2-Methoxy-2-methylpropane;methylsulfinylmethane

• 分子结构分类: 有机化合物 - 有机硫化合物 - 亚砜
• 英文名称: 2-Methoxy-2-methylpropane;methylsulfinylmethane
• 英文别名: 2-methoxy-2-methylpropane;methylsulfinylmethane
• 化学式: C7H18O2S
• 分子量: 166.28
• InChiKey: FGGCNQUUSGPGJT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.43
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  45.5
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• Salts, co-crystals, and polymorphs of an anxiolytic compound
  申请人：Bionomics Limited

  公开号：US10266529B2

  公开（公告）日：2019-04-23

  The present invention provides crystalline Forms FUM-P3, FUM-P4, MLA-P3 and MLA-P4 of compound formula 1 and related methods of treating and/or preventing a disease, such as a central nervous system disease (e.g., an anxiety disorder), using a crystalline Form FUM-P3, FUM-P4, MLA-P3 and MLA-P4 of compound formula 1 and/or pharmaceutical compositions thereof.

  本发明提供了化合物式1的结晶形式FUM-P3、FUM-P4、MLA-P3和MLA-P4，以及使用化合物式1的结晶形式FUM-P3、FUM-P4、MLA-P3和MLA-P4和/或其药物组合物治疗和/或预防疾病（如中枢神经系统疾病，如焦虑症）的相关方法。
• SALTS, CO-CRYSTALS, AND POLYMORPHS OF AN ANXIOLYTIC COMPOUND
  申请人：Bionomics Limited

  公开号：EP2970247A1

  公开（公告）日：2016-01-20
• US9745296B2
  申请人：——

  公开号：US9745296B2

  公开（公告）日：2017-08-29
• [EN] SALTS, CO-CRYSTALS, AND POLYMORPHS OF AN ANXIOLYTIC COMPOUND<br/>[FR] SELS, COCRISTAUX ET POLYMORPHES D'UN COMPOSÉ ANXIOLYTIQUE
  申请人：BIONOMICS LTD

  公开号：WO2014138812A1

  公开（公告）日：2014-09-18

  The present invention provides amorphous arid crystalline forms of 1-ethyl-6-(indan-2- ylamino)-3-(morpholine-4-carbonyl)-1,8-naphthyridin-4-one (compound 1), and salts, co- crystals, and pharmaceutical compositions thereof. The invention also provides methods of treating and/or preventing a disease, such as a central nervous system disease (e.g., an anxiety disorder), using the amorphous and crystelline forms, and salts, co-crystals, and pharmaceutical compositions thereof.