1-Pyrazolidin-1-ylpiperidine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: 1-Pyrazolidin-1-ylpiperidine
• 英文别名: 1-pyrazolidin-1-ylpiperidine
• 化学式: C₈H₁₇N₃
• 分子量: 155.24
• InChiKey: DNLZJDRJHXCTRP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  18.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Pharmaceutical combination of opioid and prostaglandin compound
  申请人：SUCAMPO AG

  公开号：US10561649B2

  公开（公告）日：2020-02-18

  Provided is a method for treating a condition or disease which is one of the indications for opioid use, which comprises administering a combination of: (a) a pharmaceutically effective amount of an opioid, and (b) a pharmaceutically effective amount of a prostaglandin (PG) compound represented by the formula (I): to a patient in need thereof.

  提供了一种治疗属于阿片类药物使用适应症之一的病症或疾病的方法，其中包括施用以下药物的组合： (a) 有效药用量的阿片类药物，和 (b) 药学上有效量的由式（I）代表的前列腺素（PG）化合物： 给有需要的病人。
• PHARMACEUTICAL COMBINATION OF OPIOID AND PROSTAGLANDIN COMPOUND
  申请人：SUCAMPO AG

  公开号：US20180311233A1

  公开（公告）日：2018-11-01

  Provided is a method for treating a condition or disease which is one of the indications for opioid use, which comprises administering a combination of: (a) a pharmaceutically effective amount of an opioid, and (b) a pharmaceutically effective amount of a prostaglandin (PG) compound represented by the formula (I): to a patient in need thereof.