(2-tert-butylcyclohexyloxy)(triethyl)silane

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 英文名称: (2-tert-butylcyclohexyloxy)(triethyl)silane
• 英文别名: [(1S,2S)-2-tert-butylcyclohexyl]oxy-triethylsilane
• 化学式: C₁₆H₃₄OSi
• 分子量: 270.531
• InChiKey: MVTOWUXKRSLFNE-CABCVRRESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.61
• 重原子数：
  18
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  三乙基硅烷 、 2-叔-丁基环己酮 在 copper(l) chloride 、 sodium t-butanolate 、 1,3-bis(cyclohexyl)imidazolium tetrafluoroborate 作用下， 以 甲苯 为溶剂， 反应 5.0h， 生成 (2-tert-butylcyclohexyloxy)(triethyl)silane 、 (2-tert-butylcyclohexyloxy)(triethyl)silane
  参考文献：
  名称：

  A Simple and Efficient Copper-Catalyzed Procedure for the Hydrosilylation of Hindered and Functionalized Ketones

  摘要：

  The catalytic hydrosilylation of highly hindered and functionalized ketones is described. The combination of inexpensive catalyst precursors, CuCl and NHC-HX (NHC = N-heterocyclic carbene), leads to a highly efficient reduction mediator for the preparation of silyl ethers from unfunctionalized and functionalized alkyl, cyclic, bicyclic, aromatic, and heteroaromatic ketones. A series of catalyst precursors have been structurally characterized and a catalyst-structure activity relationship is discussed.

  DOI：

  10.1021/jo050397v

文献信息

• A Simple and Efficient Copper-Catalyzed Procedure for the Hydrosilylation of Hindered and Functionalized Ketones
  作者：Silvia Díez-González、Harneet Kaur、Fabiano Kauer Zinn、Edwin D. Stevens、Steven P. Nolan

  DOI：10.1021/jo050397v

  日期：2005.6.1

  The catalytic hydrosilylation of highly hindered and functionalized ketones is described. The combination of inexpensive catalyst precursors, CuCl and NHC-HX (NHC = N-heterocyclic carbene), leads to a highly efficient reduction mediator for the preparation of silyl ethers from unfunctionalized and functionalized alkyl, cyclic, bicyclic, aromatic, and heteroaromatic ketones. A series of catalyst precursors have been structurally characterized and a catalyst-structure activity relationship is discussed.