2-(2-acetylaminoethyl)dibenzo<1,4>dioxin

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并二恶英
• 英文名称: 2-(2-acetylaminoethyl)dibenzo<1,4>dioxin
• 化学式: C₁₆H₁₅NO₃
• 分子量: 269.3
• InChiKey: GHNUOIMJHAGRKO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.26
• 重原子数：
  20.0
• 可旋转键数：
  3.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.19
• 拓扑面积：
  47.56
• 氢给体数：
  1.0
• 氢受体数：
  3.0

反应信息

• 作为产物：
  描述：

  多巴胺 在 cyclopentadienylruthenium(II) trisacetonitrile hexafluorophosphate 、 sodium acetate 、 potassium carbonate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 38.5h， 生成 2-(2-acetylaminoethyl)dibenzo<1,4>dioxin
  参考文献：
  名称：

  Towards the synthesis of amino[b,e][1,4]dioxin derivatives via cationic ruthenium complexes

  摘要：

  Double nucleophilic aromatic substitution reactions between N-substituted (eta(6)-1,2-dichlorobenzene)RuCp(+) salts and substituted 1,2-benzenediols have been carried out under mild conditions to prepare N-substituted (eta(6)-dibenzo[b,e][1,4]dioxin)ruthenium(II) complexes. The dibenzodioxin ligands were subsequently liberated by photolysis, with radiation from a sunlamp or from a medium pressure Hg lamp (300 nm).

  DOI：

  10.1016/0022-328x(95)05717-4

文献信息

• Towards the synthesis of amino[b,e][1,4]dioxin derivatives via cationic ruthenium complexes
  作者：Richard C. Cambie、George R. Clark、Sheryl L. Coombe、Sally A. Coulson、Peter S. Rutledge、Paul D. Woodgate

  DOI：10.1016/0022-328x(95)05717-4

  日期：1996.1

  Double nucleophilic aromatic substitution reactions between N-substituted (eta(6)-1,2-dichlorobenzene)RuCp(+) salts and substituted 1,2-benzenediols have been carried out under mild conditions to prepare N-substituted (eta(6)-dibenzo[b,e][1,4]dioxin)ruthenium(II) complexes. The dibenzodioxin ligands were subsequently liberated by photolysis, with radiation from a sunlamp or from a medium pressure Hg lamp (300 nm).