1-(Piperidin-1-yl)-2-((5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl)thio)ethanone

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: 1-(Piperidin-1-yl)-2-((5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl)thio)ethanone
• 英文别名: 1-piperidin-1-yl-2-[(5-pyridin-4-yl-1,3,4-oxadiazol-2-yl)sulfanyl]ethanone
• 化学式: C₁₄H₁₆N₄O₂S
• mdl: MFCD04274301
• 分子量: 304.37
• InChiKey: IRZKMQLVMDFNTD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  97.4
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  2-[(5-pyridin-4-yl-1,3,4-oxadiazol-2-yl)sulfanyl]acetyl chloride 、 哌啶 以45%的产率得到
  参考文献：
  名称：

  SALAMA, M. A.;MOTI, F. M. A.;GHATTAS, A. A. G.;ABDULLAH, A., EGYPT. J. CHEM., 1981, 24, N 1-3, 47-51

  摘要：

  DOI：

文献信息

• Antiviral Compounds and Uses Thereof
  申请人：Shaw Megan

  公开号：US20130137678A1

  公开（公告）日：2013-05-30

  Described herein are Compounds, compositions comprising such Compounds, and the use of such Compounds and compositions as anti-viral agents. In one aspect, provided herein are methods of inhibiting viral replication using Compounds described herein or compositions thereof. In another aspect, provided herein are methods for preventing a symptom of a viral infection using a Compound, or a composition thereof. In another aspect, provided herein are methods of treating and/or managing viral infection using a compound or a composition thereof.
• US9096585B2
  申请人：——

  公开号：US9096585B2

  公开（公告）日：2015-08-04
• [EN] ANTIVIRAL COMPOUNDS AND USES THEREOF<br/>[FR] COMPOSÉS ANTIVIRAUX ET LEURS UTILISATIONS
  申请人：SINAI SCHOOL MEDICINE

  公开号：WO2011150413A1

  公开（公告）日：2011-12-01

  Described herein are Compounds, compositions comprising such Compounds, and the use of such Compounds and compositions as anti-viral agents. In one aspect, provided herein are methods of inhibiting viral replication using Compounds described herein or compositions thereof. In another aspect, provided herein are methods for preventing a symptom of a viral infection using a Compound, or a composition thereof. In another aspect, provided herein are methods of treating and/or managing viral infection using a compound or a composition thereof.