2-Ethoxy-4-formylphenyl 2,4-dichlorobenzoate | 444110-64-9

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 缩酚酸和缩酚酸环醚类
• 英文名称: 2-Ethoxy-4-formylphenyl 2,4-dichlorobenzoate
• 英文别名: (2-ethoxy-4-formylphenyl) 2,4-dichlorobenzoate
• CAS: 444110-64-9
• 化学式: C₁₆H₁₂Cl₂O₄
• mdl: MFCD03422508
• 分子量: 339.175
• InChiKey: YSIHJPBCURKXBS-UHFFFAOYSA-N

物化性质

• 熔点：
  117-118 °C(Solv: benzene (71-43-2); hexane (110-54-3))
• 沸点：
  520.4±50.0 °C(Predicted)
• 密度：
  1.362±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  22
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2-Ethoxy-4-formylphenyl 2,4-dichlorobenzoate 、 苯胺 以 甲醇 为溶剂， 反应 0.25h， 以93%的产率得到(E)-2-ethoxy-4-((phenylimino)methyl)phenyl 2,4-dichlorobenzoate
  参考文献：
  名称：

  Synthesis of 3-alkoxy-4-acyloxyphenylmethylene(phenyl)amines

  摘要：

  Previously unknown E isomers of azomethines (Schiff bases) were synthesized from the vanillin and vanillal esters by the reaction with aniline.

  DOI：

  10.1134/s107036320804018x
• 作为产物：
  描述：

  2,4-二氯苯甲酸 在 吡啶 、 氯化亚砜 作用下， 以 苯 为溶剂， 生成 2-Ethoxy-4-formylphenyl 2,4-dichlorobenzoate
  参考文献：
  名称：

  New esters of vanillin and vanillal with some alkane-and arenecarboxylic acids

  摘要：

  Previously unknown esters were synthesized by the reaction of vanillin and vanillal with carboxylic acid chlorides.

  DOI：

  10.1134/s1070427206060322

文献信息

• Synthesis, film-forming properties, and thermal and light sensitivity of N,N′-bis[4-hydroxy(alkoxy, acyloxy)-3-alkoxyphenylmethylidene]benzene-1,4-diamines
  作者：E. A. Dikusar、N. G. Kozlov、V. I. Potkin、V. A. Azarko、A. P. Yuvchenko

  DOI：10.1134/s1070363208020175

  日期：2008.2

  Previously unknown E,E-isomeric Schiff bases were synthesized by reaction of p-phenylenediamine with 4-hydroxy-3-methoxybenzaldehyde, 3-ethoxy-4-hydroxybenzaldehyde, and their O-alkyl and O-acyl derivatives in anhydrous methanol. Film-forming properties and thermal and light sensitivity of the products were studied.

  之前未知的E,E-异构Schiff碱是通过在无水甲醇中将对苯二胺与4-羟基-3-甲氧基苯甲醛、3-乙氧基-4-羟基苯甲醛及其O-烷基和O-酰基衍生物反应合成的。对产物的成膜性能以及热稳定性和光敏感性进行了研究。
• Synthesis of 2-R-1,3-dioxanes, derivatives of functionally substituted aldehydes of vanillin series
  作者：E. A. Dikusar、V. I. Potkin、T. D. Zvereva、N. A. Zhukovskaya、S. K. Petkevich、A. S. Pavlyuchenkova、M. Yu. Murashova、A. P. Polikarpov、A. A. Shunkevich、A. P. Yuvchenko、R. M. Zolotar’

  DOI：10.1134/s1070428013020085

  日期：2013.2

  By the condensation of substituted aldehydes of vanillin series with 1,3-propanediol in boiling benzene in the presence of sulfo cation exchanger FIBAN K-1 as catalyst functionally 2-R-substituted 1,3-dioxanes were synthesized.
• 2-[3-Alkoxy-4-(hydroxy, alkoxy, acyloxy)phenyl]-2,3-dihydro-1H-benzimidazoles on the basis of vanillin and vanillal derivatives
  作者：E. A. Dikusar、N. G. Kozlov、V. I. Potkin

  DOI：10.1134/s1070363207110138

  日期：2007.11

  Previously unknown 2-[3-alkoxy-4-(hydroxy, alkoxy, acyloxy)phenyl]-2,3-dihydro-1H-benzimidazoles were prepared by the reaction of aldehydes of the vanillin series and their ethers and esters with 1,2-phenylenediamine in absolute methanol.
• Synthesis of functionally substituted 2,2′-arylmethylenebis(3-hydroxy-5,5-dimethylcyclohex-2-enones)
  作者：E. A. Dikusar、V. I. Potkin、S. K. Petkevich、R. M. Zolotar’、O. P. Chepik

  DOI：10.1134/s1070363214070068

  日期：2014.7
• Synthesis, film-forming properties, and photosensitivity of 4-alkoxy(acyloxy)-3-alkoxyphenylmethylene-(biphenyl-4-yl)amines
  作者：E. A. Dikusar、N. G. Kozlov、V. I. Potkin、V. A. Azarko、A. P. Yuvchenko

  DOI：10.1134/s1070363207100167

  日期：2007.10

  The reactions of ethers and esters of the vanillin series with biphenyl-4-ylamine in absolute methanol yielded previously unknown E isomers of biphenyl-substituted azomethines (Schiff bases). The film properties and photosensitivity of the new compounds were examined.