N²-isopropyl-[1,3,5]triazine-2,4-diyldiamine | 69844-52-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 三嗪类
• 英文名称: N²-isopropyl-[1,3,5]triazine-2,4-diyldiamine
• 英文别名: N²-Isopropyl-[1,3,5]triazin-2,4-diyldiamin；2-Amino-6-(isopropylamino)1,3,5-triazine；2-N-propan-2-yl-1,3,5-triazine-2,4-diamine
• CAS: 69844-52-6
• 化学式: C₆H₁₁N₅
• 分子量: 153.187
• InChiKey: WBEKRMVYCWRRDJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  76.7
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  异丙胺 、 二聚氰胺 、 甲酸乙酯 生成 N²-isopropyl-[1,3,5]triazine-2,4-diyldiamine
  参考文献：
  名称：

  Guanamine Diuretics

  摘要：

  DOI：

  10.1021/ja01575a064

文献信息

• Novel substituted nitrodiphenyl ethers, herbicidal compositions containing them, processes for the preparation thereof and the use thereof for combating weeds
  申请人：ROHM AND HAAS COMPANY

  公开号：EP0020052A1

  公开（公告）日：1980-12-10

  Novel substituted nitrodiphenyl ethers, herbicidal compositions containing them, processes for the preparation thereof and the use thereof for combating weeds. Novel compounds are provided which exhibit activity as herbicides for combating weeds. The novel compounds have the formula: wherein X is hydrogen, halo, trihalomethyl, alkyl, cyano or nitro; X' is hydrogen, halo or trihalomethyl; X2 is trihalomethyl or halo; Y is 0, NH, NR1 or S; R1 and R2 are the same or different and are selected from hydrogen, (C1-C4) alkyl, phenyl and phenyl (C1-C4) alkyl; n is an integer of from 1 to 5; and Z is carboxy, amino, monoalkylamino, or dialkylamino. Also provided are agronomically acceptable salts, esters and amides of a compound of Formula I when Z is carboxy.

  新型取代的硝基二苯醚、含有它们的除草组合物、其制备工艺及其用于除草的用途。 本发明提供了具有除草活性的新型化合物。这些新型化合物的化学式如下 式中 X 是氢、卤素、三卤甲基、烷基、氰基或硝基； X' 是氢、卤素或三卤甲基； X2 是三卤甲基或卤素； Y 是 0、NH、NR1 或 S； R1 和 R2 相同或不同，选自氢、（C1-C4）烷基、苯基和苯基（C1-C4）烷基； n 是 1 至 5 的整数；以及 Z 是羧基、氨基、单烷基氨基或二烷基氨基。 当 Z 为羧基时，还提供农艺学上可接受的式 I 化合物的盐、酯和酰胺。
• METHODS AND COMPOSITIONS FOR STIMULATION OF CHIMERIC ANTIGEN RECEPTOR T CELLS WITH HAPTEN LABELLED CELLS
  申请人：Seattle Children's Hospital (dba Seattle Children's Research Institute)

  公开号：US20210317407A1

  公开（公告）日：2021-10-14

  Some embodiments of the methods and compositions provided herein relate to the use of hapten labeled cells to stimulate chimeric antigen receptor (CAR) T cells. In some embodiments, CAR T cells can include a CAR that specifically binds to a hapten. Some embodiments relate to the in vivo or in vitro stimulation CAR T cells by hapten labeled cells.