1-Prop-2-enylpiperidin-2-amine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: 1-Prop-2-enylpiperidin-2-amine
• 化学式: C₈H₁₆N₂
• 分子量: 140.23
• InChiKey: NUQXULBNQMDODR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  29.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Dihydropyridine NPY antagonists: piperidine derivatives
  申请人：BRISTOL-MYERS SQUIBB COMPANY

  公开号：EP0747357A2

  公开（公告）日：1996-12-11

  A series of non-peptidergic antagonists of NPY have been synthesized and are comprised of piperidine and tetrahydropyridine derivatives of 4-phenyl-1,4-dihydropyridines of Formula I. As antagonists of NPY-induced feeding behavior, these compounds are expected to act as effective anorexiant agents in promoting weight loss and treating eating disorders.

  一系列 NPY 非肽能拮抗剂已经合成，它们由式 I 的 4-苯基-1,4-二氢吡啶的哌啶和四氢吡啶衍生物组成。 作为 NPY 诱导的摄食行为的拮抗剂，这些化合物有望成为促进减肥和治疗饮食失调的有效厌食剂。
• Dihydropyridine NPY antagonists
  申请人：BRISTOL-MYERS SQUIBB COMPANY

  公开号：EP0747378A1

  公开（公告）日：1996-12-11

  A series of non-peptidergic antagonists of NPY have been synthesized and are comprised of nitrogen heterocyclic derivatives of 4-phenyl-1,4-dihydropyridines of Formula (I). As antagonists of NPY-induced feeding behavior, these compounds are expected to act as effective anorexiant agents in promoting weight loss and trating eating disorders.

  一系列非肽能性 NPY 拮抗剂已经合成，它们由式（I）的 4-苯基-1,4-二氢吡啶的氮杂环衍生物组成。 作为 NPY 诱导的摄食行为的拮抗剂，这些化合物有望成为促进减肥和治疗饮食失调的有效厌食剂。
• Laundry detergent compositions containing a polymer for fabric appearance improvement
  申请人：The Procter & Gamble Company

  公开号：US20010056058A1

  公开（公告）日：2001-12-27

  Detergent compositions and fabric conditioning compositions which include from about 0.01% to about 5.0%, by weight, of polyelectolyte complexes having a compatible charge-balancing polymeric anion with at least 3 anionic groups and a total net charge of at least 4 negative charges.

  洗涤剂组合物和织物护理剂组合物，其中包括约 0.01%至约 5.0%（按重量计）的聚电解质复合物，该复合物具有相容的电荷平衡聚合物阴离子，其阴离子基团至少有 3 个，总净电荷至少有 4 个负电荷。
• Amidoalkyl-piperidine and amidoalkyl-piperazine derivatives useful for the treatment of nervous system disorders
  申请人：——

  公开号：US20020183316A1

  公开（公告）日：2002-12-05

  Novel amidoalkyl-piperidine and amidoalkyl-piperazine derivatives of the general formula 1 wherein all variables are as described herein, useful in the treatment of disorders, such as depression, dementia, schizophrenia, bipolar disorders, anxiety, emesis, acute or neuropathic pain, itching, migraine and movement disorders.

  通式如下的新型酰胺烷基哌啶和酰胺烷基哌嗪衍生物 1 其中所有变量均如本文所述，可用于治疗抑郁症、痴呆症、精神分裂症、双相情感障碍、焦虑症、呃逆、急性或神经性疼痛、瘙痒、偏头痛和运动障碍等疾病。
• Polyelectrolyte complexes and a method for production thereof
  申请人：——

  公开号：US20030078185A1

  公开（公告）日：2003-04-24

  Polyelectrolyte complexes of cationic and anionic polymers which consist of (a) cationic condensates of (i) at least one amine and (ii) a crosslinking agent from the group consisting of epihalohydrins, bishalohydrins of diols, bishalohydrins of polyalkylene glycols, bishalohydrins of polytetrahydrofurans, alkylene dihalides, alkylene trihalides, bisepoxides, trisepoxides, tetraepoxides and/or mixtures of said compounds, and/or quaternized cationic condensates of (i) and (ii), and (b) anionic compounds containing at least three anionic groups and have a charge ratio between anionic and cationic polymers of from 0.01 to 20, and a process for the preparation of the polylectrolyte complexes by mixing the cationic condensates (a) with anionic compounds (b).

  阳离子和阴离子聚合物的聚电解质复合物，由以下物质组成 (a) (i)至少一种胺和(ii)一种交联剂的阳离子缩合物，交联剂包括表卤代烃、二元醇的双卤代烃、聚亚烷基二醇的双卤代烃聚四氢呋喃的双卤水酐、亚烷基二卤化物、亚烷基三卤化物、双环氧化物、三环氧化物、 四环氧化物和/或上述化合物的混合物，和/或(i)和(ii)的季铵化阳离子缩合物，以及 (b) 至少含有三个阴离子基团的阴离子化合物 以及将阳离子缩合物（a）与阴离子化合物（b）混合制备聚电解质复合物的工艺。