sodium;3,7-dimethyloctan-3-olate

• 分子结构分类: 有机化合物 - 有机盐 - 有机金属盐
• 英文名称: sodium;3,7-dimethyloctan-3-olate
• 化学式: C10H21NaO
• mdl: MFCD02684288
• 分子量: 180.26
• InChiKey: TUAUHXBPTQXSPL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  12
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  23.1
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• Process for the preparation of an indole derivative
  申请人：F. Hoffmann-La Roche AG

  公开号：EP2011783A1

  公开（公告）日：2009-01-07

  A process for the preparation of indole derivatives of formula (I): which are useful as intermediates in the preparation of i.a. pharmaceutically active compounds.

  一种制备式(I)吲哚衍生物的方法：这些衍生物在制备具有药用活性的化合物中起中间体作用。
• [EN] PROCESS FOR THE PREPARATION OF SULFAMIDE DERIVATIVES<br/>[FR] PROCÉDÉ DE PRÉPARATION DE DÉRIVÉS DE SULFAMIDES
  申请人：JANSSEN PHARMACEUTICA NV

  公开号：WO2013049021A1

  公开（公告）日：2013-04-04

  The present invention is directed to a process for the preparation of sulfamide derivatives.

  本发明涉及一种制备磺胺酰胺衍生物的方法。
• Methods of synthesizing 3-amino-1,2-4-benzotriazines
  申请人：Moskalev V. Nikolai

  公开号：US20060142569A1

  公开（公告）日：2006-06-29

  An improved method of producing 3-amino-1,2,4-benzotriazines using nitrobenzene or a derivative thereof, a guanidine salt and a base as reactants is provided. The method is carried out at a moderate reaction temperature without producing halide wastes derived from nucleophilic substitution and acid byproducts.

  提供了一种改进的方法，用硝基苯或其衍生物、胍盐和碱作为反应物来生产3-氨基-1,2,4-苯并三嗪。该方法在适度的反应温度下进行，不会产生来自亲核取代和酸副产物的卤化物废物。
• [EN] CATALYTIC PROCESS FOR PREPARING AN α,β-ETHYLENICALLY UNSATURATED CARBOXYLIC ACID SALT<br/>[FR] PROCÉDÉ CATALYTIQUE POUR LA PRÉPARATION D'UN SEL D'ACIDE CARBOXYLIQUE À INSATURATION ÉTHYLÉNIQUE α ET β
  申请人：BASF SE

  公开号：WO2021185879A1

  公开（公告）日：2021-09-23

  A catalytic process for preparing an α,β-ethylenically unsaturated carboxylic acid salt, comprising a) contacting an alkene and carbon dioxide with a carboxylation catalyst, an organic solvent, and an alkoxide having a secondary or tertiary carbon atom directly bound to an [O-] group, to obtain a crude reaction product comprising the α,β-ethylenically unsaturated carboxylic acid salt and an alcohol by-product which is the conjugate acid of the alkoxide, b) allowing the α,β-ethylenically unsaturated carboxylic acid salt to precipitate out from the crude reaction product; and c) subjecting at least part of the crude reaction product to a mechanical separation step while maintaining the alcohol by-product in liquid form to obtain a solid phase comprising the α,β-ethylenically unsaturated carboxylic acid salt and a liquid phase comprising the carboxylation catalyst, the organic solvent and the alcohol by-product. The process allows for easy separation of the α,β-ethylenically unsaturated carboxylic acid salt by a mechanical separation operation.

  一种制备α，β-乙烯基不饱和羧酸盐的催化过程，包括a）将烯烃和二氧化碳与羧化催化剂、有机溶剂和直接与[O-]基团相结合的二级或三级碳原子的烷氧基接触，以获得包含α，β-乙烯基不饱和羧酸盐和醇副产物的原始反应产物，该醇副产物是烷氧基的共轭酸，b）使α，β-乙烯基不饱和羧酸盐从原始反应产物中沉淀出来；c）在保持醇副产物处于液态的情况下，对至少部分原始反应产物进行机械分离步骤，以获得包含α，β-乙烯基不饱和羧酸盐的固相和包含羧化催化剂、有机溶剂和醇副产物的液相。该过程允许通过机械分离操作轻松分离α，β-乙烯基不饱和羧酸盐。
• PROCESS FOR THE PREPARATION OF INDOLE DERIVATIVES
  申请人：Bachmann Stephan

  公开号：US20090012311A1

  公开（公告）日：2009-01-08

  A process for the preparation of indole derivatives of formula (I): which are useful as intermediates in the preparation of pharmaceutically active compounds.

  一种制备式(I)的吲哚衍生物的方法，该衍生物在制备药物活性化合物的中间体中有用。