仲丁氧基三甲基硅烷 | 1825-66-7

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 中文名称: 仲丁氧基三甲基硅烷
• 英文名称: sec-butoxytrimethylsilane
• 英文别名: 2-trimethylsilanyloxy-butane；sec-Butoxy-trimethyl-silan；Trimethyl(1-methylpropoxy)silane；butan-2-yloxy(trimethyl)silane
• CAS: 1825-66-7
• 化学式: C₇H₁₈OSi
• 分子量: 146.305
• InChiKey: NPVKWWQBIVSLRO-UHFFFAOYSA-N

物化性质

• 沸点：
  112.3 °C
• 密度：
  0.772 g/cm3(Temp: 22 °C)
• 保留指数：
  745.3

计算性质

• 辛醇/水分配系数(LogP)：
  2.64
• 重原子数：
  9
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

安全信息

• 海关编码：
  2931900090

反应信息

• 作为反应物：
  描述：

  仲丁氧基三甲基硅烷 在 氯化亚砜 作用下， 生成 2-butyl chlorosulfite
  参考文献：
  名称：

  Currell,B.R. et al., Journal of the Chemical Society, 1960, p. 2776 - 2778

  摘要：

  DOI：
• 作为产物：
  描述：

  仲丁醇 生成 仲丁氧基三甲基硅烷
  参考文献：
  名称：

  KROLEVETS, A. A.;ANTIPOVA, V. V.;POPOV, A. G.;ADAMOV, A. V., ZH. OBSHCH. XIMII, 58,(1988) N 10, S. 2274-2281

  摘要：

  DOI：

文献信息

• Synthesis and characterization of a bifunctional nanomagnetic solid acid catalyst (Fe₃ O₄ @CeO₂ /SO₄ ²⁻ ) and investigation of its efficiency in the protection process of alcohols and phenols via hexamethyldisilazane under solvent-free conditions
  作者：Esmaeel Mohammadiyan、Hossein Ghafuri、Ali Kakanejadifard

  DOI：10.1002/jccs.201800056

  日期：2019.2

  synthesized using the coprecipitation method and functionalized by an ammonium sulfate solution to achieve a heterogeneous solid acid Fe3O4@CeO2/SO42− (FCA) catalyst. The synthesized bifunctional catalyst was used in the protection process of alcohols and phenols using hexamethyldisilazane (HMDS) at ambient temperature under solvent‐free conditions. Due to its excellent magnetic properties, FCA can easily be

  在这项研究中，使用共沉淀法合成了Fe 3 O 4 @CeO 2（FC），并通过硫酸铵溶液对其进行了功能化处理，从而获得了非均相的固体酸Fe 3 O 4 @CeO 2 / SO 4 2-（FCA）催化剂。合成的双功能催化剂在环境温度和无溶剂条件下使用六甲基二硅氮烷（HMDS）用于醇和酚的保护过程。由于其优异的磁性，FCA可以很容易地从反应混合物中分离出来并重复使用几次，而不会显着降低其催化活性。纳米催化剂的优异的收率和选择性，简单的分离，低成本和高可回收性是该方法的突出优点。使用不同技术进行表征，例如傅立叶变换红外光谱（FT-IR），扫描电子显微镜（SEM），能量色散X射线光谱（EDX），X射线衍射（XRD）和振动样品磁强计（ VSM）。
• Preparation of Nano Silica Supported Sodium Hydrogen Sulfate: As an Efficient Catalyst for the Trimethyl, Triethyl and<i>t</i>-Butyldimethyl Silylations of Aliphatic and Aromatic Alcohols in Solution and under Solvent-free Conditions
  作者：Abdolreza Abri、Somayeh Ranjdar

  DOI：10.1002/jccs.201300586

  日期：2014.8

  Nano silica supported sodium hydrogen sulfate has been prepared by mixing NaHSO4 with activated Nano silicagel. We wish to report a new method for the synthesis of trimethyl (TMS), triethyl (TES) and t‐butyldimethyl silyl (TBS) ethers from benzylic, allylic, propargylic alcohols, phenols, naphtholes and some of phenolic drugs in the solution and under solvent‐free conditions.

  通过将NaHSO 4与活化的纳米硅胶混合，制备了纳米二氧化硅负载的硫酸氢钠。我们希望报告一种在溶液中和溶液中由苄基，烯丙基，炔丙醇，酚，萘酚和某些酚类药物合成三甲基（TMS），三乙基（TES）和叔丁基二甲基甲硅烷基（TBS）醚的新方法无溶剂条件。
• Silicon-29 NMR Spectra of Trimethylsilylated Alcohols
  作者：Magdalena Kvíčalová、Jan Čermák、Vratislav Blechta、Jan Schraml

  DOI：10.1135/cccc19970816

  日期：——

  ²⁹Si NMR spectra of trimethylsilyl (TMS) derivatives of 26 simple alcohols were measured under standardized conditions (i.e., in sufficiently diluted deuteriochloroform solutions). Due to association with the solvent the chemical shifts are in almost all cases larger than those reported earlier for different solutions. This observation is in agreement with the proposed mechanism of steric effects as being due to sterically controlled association with the solvent. The use of chloroform as a solvent enhances steric effects but at the same time it can reduce small differences due to polar effects in closely related compounds. In the studied class of compounds the gross dependence of the chemical shift on polar effects is not substantially affected by the change of the solvent.

  对26种简单醇类化合物的三甲基硅基（TMS）衍生物的硅核磁共振（29Si NMR）谱进行了测量，采用标准化条件（即，在充分稀释的氘代氯仿溶液中）。由于与溶剂的结合，化学位移在几乎所有情况下均大于早期报告的不同溶液的化学位移。这一观察结果与所提出的机制一致，即由于与溶剂的立体控制结合而产生的立体效应。氯仿作为溶剂的使用增强了立体效应，但同时也可以减小由于极性效应在密切相关化合物中的小差异。在所研究的化合物类别中，化学位移对极性效应的总体依赖性并未受到溶剂变化的实质影响。
• Method for the separation of acids from chemical reaction mixtures by means of ionic fluids
  申请人：Volland Martin

  公开号：US20050020857A1

  公开（公告）日：2005-01-27

  Process for preparing aminodihalophosphines, diaminohalophosphines, triaminophosphines, phosphorous ester diamides, aminophosphines, diaminophosphines, phosphorous ester amide halides and aminophosphine halides with elimination of an acid in the presence of an auxiliary base, wherein the auxiliary base b) and the acid form a salt which is liquid at temperatures at which the desired product is not significantly decomposed during the process of separating off the liquid salt and c) the salt of the auxiliary base forms two immiscible liquid phases with the desired product or the solution of the desired product in a suitable solvent.

  制备氨基二卤代膦、二胺卤代膦、三胺膦、磷酸酯二酰胺、氨基膦、二氨基膦、磷酸酯酰胺卤和氨基膦卤的过程，其中在辅助碱存在下消除酸，辅助碱b）和酸形成一种在所需产品在过程中分离液态盐时不会明显分解的温度下为液态的盐，并且c）辅助碱的盐与所需产品或所需产品在适当溶剂中的溶液形成两个不相溶的液态相。
• SEPARATION OF ACIDS FROM CHEMICAL REACTION MIXTURES BY MEANS OF IONIC LIQUIDS
  申请人：Volland Martin

  公开号：US20080083606A1

  公开（公告）日：2008-04-10

  Process for preparing aminodihalophosphines, diaminohalophosphines, triaminophosphines, phosphorous ester diamides, aminophosphines, diaminophosphines, phosphorous ester amide halides and aminophosphine halides with elimination of an acid in the presence of an auxiliary base, wherein the auxiliary base b) and the acid form a salt which is liquid at temperatures at which the desired product is not significantly decomposed during the process of separating off the liquid salt and c) the salt of the auxiliary base forms two immiscible liquid phases with the desired product or the solution of the desired product in a suitable solvent.

  制备氨基二卤代膦、双氨基卤代膦、三氨基膦、磷酸酯二酰胺、氨基膦、双氨基膦、磷酸酯酰胺卤和氨基膦卤的过程，其中在辅助碱存在下消除酸，该辅助碱b）和酸形成一种盐，在分离液态盐的过程中，所需产物在不显著分解的温度下，该盐是液态的；c）辅助碱的盐与所需产物或所需产物在适当溶剂中的溶液形成两个不相溶的液态相。