(7Z)-7-hydroxyimino-5,5-dimethyl-4,6-dihydro-1,2-benzodithiol-3-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二硫醇
• 英文名称: (7Z)-7-hydroxyimino-5,5-dimethyl-4,6-dihydro-1,2-benzodithiol-3-one
• 化学式: C₉H₁₁NO₂S₂
• 分子量: 229.3
• InChiKey: METDOVRYTKVGFA-POHAHGRESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  14
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  100
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• Compositions and methods for modulating the immune system
  申请人：Prendergast Patrick T.

  公开号：US20090156546A1

  公开（公告）日：2009-06-18

  The present invention provides methods and compositions for the prophylaxis of blood cell disorders such as neutropenia, thrombocytopenia, lymphocytopenia, and anaemia. The invention provides methods wherein compositions comprising at least one cytokinin compound are administered either therapeutically or prophylactically. The invention further has utility in methods of DNA repair.
• COMPOSITIONS AND METHODS FOR MODULATING THE IMMUNE SYSTEM
  申请人：Prendergast Patrick T.

  公开号：US20120196825A1

  公开（公告）日：2012-08-02

  The present invention provides methods and compositions for the prophylaxis of blood cell disorders such as neutropenia, thrombocytopenia, lymphocytopenia, and anaemia. The invention provides methods wherein compositions comprising at least one cytokinin compound are administered either therapeutically or prophylactically. The invention further has utility in methods of DNA repair.
• Compositions and Methods for Preventing and Treating Mucositis and Weight Loss
  申请人：Cascade Estate Ltd.

  公开号：US20130259930A1

  公开（公告）日：2013-10-03

  Pharmaceutical compositions comprising 5-[2-pyrazinyl]-4-methyl-1,2-3-thione or an analogue, derivative, metabolite, prodrug, solvate or a pharmaceutically acceptable salt thereof; and a pharmaceutical carrier, which promotes association with the outer wall of a subject's digestive tract are described as well as their uses in treating and preventing mucositis and cachexia.
• COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING MUCOSITIS AND WEIGHT LOSS
  申请人：ST IP Holding AG

  公开号：US20150031701A1

  公开（公告）日：2015-01-29

  Pharmaceutical compositions comprising 5-[2-pyrazinyl]-4-methyl-1,2-3-thione or an analogue, derivative, metabolite, prodrug, solvate or a pharmaceutically acceptable salt thereof; and a pharmaceutical carrier, which promotes association with the outer wall of a subject's digestive tract are described as well as their uses in treating and preventing mucositis and cachexia.
• [EN] COMPOSITIONS AND METHODS FOR MODULATING THE IMMUNE SYSTEM<br/>[FR] COMPOSITIONS ET MÉTHODES POUR MODULER LE SYSTÈME IMMUNITAIRE
  申请人：PRENDERGAST PATRICK T

  公开号：WO2007131973A2

  公开（公告）日：2007-11-22

  [EN] The present invention provides methods and compositions for the prophylaxis of blood cell disorders such as neutropenia, thrombocytopenia, lymphocytopenia, and anaemia. The invention provides methods wherein compositions comprising at least one cytokinin compound are administered either therapeutically or prophylactically. The invention further has utility in methods of DNA repair.
  [FR] La présente invention concerne des méthodes et des compositions de prophylaxie de troubles cellulaires sanguins tels que de neutropénie, thrombocytopénie, lymphocytopénie et anémie. L'invention concerne des méthodes selon lesquelles des compositions comprenant au moins un composé cytokinine sont administrées soit thérapeutiquement, soit prophylactiquement. L'invention est en outre utile dans des méthodes de réparation d'ADN.