N,N,4,4-tetramethyl-6-pyrrolidin-1-yl-1H-1,3,5-triazin-2-amine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 三嗪类
• 英文名称: N,N,4,4-tetramethyl-6-pyrrolidin-1-yl-1H-1,3,5-triazin-2-amine
• 化学式: C₁₁H₂₁N₅
• 分子量: 223.32
• InChiKey: DQGAXUJJQMKPDN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  43.2
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Dihydro-1,3,5-triazine amine derivatives and their therapeutic uses
  申请人：Moinet Gerard

  公开号：US20080108619A1

  公开（公告）日：2008-05-08

  The invention relates to the compounds of general formula (I): in which R1, R2, R3, R4, R5 and R6 are as defined in Claim 1. These compounds can be used in the treatment of pathological conditions associated with the insulin-resistance syndrome.
• COMBINATION OF TRIAZINE DERIVATIVES AND HMG-COA REDUCTASE INHIBITORS
  申请人：Moinet Gérard

  公开号：US20100158999A1

  公开（公告）日：2010-06-24

  The present patent application relates to combinations of a triazine derivative with an HMG-CoA reductase inhibitor.
• COMBINATION OF TRIAZINE DERIVATIVES AND PPARalpha AGONISTS
  申请人：Moinet Gérard

  公开号：US20100159005A1

  公开（公告）日：2010-06-24

  The present patent application relates to combinations of triazine derivatives and of PPARα agonists.
• USE OF TRIAZINE DERIVATIVES FOR THE MANUFACTURE OF A MEDICAMENT HAVING A CICATRISING OR ANGIOGENIC EFFECT
  申请人：Moinet Gérard

  公开号：US20100168115A1

  公开（公告）日：2010-07-01

  The present patent application relates to the use of triazine derivatives as cicatrising or angiogenic agents, wherein the triazine is a molecule of formula (I).
• COMBINATION OF TRIAZINE DERIVATIVES AND INSULIN SENSITISERS
  申请人：Moinet Gérard

  公开号：US20100285117A1

  公开（公告）日：2010-11-11

  The present invention relates to combinations of triazine derivatives and of insulin sensitisers.