cis-Merocyanine 540 | 62796-23-0

• 物质功能分类: 生物化工 - 生化试剂 - 荧光成像
• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并恶唑啉
• 英文名称: cis-Merocyanine 540
• 英文别名: merocyanine 540；sodium;3-[(2Z)-2-[(Z)-4-(1,3-dibutyl-4,6-dioxo-2-sulfanylidene-1,3-diazinan-5-ylidene)but-2-enylidene]-1,3-benzoxazol-3-yl]propane-1-sulfonate
• CAS: 62796-23-0
• 化学式: C₂₆H₃₂N₃O₆S₂*Na
• 分子量: 569.678
• InChiKey: OSQUFVVXNRMSHL-UFZWEZEMSA-M

物化性质

• 熔点：
  285 °C (dec.)(lit.)
• 溶解度：
  可溶于DMSO

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  38
• 可旋转键数：
  12
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  151
• 氢给体数：
  0
• 氢受体数：
  8

安全信息

• 危险品标志：
  Xi
• 安全说明：
  S26,S36
• 危险类别码：
  R36/37/38
• WGK Germany：
  3
• RTECS号：
  DM4866500
• 危险标志：
  GHS07
• 危险性描述：
  H315,H319,H335
• 危险性防范说明：
  P261,P305 + P351 + P338

反应信息

• 作为产物：
  描述：

  merocyanine 540 以 甲醇 为溶剂， 生成 cis-Merocyanine 540
  参考文献：
  名称：

  顺式-反式异构化反应的动态溶剂化作用：花青素540在极性溶剂中的光异构化

  摘要：

  The fluorescence quantum yield, PHI(f), of merocyanine 540 in n-alkyl alcohol and n-alkanenitrile solvents was measured as a function of temperature and solvent shear viscosity at ambient pressure. The Strickler-Berg equation was used to calculate the radiative rate, k(r), from the absorption and fluorescence spectra. The values of PHI(f)and k(r) were used to obtain the rate of photoisomerization, k(iso). This rate is consistent with the Smoluchowski limit of the Kramers theory for activated barrier crossing. The intrinsic barrier height, which is taken to be equal to the difference between the single-solvent activation energy and the viscosity activation energy, is lower in alcohols than in nitriles. The lower barrier can be partly rationalized in terms of static solvation effects which stabilize the twisted state of the dye. Because of the dye's zwitterionic resonance structures, hydrogen bonding plays a key role in stabilizing the twisted state in alcohols. The intrinsic barrier depends weakly on the solvent for the nitriles, but it decreases dramatically in going from lower to higher alcohols. The behavior of the intrinsic barrier in these solvents is attributed to dynamical solvation effects which couple the solvent polarization to the intramolecular motion.

  DOI：

  10.1021/j100112a040

文献信息

• Chemically-resistant sensor devices, and systems and methods for using same
  申请人：——

  公开号：US20020173040A1

  公开（公告）日：2002-11-21

  A sensor device is disclosed, as well as methods and systems for determining a barrier property of each coating of an array of barrier coatings deposited onto a fluid-permeable or fluid-impermeable substrate. The systems and methods include the sensor device having a sensing layer responsive to a fluid of interest for which the barrier property of the array of coatings are desired to be determined. The sensor device further includes an overlayer disposed between the array of barrier coatings and the sensing layer. The overlayer protects the sensing layer from being damaged by the coatings.

  本发明公开了一种传感器装置，以及用于确定沉积在可渗透流体或不可渗透流体基底上的阻隔涂层阵列中每个涂层的阻隔特性的方法和系统。这些系统和方法包括传感器装置，该装置具有一个传感层，该传感层可对所需确定涂层阵列阻隔性能的流体做出响应。传感器装置还包括设置在阻隔涂层阵列和传感层之间的覆盖层。覆盖层可保护传感层不受涂层的损坏。
• Sensor arrays for detecting analytes in fluids
  申请人：Illumina, Inc.

  公开号：US20030198573A1

  公开（公告）日：2003-10-23

  In accordance with the objects outlined above, the present invention provides sensor arrays for the detection of target analytes. The sensor arrays comprising a substrate comprising a surface comprising discrete sites, each discrete site comprising a solvatochromic dye and at least one micro-environment moiety (MEM), both of which are preferably covalent attached to the discrete site. In some aspects, the discrete sites comprise microspheres to which the dyes and MEMs are attached, again, preferably covalently. The dye(s) and MEM(s) at each site can be independently attached, or they can be co-attached using a linker.

  根据上述目的，本发明提供了用于检测目标分析物的传感器阵列。传感器阵列包括一个基底，基底的表面包括离散位点，每个离散位点包括溶解变色染料和至少一个微环境分子（MEM），两者最好共价连接到离散位点上。在某些方面，离散位点包括微球，染料和微环境分子也以共价方式附着在微球上。每个位点上的染料和 MEM 可以独立连接，也可以使用连接剂共同连接。
• Device arrays and methods for operation in aggressive solvents and for measurements of barrier properties of plurality of coatings
  申请人：General Electric Company

  公开号：US20040150827A1

  公开（公告）日：2004-08-05

  Methods and devices are disclosed for measuring barrier properties of a barrier coating or coating arrays where each barrier coating has a small cross section. To reduce the edge effects in the measurements of barrier properties, measurements are made using a substrate which can be flat, cylindrical or spherical structure coated with a chemically sensitive layer, a solvent resistant layer and an array of barrier coatings. The coated substrate which can be flat, cylindrical or spherical is exposed to a material of interest that has the ability to produce an analyzable variation in the chemically sensitive layer, thereby providing the ability to detect an impact of the material of interest on the barrier coatings. In one variation, an optical radiation interacts with the substrate structure, a resulting initial optical radiation associated with the initial optical radiation and each barrier coating is detected, and any impacts on the coatings by the material of interest are correlated to a value of a barrier property for each of the array of barrier coatings.

  本发明公开了用于测量阻隔涂层或涂层阵列的阻隔性能的方法和装置，其中每个阻隔涂层的横截面都很小。为减少阻隔性能测量中的边缘效应，使用涂有化学敏感层、耐溶剂层和阻隔涂层阵列的基底进行测量，基底可以是平面、圆柱形或球形结构。涂有涂层的基底可以是平面、圆柱形或球形，将其暴露在相关材料中，该材料能够在化学敏感层中产生可分析的变化，从而提供检测相关材料对阻隔涂层的影响的能力。在一种变化中，光辐射与基底结构相互作用，检测与初始光辐射和每个阻隔涂层相关的初始光辐射，并将相关材料对涂层的任何影响与每个阻隔涂层阵列的阻隔特性值相关联。
• INTRINSICALLY COLORED, LUMINESCENT SILK FIBROIN AND A METHOD OF PRODUCING THE SAME
  申请人：Tansil Natalia Chendrawati

  公开号：US20120039813A1

  公开（公告）日：2012-02-16

  This present invention proposes a method of producing intrinsically colored, luminescent silk fibroin by feeding silkworms with feed comprising the luminescent dyes as well as the appropriate degumming process to remove sericin while retaining the dyes in silk fibroin are also described. Luminescent and functional molecular organic dyes with balanced hydrophobic/hydrophobic properties that can be effectively absorbed into silk glands of the silkworm are also described.
• US6362006B1
  申请人：——

  公开号：US6362006B1

  公开（公告）日：2002-03-26