(E)-(((5-nitrothien-2-yl)methylene)(4-pyridyl)methyl)diethylamine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 噻吩类
• 英文名称: (E)-(((5-nitrothien-2-yl)methylene)(4-pyridyl)methyl)diethylamine
• 英文别名: (E)-N,N-diethyl-2-(5-nitrothiophen-2-yl)-1-pyridin-4-ylethenamine
• 化学式: C₁₅H₁₇N₃O₂S
• 分子量: 303.385
• InChiKey: BIRQSRLMVZZQGF-SDNWHVSQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  21
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  90.2
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  4-乙炔基吡啶 在 bis-triphenylphosphine-palladium(II) chloride 、 copper(l) iodide 、 二异丙胺 作用下， 反应 37.0h， 生成 (E)-(((5-nitrothien-2-yl)methylene)(4-pyridyl)methyl)diethylamine
  参考文献：
  名称：

  Preparation of push-pull type chromophores via nitrothiophene induced Michael type reaction of alkynes

  摘要：

  Nitrothiophene activates a neighboring alkyne to undergo Michael addition with dialkylamines and methanol to afford push-pull type chromophores. These compounds exhibit a large positive solvatochromism. The olefinic moiety in (Z)-(((5-nitrothien-2-yl)methylene(ferrocenyl)methyl)diethylamine (14) can be converted to an alpha-diketone. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4020(99)00871-6

文献信息

• Preparation of push-pull type chromophores via nitrothiophene induced Michael type reaction of alkynes
  作者：Iuan-Yuan Wu、Jiann T. Lin、Chyi-Shiun Li、Wen Chao Wang、Tai Hsiang Huang、Yuh S. Wen、Tahsin Chow、Chiitang Tsai

  DOI：10.1016/s0040-4020(99)00871-6

  日期：1999.12

  Nitrothiophene activates a neighboring alkyne to undergo Michael addition with dialkylamines and methanol to afford push-pull type chromophores. These compounds exhibit a large positive solvatochromism. The olefinic moiety in (Z)-(((5-nitrothien-2-yl)methylene(ferrocenyl)methyl)diethylamine (14) can be converted to an alpha-diketone. (C) 1999 Elsevier Science Ltd. All rights reserved.