N-hydroxy 4-{[4-(4-{6-[2-hydroxyethoxy]pyridin-2-yl}-3-methylphenyl)piperidin-1-yl]sulphonyl}tetrahydro-2H-pyran-4-carboxamide | 312930-77-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: N-hydroxy 4-{[4-(4-{6-[2-hydroxyethoxy]pyridin-2-yl}-3-methylphenyl)piperidin-1-yl]sulphonyl}tetrahydro-2H-pyran-4-carboxamide
• 英文别名: N-Hydroxy-4-[(4-{4-[6-(2-hydroxyethoxy)-2-pyridyl]-3-methylphenyl}-1-piperidinyl)sulfonyl]tetrahydro-2H-pyran-4-carboxamide；N-Hydroxy-4-[(4-{4-[6-(2-hydroxyethoxy)-pyridin-2-yl]-3-methylphenyl}-1-piperidinyl)sulfonyl]tetrahydro-2H-pyran-4-carboxamide；N-hydroxy-4-[4-[4-[6-(2-hydroxyethoxy)pyridin-2-yl]-3-methylphenyl]piperidin-1-yl]sulfonyloxane-4-carboxamide
• CAS: 312930-77-1
• 化学式: C₂₅H₃₃N₃O₇S
• 分子量: 519.619
• InChiKey: CCVVNSQMTSBKQT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  36
• 可旋转键数：
  8
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.52
• 拓扑面积：
  147
• 氢给体数：
  3
• 氢受体数：
  9

文献信息

• Wafer
  申请人：——

  公开号：US20030099693A1

  公开（公告）日：2003-05-29

  The present invention concerns a wafer composition comprising: a polymer substrate; a surfactant; and water; characterised in that the wafer further comprises stable, i.e. stable of size and form, crystalline particles of a pharmaceutically active wound healing agent.

  本发明涉及一种晶片组合物，包括：聚合物基底、表面活性剂和水；其特征在于该晶片还包括稳定（即尺寸和形状稳定）的药物活性伤口愈合剂结晶颗粒。
• METALLOPROTEASE INHIBITORS
  申请人：Pfizer Limited

  公开号：EP1181017B1

  公开（公告）日：2003-04-16
• [EN] WAFER FOR WOUNDS<br/>[FR] PASTILLE DESTINEE A SOIGNER DES PLAIES
  申请人：PFIZER LTD

  公开号：WO2003037395A1

  公开（公告）日：2003-05-08

  The present invention concerns a wafer composition comprising: a polymer substrate; a surfactant; and water; characterised in that the wafer further comprises stable, i.e. stable of size and form, crystalline particles of a pharmaceutically active wound healing agent.