copper chromate | 13548-42-0

• 分子结构分类: 无机化合物 - 混合金属/非金属化合物 - 过渡金属氧阴离子化合物
• 英文名称: copper chromate
• 英文别名: copper(II) chromate；cupric chromate；copper;dioxido(dioxo)chromium
• CAS: 13548-42-0
• 化学式: CrO₄*Cu
• 分子量: 179.54
• InChiKey: PWGQHOJABIQOOS-UHFFFAOYSA-N

物化性质

• 熔点：
  decomposes at 400℃ [KIR78]
• 溶解度：
  不溶于水；溶于乙醇
• 稳定性/保质期：
  二水合物CuCrO₄·2H₂O为红褐色或黑色结晶，加热至325℃即放出氧气而分解。进一步加热至400℃可转化为四氧化铜铬Cr₂CuO₄，在650℃时则转变为二氧化亚铜铬CrCuO₂。该物质既溶于冷水又溶于酸，在酸性溶液中生成重铬酸铜。但在热水中，则会发生水解变成铬酸铜合氧化铜CuCrO₄·2CuO。在使用二价铜盐和铬酸盐进行反应时，不会得到预期的铬酸铜，而是生成铬酸氧化铜。

计算性质

• 辛醇/水分配系数(LogP)：
  -2.62
• 重原子数：
  6
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  80.3
• 氢给体数：
  0
• 氢受体数：
  4

ADMET

毒理性

• 副作用

职业性肝毒素 - 第二性肝毒素：职业环境中毒性效应的潜在性是基于人类摄入或动物实验的中毒案例。 肾毒素 - 该化学物质在职业环境中可能对肾脏有毒。 皮肤毒素 - 皮肤烧伤。 皮肤致敏剂 - 可以诱导皮肤过敏反应的制剂。 哮喘 - 由吸入刺激性或致敏性物质引发的 可逆性支气管收缩（支气管狭窄）。 IARC致癌物 - 1类：国际癌症研究机构将化学物质分类为确定的人类致癌物。 NTP致癌物 - 已知是人类致癌物。 ACGIH致癌物 - 确认的人类致癌物。

Occupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation. Nephrotoxin - The chemical is potentially toxic to the kidneys in the occupational setting. Dermatotoxin - Skin burns. Skin Sensitizer - An agent that can induce an allergic reaction in the skin. Asthma - Reversible bronchoconstriction (narrowing of bronchioles) initiated by the inhalation of irritating or allergenic agents. IARC Carcinogen - Class 1: International Agency for Research on Cancer classifies chemicals as established human carcinogens. NTP Carcinogen - Known to be a human carcinogen. ACGIH Carcinogen - Confirmed Human.

来源:Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

SDS

Name:	Copper(II) chromate Material Safety Data Sheet
Synonym:	None
CAS:	13548-42-0

Section 1 - Chemical Product MSDS Name:Copper(II) chromate Material Safety Data Sheet
Synonym:None

---

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
13548-42-0	Copper chromate	100	236-922-7

Hazard Symbols: T N
Risk Phrases: 36/37/38 43 46 49 50/53

---

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin. May cause sensitization by skin contact. May cause heritable genetic damage.
May cause cancer by inhalation. Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.Dangerous for the environment.
Potential Health Effects
Eye:
Causes eye irritation. May cause chemical conjunctivitis.
Skin:
Causes skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and diarrhea.
Inhalation:
Causes respiratory tract irritation. Can produce delayed pulmonary edema.
Chronic:
May cause cancer in humans. Effects may be delayed. Chronic exposure to water insoluble hexavalent chromium compounds has been shown to be associated with lung cancer and gastrointestinal tract tumors.
Repeated or prolonged exposure may cause allergic reactions in sensitive individuals.

---

Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth resuscitation.
Notes to Physician:
Treat symptomatically and supportively.

---

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or appropriate foam.

---

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.

---

Section 7 - HANDLING and STORAGE
Handling:
Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Wash clothing before reuse.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

---

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 13548-42-0: United Kingdom, WEL - TWA: (listed as chromium (vi) compounds): 0 mg/m3 TWA (as Cr) United Kingdom, WEL - STEL: (listed as chromium (vi) compounds): mg/m3 STEL (as Cr) Belgium - TWA: (listed as chromium (vi) compounds (certain water insoluble forms)): 0.01 mg/m3 VLE (as Cr) France - VME: (listed as chromium (vi) compounds): 0.05 mg/m3 VME Cr) Germany: (listed as chromium (vi) compounds): 0.05 mg/m3 VME (as Japan: (listed as chromium (vi) compounds): 0.05 mg/m3 OEL (as Cr 0.01 mg/m3 OEL (certain compounds, as Cr) Spain: (listed as chromium (vi) compounds (certain water insolubl forms)): 0.01 mg/m3 VLA-ED (as Cr) Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

---

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Crystalline powder
Color: brown
Odor: none reported
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: Not applicable.
Molecular Weight:

---

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid:
Incompatible materials, dust generation, excess heat.
Incompatibilities with Other Materials:
Not available.
Hazardous Decomposition Products:
Irritating and toxic fumes and gases, copper fumes, chromium fumes.
Hazardous Polymerization: Has not been reported

---

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 13548-42-0 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
Copper chromate - California: carcinogen, initial date 2/27/87 (listed as Chromium (VI) NTP: Known carcinogen (listed as Chromium (VI) compounds).
IARC: Group 1 carcinogen (listed as Chromium (VI) compounds).

---

Section 12 - ECOLOGICAL INFORMATION

---

Section 13 - DISPOSAL CONSIDERATIONS
Products which are considered hazardous for supply are classified as Special Waste and the disposal of such chemicals is covered by regulations which may vary according to location. Contact a specialist disposal company or the local waste regulator for advice. Empty containers must be decontaminated before returning for recycling.

---

Section 14 - TRANSPORT INFORMATION

IATA
Shipping Name: TOXIC SOLID, INORGANIC, N.O.S.
Hazard Class: 6.1
UN Number: 3288
Packing Group: II
IMO
Shipping Name: TOXIC SOLID, INORGANIC, N.O.S.
Hazard Class: 6.1
UN Number: 3288
Packing Group: II
RID/ADR
Shipping Name: Toxic solid, inorganic, n.o.s.
Hazard Class: 6.1,65b
UN Number: 3288
Packing group: II

---

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T N
Risk Phrases:
R 46 May cause heritable genetic damage.
R 49 May cause cancer by inhalation.
R 36/37/38 Irritating to eyes, respiratory system
and skin.
R 43 May cause sensitization by skin contact.
R 50/53 Very toxic to aquatic organisms, may cause
long-term adverse effects in the aquatic environment.
Safety Phrases:
S 53 Avoid exposure - obtain special instructions
before use.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
S 60 This material and its container must be
disposed of as hazardous waste.
S 61 Avoid release to the environment. Refer to
special instructions/safety data sheets.
WGK (Water Danger/Protection)
CAS# 13548-42-0: No information available.
Canada
CAS# 13548-42-0 is listed on Canada's NDSL List.
CAS# 13548-42-0 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 13548-42-0 is listed on the TSCA inventory.

---

SECTION 16 - ADDITIONAL INFORMATION
N/A

制备方法与用途

生产方法

制法 取4.5g铬酸钠溶于20mL水中制成溶液，将该溶液在冷却下加入到用17g碳酸铜（CuCO₃）溶于含有30g三氧化 chromium（CrO₃）的30mL水而成的溶液中。滤出生成的红褐色沉淀，用冷水洗涤。所得的二水合物即使置于干燥器中减压，其结晶水也不容易失去。

类别

有毒物质

爆炸物危险特性

与硫化物反应自燃爆炸

可燃性危险特性

不可燃烧；火场产生有毒含铬、铜化物烟雾

储运特性

库房低温、通风、干燥；防火；防高温

灭火剂

水、二氧化碳、干粉、泡沫

反应信息

• 作为反应物：
  描述：

  copper chromate 在 air 作用下， 以 neat (no solvent) 为溶剂， 生成 copper(II) chromite
  参考文献：
  名称：

  Gibbs energy of formation of CuCrO4 and phase relations in the system Cu-Cr-O below 735 K

  摘要：

  A solid state galvanic cell incorporating yttria-stabilized zirconia electrolyte and ruthenium(IV) oxide electrodes has been used to measure the equilibrium chemical potential of oxygen corresponding to the decomposition of CuCrO4 in the range 590-760 K. For the reaction CuO(tenorite)+CuCr2O4(spinel)+1.50,(g)-->2CuCrO4(orth), DELTAG(THETA) = -183 540 + 249.6T(+/-900) J mol-1. The decomposition temperature of CuCrO4 in pure oxygen at a pressure of 1.01 x 10(5) Pa is 735(+/-1) K. By combining the results obtained in this study with data on the Gibbs energy of formation of CuCr2O4 and CuCrO2 reported earlier, the standard Gibbs energy of formation of CuCrO4 and the phase relations in the system Cu-Cr-O at temperatures below 735 K have been deduced. Electron microscopic studies have indicated that the decomposition of CuCrO4 to CuCr2O4 is topotactic.

  DOI：

  10.1016/0040-6031(92)80176-w
• 作为产物：
  描述：

  chromium(III) oxide * x H2O 在 copper(II) hydroxide 、 氧气 作用下， 生成 copper chromate
  参考文献：
  名称：

  Gmelin Handbuch der Anorganischen Chemie, Gmelin Handbook: Cr: MVol.B, 27, page 52 - 54

  摘要：

  DOI：
• 作为试剂：
  描述：

  1,4,4ar,5,8,8at,9ac,10at-Octahydro-anthrachinon 在 copper chromate 、 三氯苯 作用下， 生成 蒽醌
  参考文献：
  名称：

  DE554878

  摘要：

  公开号：

文献信息

• Method of making a semiconductor with copper passivating film
  申请人：Lucent Technologies Inc.

  公开号：US06114234A1

  公开（公告）日：2000-09-05

  A method of making a semiconductor with a passivating film for copper interconnects includes the step of etching a first set of trench openings within a second oxide layer and then through an etch stop layer that has been deposited over a first oxide layer on a semiconductor substrate. At least a second set of openings are etched in the first oxide layer within the bounds defined by each of a first set of openings. A copper layer is deposited and a passivating film formed on top of the deposited copper layer by depositing one of either a chromate or chromite on the deposited copper layer and forming a respective copper chromate or copper chromite composition. The passivating film is chemically mechanically polished with a slurry containing a respective nitric acid when the passivating film is formed from a chromite and ammonium hydroxide when the passivating film is formed from a chromate.

  制造具有铜互连通道的半导体的一种方法包括以下步骤：在半导体衬底上沉积第一氧化物层，然后在其上沉积刻蚀停止层；在第二氧化物层上刻蚀第一组沟槽开口，然后通过刻蚀停止层和第一氧化物层，在每个第一组开口所定义的边界内刻蚀至少第二组开口；在刻蚀后的表面上沉积铜层，然后在其上形成一种保护膜，其中，通过在沉积的铜层上沉积铬酸盐或铬酸盐之一，并形成相应的铜铬酸盐或铜铬酸盐组成，来形成保护膜；当保护膜是从铬酸盐形成时，使用含有硝酸的研磨液进行化学机械抛光，当保护膜是从铬酸盐形成时，使用氨水进行化学机械抛光。
• High-resolution electron microscopy of copper chromate and the products of its thermal decomposition
  作者：Olaf Marks、John R. Günter

  DOI：10.1016/0022-4596(88)90084-9

  日期：1988.11

  Copper chromate and its thermal decomposition products have been investigated by thermogravimetry, X-ray powder and single-crystal diffraction, and high-resolution electrom microscopy in order to study the micromorphology of the intermediate two-phase product, consisting of CuCr2O4 and CuO, known as Adkins catalyst, and the mechanism of its formation. Both steps of the thermal decomposition of CuCrO4

  为了研究由CuCr 2 O 4和CuCr 2 O组成的中间两相产物的微观形貌，已通过热重分析，X射线粉末和单晶衍射以及高分辨率电镜对铬酸铜及其热分解产物进行了研究。CuO，称为Adkins催化剂，及其形成机理。CuCrO 4热分解为CuCr 2 O 4 + CuO和CuCrO 2的两个步骤都是完全可行的。CuO形成细小夹杂物（直径5-10 nm），它们紧密地嵌入孪生的CuCr 2 O 4基质中。
• Chromate Incarceration by Nanojars and Its Removal from Water by Liquid–Liquid Extraction
  作者：Wisam A. Al Isawi、Christian K. Hartman、Pooja Singh、Matthias Zeller、Gellert Mezei

  DOI：10.1021/acs.inorgchem.3c00262

  日期：——

  chemical stability studies toward NH3, methanol, and Ba2+ ions are employed to explore the binding of the CrO42– ion by nanojars. Titration of carbonate nanojars [CO3 ⊂ Cu(OH)(pz)}n]2– with H2CrO4 leads to anion exchange and the formation of chromate nanojars [CrO4 ⊂ Cu(OH)(pz)}n]2–. Details of chromate binding by H-bonding based on single-crystal structures of (Bu4N)2[CrO4 ⊂ Cu(OH)(pz)}28], four pseudopolymorphs

  展示了使用纳米罐作为萃取剂，将双负铬酸盐离子 (CrO 4 2– ) 从中性水溶液中前所未有地液-液萃取到脂肪烃溶剂中。将铬酸盐从水中转移到有机溶剂中极具挑战性，因为它具有巨大的水合能 (Δ G h ° = −950 kJ/mol) 和强氧化能力。由于其高度亲水性的阴离子结合口袋内衬有大量氢键供体 OH 基团，分子式为 [ cis -Cu II (μ-OH)(μ-4-Rpz)] n ( n = 27–33; pz = 吡唑酸阴离子；R = H 或正辛基）与 CrO 4强烈结合2–离子并有效地将其从水中转移到正庚烷或 C 11 – C 13异烷烃（当 R =正辛基时）。通过用酸性水溶液汽提，可以很容易地从有机层中回收萃取的铬酸盐。电喷雾电离质谱、紫外可见光和顺磁性1 H NMR 光谱、X 射线晶体学和溶液中的热稳定性研究以及对 NH 3、甲醇和 Ba 2+离子的化学稳定性研究用于探索 CrO
• Study of copper-chromium oxide catalyst
  作者：F. Hanic、I. Horváth、G. Plesch、Ľ. Gáliková

  DOI：10.1016/0022-4596(85)90318-4

  日期：1985.9

  The kinetics, mechanism, and activation energy of the isothermal decomposition of CuCrO4 was studied using an isothermal TG method and an X-ray high-temperature diffraction technique in either air or a flowing atmosphere of N2. The enthalpy change ΔH of the decomposition reaction

  使用等温TG方法和X射线高温衍射技术，在空气或N 2流动气氛中研究了CuCrO 4的等温分解的动力学，机理和活化能。分解反应的焓变ΔH
• TG–MS study on the kinetics and mechanism of thermal decomposition of copper ethylamine chromate, a new precursor for copper chromite catalyst
  作者：Sanoop Paulose、Deepthi Thomas、T. Jayalatha、R. Rajeev、Benny K. George

  DOI：10.1007/s10973-015-5207-7

  日期：2016.5

  that of copper ammonium chromate, a conventional precursor for copper chromite catalyst. TG–MS analysis for the decomposition of CEC revealed that the decomposition starts with the liberation of ethylamine. The change in enthalpy for the decomposition reaction of copper ethylamine chromate was higher than that of copper ammonium chromate due to the oxidation of ethyl group. The reducing atmosphere created

  亚铬酸铜是一种众所周知的燃烧速率改进剂，用于燃烧复合固体推进剂。本研究通过沉淀法合成了亚铬酸铜催化剂的新型前体碱性铜乙胺铬酸盐（CEC）。通过热重分析-质谱（TG-MS）和X射线衍射技术对前体进行热分解，并将其与铬酸铜铵（传统的亚铬酸铜催化剂的前驱体）进行比较。TG-MS分析CEC的分解表明，分解从乙胺的释放开始。由于乙基的氧化，铜乙胺铬酸铜的分解反应的焓变化高于铬酸铵铜。2 O 4，CuCrO 2和CuO，而铬酸铵铜的氧化气氛产生CuCr 2 O 4和CuO的混合物。基于Criado和Coats-Redfern方法的机理研究表明，CEC遵循随机成核（F1）机制，作为热分解过程的速率决定步骤。