S-n-hexyl cyclohexyldithiocarbamate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 二硫代氨基甲酸及其衍生物
• 英文名称: S-n-hexyl cyclohexyldithiocarbamate
• 英文别名: n-Hexyl cyclohexyldithiocarbamate；hexyl N-cyclohexylcarbamodithioate
• 化学式: C₁₃H₂₅NS₂
• 分子量: 259.48
• InChiKey: AECBXULHQXXMTQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  16
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  69.4
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  二硫化碳 、 1-氯己烷 、 环己胺 在 苄基三甲基氢氧化铵 作用下， 以 二甲基亚砜 为溶剂， 反应 4.33h， 以88%的产率得到S-n-hexyl cyclohexyldithiocarbamate
  参考文献：
  名称：

  Triton-B Catalyzed Efficient One-Pot Synthesis of Dithiocarbamate Esters

  摘要：

  A novel process for the one-step chemoselective conversion of alkyl halides into dithiocarbamates as protected amines was developed using benzyltrimethylammonium hydroxide (Triton-B) in presence of carbon disulfide. Thus, dithiocarbamates of different amines were prepared in very good to excellent yields. This protocol is mild, chemoselective, and efficient compared to other methods.

  DOI：

  10.1007/s00706-006-0438-8

文献信息

• A High Yielding, One-Pot, Triton-B Catalyzed Synthesis of Dithiocarbamates Using Alcoholic Tosylates
  作者：Devdutt Chaturvedi、Suprabhat Ray

  DOI：10.1007/s00706-005-0460-2

  日期：2006.4

  A novel process for the one-step chemoselective conversion of alcoholic tosylates into. dithiocarbamates as protected amines was developed using benzyltlimethylammoniumhydroxide (Triton-B) in presence of carbon disulfide. Thus, dithiocarbamates of different amines were prepared in very good to excellent yields. This protocol is mild, chemoselective, and efficient compared to other reported methods.
• Triton-B Catalyzed Efficient One-Pot Synthesis of Dithiocarbamate Esters
  作者：Devdutt Chaturvedi、Suprabhat Ray

  DOI：10.1007/s00706-006-0438-8

  日期：2006.3

  A novel process for the one-step chemoselective conversion of alkyl halides into dithiocarbamates as protected amines was developed using benzyltrimethylammonium hydroxide (Triton-B) in presence of carbon disulfide. Thus, dithiocarbamates of different amines were prepared in very good to excellent yields. This protocol is mild, chemoselective, and efficient compared to other methods.