.1

  acid is used for conversion of several types of aromatic amine, containing electron-withdrawing groups as well as electron-donating groups to the corresponding azo dyes in excellent yield. The synthesis of these compounds is described by the sequential diazotization–diazo coupling of various aromatic amines with sodium nitrite, nanomagnetic supported sulfonic acid and coupling agents under solvent-free

  纳米磁性负载的磺酸首次用于以优异的产率将包含吸电子基团和供电子基团的几种类型的芳族胺转化为相应的偶氮染料。在室温下无溶剂条件下，各种芳族胺与亚硝酸钠，纳米磁性负载的磺酸和偶联剂的顺序重氮化-重氮偶联，描述了这些化合物的合成。这种新方法具有许多优点，包括反应时间短，反应条件温和，避免了有害的酸和简单的后处理程序。更重要的是，负载在磁性纳米颗粒上的芳基重氮盐（芳基重氮纳米磁性硫酸盐）具有足够的稳定性，可以在室温下保持干燥状态。
• Liquid azo dyes
  作者：Siddanagouda Biradar、Ryohei Kasugai、Hisayoshi Kanoh、Hitoshi Nagao、Yasuhiro Kubota、Kazumasa Funabiki、Motoo Shiro、Masaki Matsui

  DOI：10.1016/j.dyepig.2015.10.024

  日期：2016.2

  Any liquid azo dyes, in which auxochrome such as dialkylamino, alkoxy, and amino group is attached in a molecule, were produced. In a series of 2-alkyl-4'-(dimethylamino)azobenzenes, the butyl, hexyl, octyl, and dodecyl derivatives were liquid at room temperature, whereas the propyl, 1-methylethyl, 1-methylpropyl, 1,1-dimethylethyl, and octadecyl derivatives were solid. Thus, it is essential for liquid azo dyes to have a medium n-alkyl group at the 2-position. In a series of 2-butyl-4'-(dialkylamino) azobenzenes, the dimethylamino, diethylamino, dibutylamino, dioctylamino, and didodecylamino derivatives were liquid. 2-Butyl-4'-methoxyazobenzene and 4-amino-3,5-dimethy1-2'-butylazobenenzne were also liquid, whereas 2-butyl-4'-hydroxyazobenznene, 4-amino-2'-butylazobenzene, and 2-butyl-4'-(methylamino)azobenzene were solid. The prevention of pi-pi stacking, alkyl alkyl interactions, and intermolecular hydrogen bond could produce liquid azo dyes. (c) 2015 Elsevier Ltd. All rights reserved.
• Jagupol'skii; Marenez, Zhurnal Obshchei Khimii, 1957, vol. 27, p. 1395,1396,1398;engl.Ausg.S.1477
  作者：Jagupol'skii、Marenez

  DOI：——

  日期：——
• Fukui et al., Nippon Kagaku Zasshi, 1958, vol. 79, p. 885,890
  作者：Fukui et al.

  DOI：——

  日期：——