2-imidazolinylethanethiol

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑啉类
• 英文名称: 2-imidazolinylethanethiol
• 英文别名: 2-(4,5-Dihydroimidazol-1-yl)ethanethiol
• 化学式: C₅H₁₀N₂S
• 分子量: 130.214
• InChiKey: QIBVUXOEAVFBHJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  8
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  16.6
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  环硫乙烷 、 2-咪唑啉 以 甲苯 为溶剂， 反应 48.0h， 以62%的产率得到2-imidazolinylethanethiol
  参考文献：
  名称：

  New organogermylated compounds N-substituted by naphthylmethylimidazoline hydrochloride, and imidazoline: synthesis and radioprotective activity

  摘要：

  This work concerns the synthesis and pharmacological study (toxicity, radioprotective activity) of the N-substituted organogermylated compounds by naphthylmethylimidazoline hydrochloride and imidazoline. These new organometallic derivatives have quite low toxicity and sometimes higher radioprotective activity (compared with hydrochlorides of naphthylmethylimidazoline and imidazoline).

  DOI：

  10.1016/0223-5234(93)90111-q

文献信息

• New organogermylated compounds N-substituted by naphthylmethylimidazoline hydrochloride, and imidazoline: synthesis and radioprotective activity
  作者：G Rima、J Satgé、H Sentenac-Roumanou、M Fatome、C Lion、JD Laval

  DOI：10.1016/0223-5234(93)90111-q

  日期：1993.1

  This work concerns the synthesis and pharmacological study (toxicity, radioprotective activity) of the N-substituted organogermylated compounds by naphthylmethylimidazoline hydrochloride and imidazoline. These new organometallic derivatives have quite low toxicity and sometimes higher radioprotective activity (compared with hydrochlorides of naphthylmethylimidazoline and imidazoline).