1,4,4-三甲基-2,6-哌啶二酮 | 25115-67-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 中文名称: 1,4,4-三甲基-2,6-哌啶二酮
• 英文名称: N,3,3-trimethylglutarimide
• 英文别名: bemeride；1,4,4-trimethyl-piperidine-2,6-dione；1,4,4-Trimethyl-piperidin-2,6-dion；3,3-Dimethyl-glutarsaeure-methylimid；3,3,N-Trimethyl-glutarsaeureimid；Glutarimide, N,3,3-trimethyl-；1,4,4-trimethylpiperidine-2,6-dione
• CAS: 25115-67-7
• 化学式: C₈H₁₃NO₂
• 分子量: 155.197
• InChiKey: FMGADNVMWHSJDJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  37.4
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 海关编码：
  2925190090

反应信息

• 作为反应物：
  描述：

  1,4,4-三甲基-2,6-哌啶二酮 在 三乙胺 、 三氯氧磷 作用下， 以 乙醇 、 氯仿 为溶剂， 反应 44.0h， 生成 3,5-diformyl-1,4,4-trimethyl-2,6-bis(methylthio)-1,4-dihydropyridine
  参考文献：
  名称：

  Kurfuerst, Antonin; Sebek, Pavel, Collection of Czechoslovak Chemical Communications, 1989, vol. 54, # 6, p. 1705 - 1715

  摘要：

  DOI：
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 生成 1,4,4-三甲基-2,6-哌啶二酮
  参考文献：
  名称：

  Lukes; Hofman, Collection of Czechoslovak Chemical Communications, 1958, vol. 23, p. 1110,1118

  摘要：

  DOI：

文献信息

• NEW PHENYLALANINE DERIVATIVES
  申请人：SUZUKI Nobuyasu

  公开号：US20090048236A1

  公开（公告）日：2009-02-19

  Specific phenylalanine derivatives or pharmaceutically acceptable salts thereof have an antagonistic effect on the α4 integrins and, therefore, are usable as therapeutic agents or preventive agents for diseases in which α4 integrin-depending adhesion process participates in the pathology, such as inflammatory diseases, rheumatoid arthritis, inflammatory bowel diseases, systemic lupus erythematosus, multiple sclerosis, Sjögren's syndrome, asthma, psoriasis, allergy, diabetes, cardiovascular diseases, arterial sclerosis, restenosis, tumor proliferation, tumor metastasis and transplantation rejection.

  特定的苯丙氨酸衍生物或其药学上可接受的盐具有对α4整合素的拮抗作用，因此可用作治疗剂或预防剂，用于α4整合素依赖性黏附过程参与病理的疾病，如炎症性疾病、类风湿性关节炎、炎症性肠病、系统性红斑狼疮、多发性硬化症、干燥综合症、哮喘、银屑病、过敏、糖尿病、心血管疾病、动脉硬化、再狭窄、肿瘤增殖、肿瘤转移和移植排斥。
• DIKETOHYDRAZINE DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT
  申请人：Hatayama Akira

  公开号：US20100087442A1

  公开（公告）日：2010-04-08

  The present invention relates to a diketohydrazine derivative of formula (I) and a pharmaceutically acceptable salt thereof (the symbols in the formula have the same meaning as described in the specification). The compound of formula (I) has an inhibitory activity against cysteine protease, and it is useful for the treatment of inflammatory diseases, immune diseases, ischemic diseases, respiratory diseases, circulatory diseases, blood diseases, neuronal diseases, hepatic or biliary diseases, osseous or articular diseases, metabolic diseases, etc. And the compound has inhibitory activity against elastase and it is also useful for the treatment of COPD (chronic obstacle pulmonary diseases).

  本发明涉及式(I)的二酮肼衍生物及其药学上可接受的盐（式中符号与说明书中描述的含义相同）。式(I)化合物具有对半胱氨酸蛋白酶的抑制活性，可用于治疗炎症性疾病、免疫性疾病、缺血性疾病、呼吸系统疾病、循环系统疾病、血液疾病、神经系统疾病、肝胆系统疾病、骨骼或关节疾病、代谢性疾病等。该化合物具有对弹性蛋白酶的抑制活性，也可用于治疗慢性阻塞性肺部疾病（COPD）。
• WAVELENGTH CONVERSION MATERIAL AS ENCAPSULATE FOR SOLAR MODULE SYSTEMS TO ENHANCE SOLAR HARVESTING EFFICIENCY
  申请人：NITTO DENKO CORPORATION

  公开号：US20130139868A1

  公开（公告）日：2013-06-06

  This invention relates to an encapsulation structure comprising a luminescent wavelength conversion material for at least one solar cell or photovoltaic device which acts to enhance the solar harvesting efficiency of the solar cell device. The luminescent wavelength conversion material comprises at least one chromophore and an optically transparent polymer matrix. Application of the encapsulation structure, as disclosed herein, to solar harvesting devices, including solar cells, solar panels, and photovoltaic devices, improves the solar harvesting efficiency of the device by widening the spectrum of incoming sunlight that can be effectively converted into electricity by the device.

  本发明涉及一种封装结构，包括至少一种用于太阳能电池或光伏器件的发光波长转换材料，该材料有助于提高太阳能电池器件的太阳能收集效率。发光波长转换材料包括至少一种色团和一个光学透明的聚合物基质。将本文所述的封装结构应用于太阳能收集器件，包括太阳能电池、太阳能板和光伏器件，通过扩展能够被器件有效转换为电能的入射阳光的频谱，可以提高器件的太阳能收集效率。
• HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR WAVELENGTH CONVERSION
  申请人：RACHWAL Mila

  公开号：US20150340519A1

  公开（公告）日：2015-11-26

  The invention provides highly fluorescent materials comprising a single (i=0) or a series (i=1, 2, etc.) of heterocyclic systems. The chromophores are particularly useful for absorption and emission of photons in the visible and near infrared wavelength range. The photo-stable highly luminescent chromophores are useful in various applications, including in wavelength conversion films. Wavelength conversion films have the potential to significantly enhance the solar harvesting efficiency of photovoltaic or solar cell devices.

  本发明提供了高度荧光材料，包括单个（i = 0）或一系列（i = 1、2等）杂环系统。这些色团特别适用于吸收和发射可见光和近红外波长范围内的光子。这些光稳定的高亮度色团在各种应用中非常有用，包括在波长转换膜中使用。波长转换膜有潜力显著提高光伏或太阳能电池器件的太阳能收集效率。
• WAVELENGTH CONVERSION FILMS WITH MULTIPLE PHOTOSTABLE ORGANIC CHROMOPHORES
  申请人：GU Tao

  公开号：US20160108310A1

  公开（公告）日：2016-04-21

  Described herein are wavelength conversion films which utilize photostable organic chromophores. In some embodiments, wavelength conversion films and chromophores exhibit improved photostability. In some embodiments, a wavelength conversion film comprising luminescent compounds is useful for improving the solar harvesting efficiency of solar cells, solar panels, or photovoltaic devices. In some embodiments, a wavelength conversion film comprising multiple luminescent compounds is useful for greenhouse roofs. Some embodiments provide an improved solar light wavelength profile for improved plant nutrition and/or growth.

  本文描述了利用光稳定有机色团的波长转换薄膜。在某些实施例中，波长转换薄膜和色团表现出改善的光稳定性。在某些实施例中，包含发光化合物的波长转换薄膜可用于提高太阳能电池、太阳能电池板或光伏设备的太阳能收集效率。在某些实施例中，包含多种发光化合物的波长转换薄膜可用于温室屋顶。某些实施例提供了改善植物营养和/或生长的太阳光波长分布。